Hepatoprotective and antioxidant capacity of Melochia corchorifolia extracts

AbstractObjectiveTo evaluate hepato protective and antioxidant capacity of Melochia corchorifolia (M. corchorifolia) aerial part extracts.MethodsAntioxidant activity was evaluated by using three free radicals (Superoxide, Hydroxyl and DPPH) and hepatoprotective activity was assessed against CCl4 induced liver intoxication in rats.ResultsThe extracts produced concentration dependent percentage protection in decrease of serum enzymes and percentage inhibition on free radicals. Among all extracts methanol extract showed better activity with percentage protection of SGOT (78.98%), SGPT (79.65%), ALP (82.48%) and total bilirubin (80.0%) levels against CCl4 liver intoxication and also methanolic extract showed better activity with IC50 values on superoxide, hydroxyl and DPPH radicals were 127 μ g, 240 μ g and 179 μ g.ConclusionsFrom the results obtained during the study it could be concluded that M. corchorifolia aerial part extracts have antioxidant and hepatoprotective components. Further study is necessary for isolation and characterization of bioactive molecules which are responsible for hepatoprotective and antioxidant activity

Antihepatotoxic effect of Elephantopus scaber L. on carbon tetrachloride-induced hepatotoxicity in rats

Elephantopus scaber was used in folk medicine in several countries to treat different diseases. Liver diseases are major World wise health Problems. The Present aim of the study was evaluate The Antihepatotoxic effects of different fractions of Elephantopus scaber against Carbon tetrachloride (CCl4) induced hepatic damage in Rats. All the fractions were given orally in different doses (125mg/kg, 250mg/kg, 500mg/kg). The Antihepatotoxic effect was assessed by measuring serum parameters like  aspertate transaminase (AST), alanine transaminase (ALT), Alkaline Phospatase (ALP) and total bilurubin.  All the fractions of Elephantopus scaber showed Antihepatotoxic effect.The ethanol fraction was shows significant percentage protection than compared to other fractions. Therefore, our study supports the isolation and use of active constituents from Ethanol fraction of Elephantopus scaber in treating of liver disease

Synthesis, structures and reduction chemistry of monophthalocyanine scandium hydroxides

The preparation and structural characterization of a pair of scanditun(III) phthalocyanine hydroxide complexes were achieved by reaction of PcScCl with alkali metal alkoxides, likely via hydrolysis of soluble PcSc-alkoxide intermediates. A Sc2Li2 (mu(3)-OH)(4) cubane supported by two distorted Pc rings of the form (PcSc)(2)(mu(3)-OH)(4)Li-2 (THF)(DME) was isolated from the reaction of PcScCl with (LiOPr)-Pr-i, while a simpler alkali-metal-free [Pc2Sc2(mu(2)-OH)(2)(THE)] was obtained from addition of (NaOBu)-Bu-i; both structures are reminiscent of bent metallocenes, with dihedral angles between the two Pc rings of 50.8 and 37.7 degrees respectively. A soluble PcScOH material can also be obtained directly via hydrolysis of insoluble PcScCl in approximately 95:5 THF:water. Reduction of the Pc ring of PcScCl using KC8 is reversible and generates Pc3- and Pc4--containing materials that were characterized via UV-vis spectroscopy and, where appropriate EPR and H-1 NMR spectroscopy; analogous reductions of the PcScOH-based species were irreversible. Exposure of the air-sensitive, reduced PcScCl-based species to ambient atmosphere generated PcScOH materials analogous to the direct hydrolysis route

Qualitative and quantitative phytochemical screening and in vitro anti oxidant and anti microbial activities of Elephantopus scaber Linn.

Preliminary phytochemical analysis and quantification of total phenols, In-vitro antioxidant and anti microbial activities of the different fractions (hydro alcoholic, hexane, ethyl acetate and methanol) of Elephantopus scaber were carried out against five selected pathogenic bacteria and three fungal species. The plant fraction possesses steroids, triterpinoids, saponins, flavonoides, carbohydrates, glycosides and oils. For total phenolic content gallic acid was taken as a standard, the ethyl acetate fraction contains rich phenolic content than other fractions and the methanol fraction shows more DPPH, superoxide and hydroxyl radical scavenging activity. In Anti-microbial activity study all fractions showed good inhibition zone against three organisms i.e., Escherichia coli, Staphylococcus aureus Klebsiella pneumonia among the other test organisms along with Candida spp (fungal organism)

Copia literal de la ejecutoria de nobleza del Cuerpo de Artillería ... otorgada por el rey de armas de S. M. don Alfonso XIII, D. Luis Rubio de Ganga Yarzo y Bru ...

Tit tomado de la cub.Copia digital. Valladolid : Junta de Castilla y León. Consejería de Cultura y Turismo, 2009-201

The effect of soil on spatial variation of the herbaceous layer modulated by overstorey in an Eastern European poplar-willow forest

The tree species composition can influence the dynamics of herbaceous species and enhance the spatial heterogeneity of the soil. But there is very little evidence on how both overstorey structure and soil properties affect the spatial variation of the herb layer. The aim of this study is to evaluate the factors of the soil and overstorey structure by which it is possible to explain the fine-scale variation of herbaceous layer communities in an Eastern European poplar-willow forest. The research was conducted in the “Dnipro-Orils’kiy” Nature Reserve (Ukraine). The research polygon (48º30’51”N, 34º49”02”E) was laid in an Eastern European poplar-willow forest in the floodplain of the River Protich, which is a left inflow of the River Dnipro. The site consists of 7 transects. Each transect was made up of 15 test points. The distance between rows in the site was 3 m. At the site, we established a plot of 45×21 m, with 105 subplots of 3×3 m organized in a regular grid. The adjacent subplots were in close proximity. Vascular plant species lists were recorded at each 3×3 m subplot along with visual estimates of species cover using the nine-degree Braun-Blanquet scale. Within the plot, all woody stems ≥ 1 cm in diameter at breast height were measured and mapped. Dixon’s segregation index was calculated for tree species to quantify their relative spatial mixing. Based on geobotanical descriptions, a phytoindicative assessment of environmental factors according to the Didukh scale was made. The redundancy analysis was used for the analysis of variance in the herbaceous layer species composition. The geographic coordinates of sampling locations were used to generate a set of orthogonal eigenvector-based spatial variables. Two measurements of the overstorey spatial structure were applied: the distances from the nearest tree of each species and the distance based on the evaluation of spatial density of point objects, which are separate trees. In both cases, the distance matrix of sampling locations was calculated, which provided the opportunity to generate eigenvector-based spatial variables. A kernel smoothed intensity function was used to compute the density of the trees’ spatial distribution from the point patterns’ data. Gaussian kernel functions with various bandwidths were used. The coordinates of sampling locations in the space obtained after the conversion of the trees’ spatial distribution densities were used to generate a set of orthogonal eigenvector-based spatial variables, each of them representing a pattern of particular scale within the extent of the bandwidth area structured according to distance and reciprocal placement of the trees. An overall test of random labelling reveals the total nonrandom distribution of the tree stems within the site. The unexplained variation consists of 43.8%. The variation explained solely by soil variables is equal to 15.5%, while the variation explained both by spatial and soil variables is 18.0%. The measure of the overstorey spatial structure, which is based on the evaluation of its density enables us to obtain different estimations depending on the bandwidth. The bandwidth affects the explanatory capacity of the tree stand. A considerable part of the plant community variation explained by soil factors was spatially structured. The orthogonal eigenvector-based spatial variables (dbMEMs) approach can be extended to quantifying the effect of forest structures on the herbaceous layer community. The measure of the overstorey spatial structure, which is based on the evaluation of its density, was very useful in explaining herbaceous layer community variation

Characterization of the Millimeter-Wave Polarization of Centaurus A with QUaD

Centaurus (Cen) A represents one of the best candidates for an isolated, compact, highly polarized source that is bright at typical cosmic microwave background (CMB) experiment frequencies. We present measurements of the 4 degree by 2 degree region centered on Cen A with QUaD, a CMB polarimeter whose absolute polarization angle is known to 0.5 degrees. Simulations are performed to assess the effect of misestimation of the instrumental parameters on the final measurement and systematic errors due to the field's background structure and temporal variability from Cen A's nuclear region are determined. The total (Q, U) of the inner lobe region is (1.00 +/- 0.07 (stat.) +/- 0.04 (sys.), -1.72 +/- 0.06 +/- 0.05) Jy at 100 GHz and (0.80 +/- 0.06 +/- 0.06, -1.40 +/- 0.07 +/- 0.08) Jy at 150 GHz, leading to polarization angles and total errors of -30.0 +/- 1.1 degrees and -29.1 +/- 1.7 degrees. These measurements will allow the use of Cen A as a polarized calibration source for future millimeter experiments.Comment: 9 pages, 8 figures, v2 matches version published in Ap