79 research outputs found

    Polycystic Ovary Syndrome

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    Cardio-metabolic risk factors in polycystic ovary syndrome

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    Author's accepted version (postprint).This is an Accepted Manuscript of an article published by Nova Science Publishers in Cardiometabolic Diseases and Risk Factors in July 2020.Available online: https://novapublishers.com/shop/cardiometabolic-diseases-and-risk-factors/acceptedVersio

    Vitamin D and Human Reproduction

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    Vitamin D is one of the steroid hormones. The precursor of vitamin D, 7-dehydrocholesterol, which is an intermediary for cholesterol pathway, is available in the skin. Ultraviolet B (UVB) radiation makes the transformation of 7-dehydrocholesterol to provitamin D3, which automatically isomerizes to cholecalciferol (vitamin D3). Vitamin D3 is secreted into blood circulation and carried by the vitamin D–binding protein (VDBP). Around 80–90% of vitamin D is from sunlight-derived production in the skin. A little amount of vitamin D is also extracted from foods and/or additional supplementation. Vitamin D has been well known for its function in maintaining calcium and phosphorus homeostasis and promoting bone mineralization. Accumulating evidence from animal and human studies suggests that vitamin D also modulates reproductive processes in women and men and is involved in many functions of the reproductive system. Vitamin D receptor (VDR) and vitamin D–metabolizing enzymes are found in reproductive tissues of women and men. This chapter presents an up-to-date review for describing the function of vitamin D in female reproduction throughout reproductive ages from menarche to menopause, during pregnancy and lactation, and some disorders affecting women and also the role of vitamin D applied to male fertility

    Association between Maternal Anaemia and Postpartum Depression in an Urban Sample of Pregnant Women in Iran

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    The aim of this prospective study was to determine the relationship between anaemia during pregnancy and postpartum depression. Two hundred eighty-one non-anaemic mothers with singleton and low-risk pregnancy and no history of antidepressant-use were studied. Demographic and reproductive data at week 20 were obtained. Mothers were followed up and haemoglobin (Hb) was checked at delivery. Iranian version of Edinburgh Postpartum Depression Scale (EPDS) was completed 4-6 weeks after delivery. Mean age of the mothers was 26.6\ub14 years. The prevalence of postpartum depression according to EPDS was 5.5%. Binary logistic regression analysis showed that Hb <11 g/dL at delivery would increase the chance of postpartum depression (OR 4.64; 95% CI 1.33-16.08). The results show that diagnosis and treatment of physiologic factors, especially anaemia, would reduce the risk of postpartum depression

    Maternal hyperandrogenism is associated with a higher risk of type 2 diabetes mellitus and overweight in adolescent and adult female offspring : a long‑term population‑based follow‑up study

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    Author’s accepted manuscript (postprint).This is an Accepted Manuscript of an article published by Springer in Journal of Endocrinological Investigation on 19/01/2022.Available online: https://link.springer.com/article/10.1007/s40618-021-01721-2acceptedVersio
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