82 research outputs found
An Unbiased CO Survey Toward the Northern Region of the Small Magellanic Cloud with the Atacama Compact Array. II. CO Cloud Catalog
The nature of molecular clouds and their statistical behavior in sub-solar
metallicity environments are not fully explored yet. We analyzed an unbiased
CO( = 2-1) survey data at a spatial resolution of 2 pc in the northern
region of the Small Magellanic Cloud (SMC) with the Atacama Compact Array to
characterize the CO cloud properties. A cloud decomposition analysis identified
426 spatially/velocity-independent CO clouds and their substructures. Based on
the cross-matching with known infrared catalogs by Spitzer and Herschel, more
than 90% CO clouds show spatial correlations with point sources. We
investigated the basic properties of the CO clouds and found that the
radius-velocity linewidth (-) relation follows the Milky Way
(MW) like power-low exponent, but the intercept is 1.5 times lower than
that in the MW. The mass functions () of the CO luminosity and virial
mass are characterized by an exponent of 1.7, which is consistent with
previously reported values in the Large Magellanic Cloud and MW.Comment: 18 pages, 9 figures. Accepted for publication in The Astrophysical
Journa
Simultaneous Screening of Multiple Mutations by Invader Assay Improves Molecular Diagnosis of Hereditary Hearing Loss: A Multicenter Study
Although etiological studies have shown genetic disorders to be a common cause of congenital/early-onset sensorineural hearing loss, there have been no detailed multicenter studies based on genetic testing. In the present report, 264 Japanese patients with bilateral sensorineural hearing loss from 33 ENT departments nationwide participated. For these patients, we first applied the Invader assay for screening 47 known mutations of 13 known deafness genes, followed by direct sequencing as necessary. A total of 78 (29.5%) subjects had at least one deafness gene mutation. Mutations were more frequently found in the patients with congenital or early-onset hearing loss, i.e., in those with an awareness age of 0–6 years, mutations were significantly higher (41.8%) than in patients with an older age of awareness (16.0%). Among the 13 genes, mutations in GJB2 and SLC26A4 were mainly found in congenital or early-onset patients, in contrast with mitochondrial mutations (12S rRNA m.1555A>G, tRNA(Leu(UUR)) m.3243A>G), which were predominantly found in older-onset patients. The present method of simultaneous screening of multiple deafness mutations by Invader assay followed by direct sequencing will enable us to detect deafness mutations in an efficient and practical manner for clinical use
Sequential Appearance of Immunoglobulins in the Pigs Experimentally Infected with Toxoplasma gondii
Studies on Japanese Encephalitis of Animals in Hokkaido : I. Epidemiological Observation on Horses.
- …