Anticipation is the key to understanding music and the effects of music on emotion

There is certainly a need for a framework to guide the study of the physiological mechanisms underlying the experience of music and the emotions that music evokes. However, this framework should be organised hierarchically, with musical anticipation as its fundamental mechanism

Oral contraception and eye disease: findings in two large cohort studies

AIM : To investigate the relation between oral contraceptive use and certain eye diseases. \ud \ud METHODS : Abstraction of the relevant data from the two large British cohort studies of the effects of oral contraception, the Royal College of General Practitioners' (RCGP) Oral Contraception Study and the Oxford-Family Planning Association (Oxford-FPA) Contraceptive Study. Both cohort studies commenced in 1968 and were organised on a national basis. Between them they have accumulated over 850 000 person years of observation involving 63 000 women. \ud \ud RESULTS : The conditions considered in the analysis were conjunctivitis, keratitis, iritis, lacrimal disease, strabismus, cataract, glaucoma, retinal detachment, and retinal vascular lesions. With the exception of retinal vascular lesions, there was no consistent evidence of important increases in risk of eye diseases in users of oral contraception. There was about a twofold increase in the risk of retinal vascular lesions in recent pill users in both studies (statistically significant only in the RCGP study). The increase was not limited to any specific type of lesion and may well reflect diagnostic bias. \ud \ud CONCLUSION : Oral contraceptive use does not appear to increase the risk of eye disease, with the possible exception of retinal vascular lesions. \ud \ud Keywords: oral contraception; eye disease; cohort studie

Student practices in use of lecture recordings in two first-year courses: Pointers for teaching and learning

Although there is a large body of research that exists internationally about how students use lecture recordings, it is necessary to consider the South African situation, where a large proportion of students entering higher education are underprepared and for whom English is not their first language. This study investigated student use of lecture recordings in two different first-year courses, one a standard mathematics course and the other a quantitative literacy course using a lecture-workshop mode of delivery. The results from this study confirm much of what has been seen internationally, that is, that students value the availability of lecture recordings and perceive that their learning is improved by having access to them. Lecture recordings are used mainly to make up for missed lectures, but also to review material from lectures and improve notes made in lectures. There is also evidence of increased usage of recordings immediately prior to assessments. This study found no evidence of a relationship between lecture attendance and recording usage. It also revealed that the extent of use of lecture recordings differs in different course contexts, and that students with lower academic English competence make significantly greater use of the recordings. Limitations that became apparent due to reliability of data obtained by different methods (from questionnaires and from the learning management system) are discussed. Finally, recommendations are made for classroom practice that could enhance academically immature students’ use of lecture recordings as a valuable learning resource

Hypothesized mechanisms through which acute exercise influences episodic memory

Emerging research demonstrates that exercise is favorably associated with several cognitive outcomes, including episodic memory function. The majority of the mechanistic work describing the underlying mechanisms of this effect has focused on chronic exercise engagement. Such mechanisms include, e.g., chronic exercise-induced neurogenesis, gliogenesis, angiogenesis, cerebral circulation, and growth factor production. Less research has examined the mechanisms through which acute (vs. chronic) exercise subserves episodic memory function. The purpose of this review is to discuss these potential underlying mechanisms, which include, e.g., acute exercise-induced (via several pathways, such as vagus nerve and muscle spindle stimulation) alterations in neurotransmitters, synaptic tagging/capturing, associativity, and psychological attention

‘This neo- natal ménage à trois’: British media framing of transnational surrogacy

Background: Media framing can influence people’s perceptions of social changes in family building, and has the potential to influence their future actions. Objectives: to analyse the type of framing and construction used in British news print of transnational commercial surrogacy. Methods: UK newspapers were searched using the search engine Lexis-Nexis. One hundred ninety seven articles were analysed. Content analysis was undertaken to identify the use of gain, loss, neutral, alarm and vulnerability frames, as well as type of construction (i.e. ethical, social, legal, financial and medical). Four researchers independently analysed articles using a coding strategy. Results: Differences between serious (mainly legal, financial), middle market (legal) and tabloid (social, financial) newspapers were found. There were three main foci; buying babies - affordable only to those wealthy enough to pay for it; the legal complications of transnational surrogacy - reporting a sense of the legal system lagging behind this practice; and gay families - repeatedly questioning their suitability as parents - demonstrating a prevailing heterosexual stereotype about reproduction and parenting. Conclusions: Stereotyping was prevalent and the welfare of children and medical aspects of transnational surrogacy were minimally addressed, indicating the media selectively influences its readership

Knowing me, knowing you: Spontaneous use of mentalistic language for self and other in autism

Recent studies on mentalizing have shown that autistic individuals who pass explicit mentalizing tasks may still have difficulties with implicit mentalizing tasks. This study explores implicit mentalizing by examining spontaneous speech that is likely to contain mentalistic expressions. The spontaneous production of meta-statements provides a clear measure for implicit mentalizing that is unlikely to be learned through experience. We examined the self- and other-descriptions of highly verbally able autistic and non-autistic adults in terms of their spontaneous use of mentalistic language and meta-representational utterances through quantitative and qualitative analysis. We devised a hierarchical coding system that allowed us to study the types of statements produced in comparable conditions for the self and for a familiar other. The descriptions of autistic participants revealed less mentalistic content relating to psychological traits and meta-statements. References to physical traits were similar between groups. Within each group, participants produced a similar pattern of types of mental utterance across ‘self’ and ‘other’ conditions. This suggests that autistic individuals show a unique pattern of mental-state-representation for both self and other. Meta-statements add a degree of complexity to self- and other-descriptions and to the understanding of mental states; their reduction in autism provides evidence for implicit mentalizing difficulties

A multi-level analysis of risky streets and neighbourhoods for dissident republican violence in belfast

This paper uses graph theoretical measures to analyse the relationship between street network usage, as well as other street-and area-level factors, and dissident Republican violence in Belfast. A multi-level statistical model is used. Specifically, we employ an observation-level random-effects (OLRE) Poisson regression and use variables at the street and area levels. Streetand area-level characteristics simultaneously influence where violent incidents occur. For every 10% change in the betweenness value of a street segment, the segment is expected to experience 1.32 times as many incidents. Police stations (IRR: 22.05), protestant churches (IRR: 6.19) and commercial premises (IRR: 1.44) on each street segment were also all found to significantly increase the expected number of attacks. At the small-area level, for every 10% change in the number of Catholic residents, the number of incidents is expected to be 4.45 times as many. The results indicate that along with other factors, the street network plays a role in shaping terrorist target selection. Streets that are more connected and more likely to be traversed will experience more incidents than those that are not. This has important practical implications for the policing of political violence in Northern Ireland generally and for shaping specific targeted interventions

DNA-coated Functional Oil Droplets

Many industrial soft materials often include oil-in-water (O/W) emulsions at the core of their formulations. By using tuneable interface stabilizing agents, such emulsions can self-assemble into complex structures. DNA has been used for decades as a thermoresponsive highly specific binding agent between hard and, recently, soft colloids. Up until now, emulsion droplets functionalized with DNA had relatively low coating densities and were expensive to scale up. Here a general O/W DNA-coating method using functional non-ionic amphiphilic block copolymers, both diblock and triblock, is presented. The hydrophilic polyethylene glycol ends of the surfactants are functionalized with azides, allowing for efficient, dense and controlled coupling of dibenzocyclooctane functionalized DNA to the polymers through a strain-promoted alkyne-azide click reaction. The protocol is readily scalable due to the triblock's commercial availability. Different production methods (ultrasonication, microfluidics and membrane emulsification) are used with different oils (hexadecane and silicone oil) to produce functional droplets in various size ranges (sub-micron, $\sim 20\,\mathrm{\mu m}$ and $> 50\,\mathrm{\mu m}$), showcasing the generality of the protocol. Thermoreversible sub-micron emulsion gels, hierarchical "raspberry" droplets and controlled droplet release from a flat DNA-coated surface are demonstrated. The emulsion stability and polydispersity is evaluated using dynamic light scattering and optical microscopy. The generality and simplicity of the method opens up new applications in soft matter and biotechnological research and industrial advances.Comment: 7 pages, 2 figures, 1 tabl