10,797 research outputs found
AN E-V ANALYSIS OF PRICING ALTERNATIVES FOR LONG-TERM MARKETING CONTRACTS
Demand and Price Analysis, Marketing,
On the dominance of J(P)=0(+) ground states in even-even nuclei from random two-body interactions
Recent calculations using random two-body interactions showed a preponderance
of J(P)=0(+) ground states, despite the fact that there is no strong pairing
character in the force. We carry out an analysis of a system of identical
particles occupying orbits with j=1/2, 3/2 and 5/2 and discuss some general
features of the spectra derived from random two-body interactions. We show that
for random two-body interactions that are not time-reversal invariant the
dominance of 0(+) states in this case is more pronounced, indicating that
time-reversal invariance cannot be the origin of the 0(+) dominance.Comment: 8 pages, 3 tables and 3 figures. Phys. Rev. C, in pres
Spectral ergodicity and normal modes in ensembles of sparse matrices
We investigate the properties of sparse matrix ensembles with particular
regard for the spectral ergodicity hypothesis, which claims the identity of
ensemble and spectral averages of spectral correlators. An apparent violation
of the spectral ergodicity is observed. This effect is studied with the aid of
the normal modes of the random matrix spectrum, which describe fluctuations of
the eigenvalues around their average positions. This analysis reveals that
spectral ergodicity is not broken, but that different energy scales of the
spectra are examined by the two averaging techniques. Normal modes are shown to
provide a useful complement to traditional spectral analysis with possible
applications to a wide range of physical systems.Comment: 22 pages, 15 figure
Association Between Plasma Antibody Responses and Risk for Cryptococcus-Associated Immune Reconstitution Inflammatory Syndrome
Atomic oxygen studies on polymers
The purpose was to study the effects of atomic oxygen on the erosion of polymer based materials. The development of an atomic oxygen neutral beam facility using a SURFATRON surface wave launcher that can produce beam energies between 2 and 3 eV at flux levels as high as approx. 10 to the 17th power atoms/cm (2)-sec is described. Thin film dielectric materials were studied to determine recession rates and and reaction efficiencies as a function of incident beam energy and fluence. Accelerated testing was also accomplished and the values of reaction efficiency compared to available space flight data. Electron microscope photomicrographs of the samples' surface morphology were compared to flight test specimens
easySTORM: a robust, lower-cost approach to localisation and TIRF microscopy
TIRF and STORM microscopy are super-resolving fluorescence imaging modalities for which current implementations on standard microscopes can present significant complexity and cost. We present a straightforward and low-cost approach to implement STORM and TIRF taking advantage of multimode optical fibres and multimode diode lasers to provide the required excitation light. Combined with open source software and relatively simple protocols to prepare samples for STORM, including the use of Vectashield for non-TIRF imaging, this approach enables TIRF and STORM imaging of cells labelled with appropriate dyes or expressing suitable fluorescent proteins to become widely accessible at low cost
The Popeye Domain Containing Genes and Their Function in Striated Muscle
The Popeye domain containing (POPDC) genes encode a novel class of cAMP effector proteins, which are abundantly expressed in heart and skeletal muscle. Here we will review their role in striated muscle as deduced from work in cell and animal models and the recent analysis of patients carrying a missense mutation in POPDC1. Evidence suggests that POPDC proteins control membrane trafficking of interacting proteins. Furthermore, we will discuss the current catalogue of established protein-protein interactions. In recent years, the number of POPDC-interacting proteins is rising and currently includes ion channels (TREK-1), sarcolemma-associated proteins serving functions in mechanical stability (Dystrophin), compartmentalization (Caveolin 3), scaffolding (ZO-1), trafficking (NDRG4, VAMP2/3) and repair (Dysferlin), or acting as a guanine nucleotide exchange factor for Rho-family GTPases (GEFT). Recent evidence suggests that POPDC proteins might also control the cellular level of the nuclear proto-oncoprotein c-Myc. These data suggests that this family of cAMP-binding proteins probably serves multiple roles in striated muscle
Epidemiological analysis of methicillin-resistant Staphylococcus aureus isolates from adult patients with cystic fibrosis
Using pulsed-field gel electrophoresis, we genotyped 21 methicillin-resistant Staphylococcus aureus isolates from patients attending an adult cystic fibrosis unit. Eleven patients exhibited pulsotypes related to 2 locally endemic strains. Eleven chronically colonized patients were assessed over a period of up to 2 years, and all demonstrated a retention of strain type
Hunters and gatherers: Strategies for curriculum mapping and data collection for assuring learning
Assurance of learning is a predominant feature in both quality enhancement and assurance in higher education. Assurance of learning is a process that articulates explicit program outcomes and standards, and systematically gathers evidence to determine the extent to which performance matches expectations. Benefits accrue to the institution through the systematic assessment of whole of program goals. Data may be used for continuous improvement, program development, and to inform external accreditation and evaluation bodies. Recent developments, including the introduction of the Tertiary Education and Quality Standards Agency (TEQSA) will require universities to review the methods they use to assure learning outcomes.
This project investigates two critical elements of assurance of learning: 1. the mapping of graduate attributes throughout a program; and 2. the collection of assurance data. An audit was conducted with twenty five Business Schools in Australian universities to identify current methods of mapping graduate attributes across degree programs and their impact on the curriculum, followed by a review of the systems used to collect and store data.
Our findings indicate that external drivers like professional body accreditation (for example: Chartered Professional Accountants (CPA); Association to Advance Collegiate Schools of Business (AACSB)) and TEQSA are important motivators for assuring learning, and those who were undertaking AACSB accreditation had more robust assurance of learning systems in place. It was reassuring to see that the majority of institutions (96%) had adopted an embedding approach to assuring learning rather than opting for independent standardised testing.
The main challenges that were evident were the development of sustainable processes not considered a burden to academic staff, and obtainment of academic buy in to the benefits of assuring learning rather than assurance being seen as a tick box exercise. This cultural change is the real challenge in assurance of learning practice
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