The Chandrasekhar limit for quark stars

The Chandrasekhar limit for quark stars is evaluated from simple energy balance relations, as proposed by Landau for white dwarfs or neutron stars. It has been found that the limit for quark stars depends on, in addition to the fundamental constants, the Bag constant.Comment: LateX fil

Magnetoplasmonic design rules for active magneto-optics

Light polarization rotators and non-reciprocal optical isolators are essential building blocks in photonics technology. These macroscopic passive devices are commonly based on magneto-optical Faraday and Kerr polarization rotation. Magnetoplasmonics - the combination of magnetism and plasmonics - is a promising route to bring these devices to the nanoscale. We introduce design rules for highly tunable active magnetoplasmonic elements in which we can tailor the amplitude and sign of the Kerr response over a broad spectral range

Atmospheric neutrino flux from 3-dimensional simulation

The atmospheric muon and neutrino flux have been simulated using the same approach which successfully accounted for the recent secondary proton, electron and positron flux measurements in orbit by the AMS experiment. For the muon flux, a good agreement is obtained with the CAPRICE and HEAT data for altitudes ranging from sea level up to about 38 km. The general features of the calculated atmospheric neutrino flux are reported and discussed. The flux obtained at the Super-Kamiokande experiment location are reported and compared with other calculations. For low neutrino energies the flux obtained is significantly smaller than that used in the data analysis of underground experiment. The simulation results for the SOUDAN experiment site are also reported.Comment: 33 pages, 27 figures, 12 tables, final version for Phys. Rev.

ProteinSeq: High-Performance Proteomic Analyses by Proximity Ligation and Next Generation Sequencing

Despite intense interest, methods that provide enhanced sensitivity and specificity in parallel measurements of candidate protein biomarkers in numerous samples have been lacking. We present herein a multiplex proximity ligation assay with readout via realtime PCR or DNA sequencing (ProteinSeq). We demonstrate improved sensitivity over conventional sandwich assays for simultaneous analysis of sets of 35 proteins in 5 µl of blood plasma. Importantly, we observe a minimal tendency to increased background with multiplexing, compared to a sandwich assay, suggesting that higher levels of multiplexing are possible. We used ProteinSeq to analyze proteins in plasma samples from cardiovascular disease (CVD) patient cohorts and matched controls. Three proteins, namely P-selectin, Cystatin-B and Kallikrein-6, were identified as putative diagnostic biomarkers for CVD. The latter two have not been previously reported in the literature and their potential roles must be validated in larger patient cohorts. We conclude that ProteinSeq is promising for screening large numbers of proteins and samples while the technology can provide a much-needed platform for validation of diagnostic markers in biobank samples and in clinical use

Quark-diquark Systematics of Baryons: Spectral Integral Equations for Systems Composed by Light Quarks

For baryons composed by the light quarks ($q=u,d$) we write spectral integral equation using the notion of two diquarks: (i) axial--vector state, $D^{1}_{1}$, with the spin $S_D=1$ and isospin $I_D=1$ and (ii) scalar one, $D^{0}_{0}$, with the spin $S_D=0$ and isospin $I_D=0$. We present spectral integral equations for the $qD^{0}_{0}$ and $qD^{1}_{1}$ states taking into account quark--diquark confinement interaction.Comment: 13 pages, 2 figure

Threshold effect of foreign direct investment on environmental degradation

The aim of this paper is to investigate the threshold effect of foreign direct investment (FDI) on environmental degradation. In empirical analysis, FDI and environmental degradation are jointly determined under the given threshold variable and other exogenous variables. Using carbon dioxide (CO2) emissions per capita as a proxy for environmental degradation, the results show that increasing FDI worsens CO2 emissions after a threshold level of corruption has been reached. Our results demonstrate that increasing FDI will increase CO2 emissions when the degree of corruptibility is relatively high. The study suggests that further FDI and improved environmental quality are competing rather than compatible objectives in high-corruption countries and are compatible rather than competing objectives in low-corruption countries. Higher trade liberalization in low-corruption countries could contribute to negative environmental consequences because of the increased output or economic activity which results from increased trade. The robustness estimation confirms the evidence that pollution and economic development increase together up to a certain income level, after which the trend reverses.info:eu-repo/semantics/publishedVersio

Gene expression profiling in primary breast cancer distinguishes patients developing local recurrence after breast-conservation surgery, with or without postoperative radiotherapy

Introduction Some patients with breast cancer develop local recurrence after breast-conservation surgery despite postoperative radiotherapy, whereas others remain free of local recurrence even in the absence of radiotherapy. As clinical parameters are insufficient for identifying these two groups of patients, we investigated whether gene expression profiling would add further information. Methods We performed gene expression analysis (oligonucleotide arrays, 26,824 reporters) on 143 patients with lymph node-negative disease and tumor-free margins. A support vector machine was employed to build classifiers using leave-one-out cross-validation. Results Within the estrogen receptor-positive (ER+) subgroup, the gene expression profile clearly distinguished patients with local recurrence after radiotherapy (n = 20) from those without local recurrence (n = 80 with or without radiotherapy). The receiver operating characteristic (ROC) area was 0.91, and 5,237 of 26,824 reporters had a P value of less than 0.001 (false discovery rate = 0.005). This gene expression profile provides substantially added value to conventional clinical markers (for example, age, histological grade, and tumor size) in predicting local recurrence despite radiotherapy. Within the ER- subgroup, a weaker, but still significant, signal was found (ROC area = 0.74). The ROC area for distinguishing patients who develop local recurrence from those who remain local recurrence-free in the absence of radiotherapy was 0.66 (combined ER+/ER-). Conclusion A highly distinct gene expression profile for patients developing local recurrence after breast-conservation surgery despite radiotherapy has been identified. If verified in further studies, this profile might be a most important tool in the decision making for surgery and adjuvant therapy

Electromagnetic form factors of the nucleon in a covariant diquark model

We present a simple covariant constituent diquark-quark model for the nucleon. The nucleon is assumed to be composed of a scalar diquark and a quark which interact via a quark exchange. Starting from the Bethe-Salpeter equation, the instantaneous approximation leads to a diquark-quark Salpeter equation. In the Mandelstam formalism, the electromagnetic form factors of the nucleon are calculated for momentum transfers up to q^2 = - 3 \; (\mbox{GeV/c})^2. A remarkable description of the experimental data is obtained. Especially, the model gives nearly the right values for the proton and (negative) neutron charge radii, and a qualitative description of the magnetic form factors.Comment: 17 pages, revtex, 8 figures in additional fil

A study of backward going pp and π−\pi^{-} in νμCC\nu_{\mu}CC interactions with the NOMAD detector

Backward proton and $\pi^-$ production has been studied in $\nu_{\mu}CC$ interactions with carbon nuclei. Detailed analyses of the momentum distributions, of the production rates, and of the general features of events with a backward going particle, have been carried out in order to understand the mechanism producing these particles. The backward proton data have been compared with the predictions of the reinteraction and the short range correlation models.Comment: 29 pages, 14 figures, submitted to Nucl. Phys.