Effects of Local Specialization of Investment Subsides in Italy

In Italy we currently have a lot of national and regional instruments for financial aids to enterprises. Most of them are not specialized, as syntethetized in the following points: 1. they are refferred to the whole Italian territory; 2. they have generic objects (increase of GNP, reduction of growth differences among regions, employment); 3. they are applied to all the sectors of production; 4. they have common methods of application (automatic, discretional,negotiated). This means that we establish general purposes without further specialization even if we fall into particular purposes.In addition to this types of subsides, there are anymore that are specialized both at territorial and at sectorial level. Among these, the most important are distributed by the Territorial Pacts that are one of the instruments of concerted planning. In this paper we firstly define the specialization of some forms of subsidies; then we analize the performance of two samples of enterprises, that are located in the Apulia Region (NUTS III), the first of which has been benefiting from the state support provided by law n.488/92 (Financial support of the productive activities in depressed zones), and the second one that has been benefiting from the support provided by Territorial Pacts. The enterprises performance have been assessed through quantitative index measured by three main relations: 1. Sales / Assets, that is an indicator measuring the firms efficiency. So it indicates if the total value of sales they?ve carried out, can account for the effectuated investments. 2. Profit / Sales, that estimate the enterprise ability to obtain profits, aging in the market, and let us having indications about prospects of success. 3. Profit / Assets, that assess, in a better way, the capacity in terms of global income of the enterprise. Comparing the average of the three indicators considered, related to supported enterprises, with the same indexes of Mediobanca sample about not-supported enterprises, we obtain interesting results. They have proved that: A. the enterprises having supports are, generally, less efficient than those having no support; B. the firms subsided by Territorial Pacts are more efficient than the other ones subsided by law n.488/92. From the investigation it emerges that the subsides territorially oriented are more efficient than the general support, referred to the same area. So, if we privilege efficiency results, putting the effectiveness ones in a secondary position, we probably should prefer an automatic but specialized aid system, at least from the territorial, dimensional and productive point of view according to preference scales. But, if we want to obtain effectiveness standards too, it is necessary to specialize the interventions and determine specific goals and result indicators.

Could the aeronautics-aerospace industry renovate the "poles of growth" model as a path of development?

Could the aeronautics-aerospace industry renovate the "poles of growth" model as a path of local development? The paper aims to introduce a theoretical approach in order to answer the question if nowaday new models of local development at regional level exist and if it is possible to recognize the coexistence of different model in the same time depending by particular characteristics and socio-economic background of an area. The main idea of the paper turns around the possibility to review the model of poles of growth described by Perroux at first time. This idea is supported by the case-study of the aeronautics-aerospace industry that presents a meaningful polarization at the regional level in many European regions and can represent an important path for local development. The sector presents a pyramidal structure having few big companies at top operating as global players as well as a lot of companies at the basis. These form meaningful linkages with local SMES in terms of technical collaboration and knowledge transfer. In this way aeronautics-aerospace industry involves institutional organizations at different levels, researchers, different sized firms and a lot of selected stakeholders. Then aeronautics-aerospace activities represent the starting of a significantly trial to regional development in terms of economic stimulus and fertilization towards innovation diffusion as well. That is way the sector can be defined as a knowledge-science-based one in according to the traditional Pavitt's taxonomy. This aspect is particularly important in the present economic phase because economic theories concord about the idea that knowledge diffusion and news innovation technologies represent the winning tools in the framework of global competition. The model of poles of growth is reviewed in this new perspective with a particular attention to the innovation input-output linkages among companies as well as these and research infrastructure formed by as universities and research institutions, human capital and firms incubators that represent the competitive endogenous factors of an area

Effects of Local Specialization of Investment Subsides in Italy

In Italy we currently have a lot of national and regional instruments for financial aids to enterprises. Most of them are not specialized, as syntethetized in the following points: 1. they are refferred to the whole Italian territory; 2. they have generic objects (increase of GNP, reduction of growth differences among regions, employment); 3. they are applied to all the sectors of production; 4. they have common methods of application (automatic, discretional,negotiated). This means that we establish general purposes without further specialization even if we fall into particular purposes.In addition to this types of subsides, there are anymore that are specialized both at territorial and at sectorial level. Among these, the most important are distributed by the Territorial Pacts that are one of the instruments of concerted planning. In this paper we firstly define the specialization of some forms of subsidies; then we analize the performance of two samples of enterprises, that are located in the Apulia Region (NUTS III), the first of which has been benefiting from the state support provided by law n.488/92 (Financial support of the productive activities in depressed zones), and the second one that has been benefiting from the support provided by Territorial Pacts. The enterprises performance have been assessed through quantitative index measured by three main relations: 1. Sales / Assets, that is an indicator measuring the firms efficiency. So it indicates if the total value of sales they?ve carried out, can account for the effectuated investments. 2. Profit / Sales, that estimate the enterprise ability to obtain profits, aging in the market, and let us having indications about prospects of success. 3. Profit / Assets, that assess, in a better way, the capacity in terms of global income of the enterprise. Comparing the average of the three indicators considered, related to supported enterprises, with the same indexes of Mediobanca sample about not-supported enterprises, we obtain interesting results. They have proved that: A. the enterprises having supports are, generally, less efficient than those having no support; B. the firms subsided by Territorial Pacts are more efficient than the other ones subsided by law n.488/92. From the investigation it emerges that the subsides territorially oriented are more efficient than the general support, referred to the same area. So, if we privilege efficiency results, putting the effectiveness ones in a secondary position, we probably should prefer an automatic but specialized aid system, at least from the territorial, dimensional and productive point of view according to preference scales. But, if we want to obtain effectiveness standards too, it is necessary to specialize the interventions and determine specific goals and result indicators

Higher education and research programme on sustainable development in the Mediterranean region (PESME)

Peer Reviewe

University-Industry Collaboration in the European Regional Context: the Cases of Galicia and Apulia Region

Universities are one of the key actors within national and regional innovation systems. The nature of university-industry collaboration has changed during the last decades and it varies across countries and regions. Different factors determine the interaction among both organizations, from those related to the industrial structure of the territory to others related to institutional and legal frameworks. In this paper we aim at adding to the understanding of this process based on the comparison between two European regions, Apulia in Italy and Galicia in Spain. Our results show that a progressive transition from a separated to a more integrated approach has occurred at the relational framework affecting universities and industry in both regions. Public policies, particularly from the regional level, have been relevant for promoting university-industry collaboration in Galicia and Apulia. Nevertheless, there still remain cultural and institutional barriers, both from the academy and business sphere, which impede a closer and more fruitful interaction. Besides, the poor innovative culture of traditional industries which dominate in both regions, might affect university-industry interaction. However, an adjustment of the university offer in terms of research is also needed as we observe that collaboration is too much biased by the university scientific and departmental specialization and too little by local and regional industrial specialization.Uniwersytety pełnią rolę jednego z kluczowych podmiotów w ramach narodowych i regionalnych systemów innowacji. Charakter współpracy między uniwersytetami i przedsiębiorstwami zmienił się ciągu ostatnich kilkudziesięciu lat, przy czy wykazuje on znaczną różnorodność w poszczególnych krajach i regionach. Interakcję między tymi podmiotami determinuje szereg czynników, począwszy od branżowej struktury terytorium, aż po uwarunkowania instytucjonalne i prawne. Celem artykułu jest poszerzenie rozumienia tego procesu, na podstawie porównania dwóch europejskich regionów (nuts-2) - włoskiej Apulii i hiszpańskiej Galicji. Rezultaty badań wskazują, że w obu regionach nastąpił rozwój od rozproszonego do zintegrowanego podejścia w relacjach między nauką i gospodarką. Istotną rolę w rozwoju współpracy między środowiskiem naukowym i przedsiębiorstwami w Galicji i Apulii odegrała polityka gospodarcza, szczególnie na poziomie regionalnym. Jednocześnie jednak ciągle występują kulturowe i instytucjonalne bariery, zarówno po stronie środowiska akademickiego, jak i biznesowego, które utrudniają właściwe ukierunkowanie i większą efektywność współpracy. Ograniczeniem jest z jednej strony niski poziom kultury innowacyjnej obserwowany w tradycyjnych branżach, które dominują w obu regionach. z drugiej zaś strony, istnieje także potrzeba lepszego dostosowania badań prowadzonych przez uniwersytety, gdyż są one bardziej uzależnione od naukowej i funkcjonalnej specjalizacji uczelni niż lokalnej i regionalnej specjalizacji przemysłu

QUADRUPLE RESCUE THERAPY AFTER FIRST AND SECOND LINE FAILURE FOR HELICOBACTER PYLORI TREATMENT: COMPARISON BETWEEN TWO TETRACYCLINE-BASED REGIMENS

Background & Aims: Antibiotic resistance is the main reason for failure of Helicobacter pylori (H. pylori) treatment. Currently, guidelines recommend a treatment guided by antimicrobial susceptibility testing after two failures. However, microbial culture is not feasible everywhere, and the limited number of effective antibiotics against the bacterium narrows the options; thus a rescue therapy combining antibiotics with a low resistance may be fitting. Methods: Patients who have failed a first-line treatment (either prolonged triple or sequential regimens) and, successively, a levofoxacin-based triple therapy were considered for the study. Subjects underwent urea breath test (UBT), stool antigen test (ST) and endoscopy/histology to confirm the diagnosis. Cytopenia and impaired liver and kidney function were exclusion criteria. Fify-four subjects were randomized 1:1 to two regimens: RMB abeprazole/Rifabutin/Minocycline/Bismuth sub-citrate or MTB Rabeprazole/Tinidazole/ Minocycline/Bismuth sub-citrate both for 10 days. Te results were checked 6 weeks afer the end of therapy with ST/UBT plus endoscopy when indicated. Results: RMB eradicated the bacterium in 21 patients. Two subjects dropped out. Te eradication rate was 77.7% (CI 62.0-93.4%) at intention-to-treat and 84.0% (CI 69.6-98.4%) at per-protocol analysis. MTB was successful in 14 patients (51.9%, CI 33.1-70.7%). No patient withdrew from the treatment for adverse events. Drug-related side effects were reported only in 3 subjects, but in all cases the treatment was carried on. Conclusions: Te association minocycline/rifabutin seems to have a synergic effect and a good therapeutic outcome in patients who have failed at least two previous regimens, although a trial on a large population is needed

HoBi-Like Pestivirus and Its Impact on Cattle Productivity

The clinical features and economic impact of the infection caused by an emerging group of pestiviruses, namely HoBi-like pestivirus, in a cattle herd of southern Italy are reported. In 2011, the virus was first associated with respiratory disease, causing an abortion storm after 1 year and apparently disappearing for the following 3 years after persistently infected calves were slaughtered. However, in 2014, reproductive failures and acute gastroenteritis were observed in the same herd, leading to a marked decrease of productivity. A HoBi-like strain closely related to that responsible for previous outbreaks was detected in several animals. Application of an intensive eradication programme, based on the detection and slaughtering of HoBi-like pestivirus persistently infected animals, resulted in a marked improvement of the productive performances

T Helper Lymphocyte and Mast Cell Immunohistochemical Pattern in Nonceliac Gluten Sensitivity

Background and Aims. Nonceliac gluten sensitivity (NCGS) is a gluten-related emerging condition. Since few data about NCGS histopathology is available, we assessed the markers of lymphocyte and innate immunity activation. Materials and Methods. We retrieved duodenal biopsy samples of patients with NCGS diagnosis according to the Salerno criteria. We selected specimens of positive (seropositive celiac disease/Marsh 1-2 stage) and negative (normal microscopic picture) controls. Immunohistochemistry for CD3 (intraepithelial lymphocytes-IELs), CD4 (T helper lymphocytes), CD8 (T cytotoxic lymphocytes), and CD1a/CD117 (Langerhans/mast cells) was performed. ANOVA plus Bonferroni’s tests were used for statistical analysis. Results. Twenty NCGS, 16 celiac disease, and 16 negative controls were selected. CD3 in NCGS were higher than negative controls and lower than celiac disease (18.5 ± 6.4, 11.9 ± 2.8, and 40.8 ± 8.1 IELs/100 enterocytes; p<0.001). CD4 were lower in NCGS than controls and celiac disease (31.0 ± 22.1, 72.5 ± 29.5, and 103.7 ± 15.7 cells/mm2; p<0.001). CD8 in NCGS were similar to negative controls, but lower than celiac disease (14.0 ± 7.4 and 34.0 ± 7.1 IELs/100 enterocytes, p<0.001). CD117 were higher in NCGS than celiac disease and negative controls (145.8 ± 49.9, 121.3 ± 13.1, and 113.5 ± 23.4 cells/mm2; p=0.009). Conclusions. The combination of CD4 and CD117, as well as IEL characterization, may be useful to support a clinical diagnosis of NCGS

How future surgery will benefit from SARS-COV-2-related measures: a SPIGC survey conveying the perspective of Italian surgeons

COVID-19 negatively affected surgical activity, but the potential benefits resulting from adopted measures remain unclear. The aim of this study was to evaluate the change in surgical activity and potential benefit from COVID-19 measures in perspective of Italian surgeons on behalf of SPIGC. A nationwide online survey on surgical practice before, during, and after COVID-19 pandemic was conducted in March-April 2022 (NCT:05323851). Effects of COVID-19 hospital-related measures on surgical patients' management and personal professional development across surgical specialties were explored. Data on demographics, pre-operative/peri-operative/post-operative management, and professional development were collected. Outcomes were matched with the corresponding volume. Four hundred and seventy-three respondents were included in final analysis across 14 surgical specialties. Since SARS-CoV-2 pandemic, application of telematic consultations (4.1% vs. 21.6%; p &lt; 0.0001) and diagnostic evaluations (16.4% vs. 42.2%; p &lt; 0.0001) increased. Elective surgical activities significantly reduced and surgeons opted more frequently for conservative management with a possible indication for elective (26.3% vs. 35.7%; p &lt; 0.0001) or urgent (20.4% vs. 38.5%; p &lt; 0.0001) surgery. All new COVID-related measures are perceived to be maintained in the future. Surgeons' personal education online increased from 12.6% (pre-COVID) to 86.6% (post-COVID; p &lt; 0.0001). Online educational activities are considered a beneficial effect from COVID pandemic (56.4%). COVID-19 had a great impact on surgical specialties, with significant reduction of operation volume. However, some forced changes turned out to be benefits. Isolation measures pushed the use of telemedicine and telemetric devices for outpatient practice and favored communication for educational purposes and surgeon-patient/family communication. From the Italian surgeons' perspective, COVID-related measures will continue to influence future surgical clinical practice

Virgo gravitational wave detector: Results and perspectives

The Virgo detector reached during the past science run a sensitivity very close to the design one. During the last year the detector has been improved by suspending the main interferometer mirrors with monolithic fibers, with the goal of reducing the thermal noise contribution and testing the new technology. At the same time the design of the next detector improvements are on-going and they will be implemented during the construction of Advanced Virgo