23 research outputs found
Are Entrepreneurial Intentions and Open Innovation complements or substitutes for eliciting activities towards the market commercialization of academic breakthrough technologies?
This paper investigates the interplay between open innovation activities and entrepreneurial intentions in the commercialization process of research results originating from academia. Through qualitative case study research, we identify theoretical mechanisms through the qualitative analysis of five case studies. Our results show that inbound and coupled open innovation activities compensate for lower entrepreneurial intentions among academically oriented scientists. However, establishing partnerships remains challenging, particularly in pre-prototyping phases. Nevertheless, our findings point towards social entrepreneurial intentions as fruitful avenues for stimulating entrepreneurial behaviour in academic scientists
Exploring energy poverty in urban and rural contexts in the Era of climate change: a comparative analysis of European countries and Israel
This article examines the multidimensional problem of energy poverty, focusing on its connections to climate change and its manifestation at rural and urban scales across selected European countries and Israel. The study examined 31 locations in eight countries with diverse geo‐graphical and economic backgrounds: Bosnia and Herzegovina, Greece, North Macedonia, The Netherlands, Portugal, Spain, Slovakia, and Israel. The article aims to understand how winter energy vulnerability in rural and urban locations in these countries could be identified using selected energy poverty indicators and how it evolves under the influence of climate change. A set of sociodemographic, infrastructural, and economic variables, combined with climate analysis, were se‐
lected and assessed fortheir impact on energy poverty. We found that energy poverty in most countries depends significantly on location and regional development. Due to a combination of factors influencing energy poverty, rural households tend to be more vulnerable. Furthermore, climate change consequences will likely leave rural areas more likely to experience energy poverty in the future.info:eu-repo/semantics/publishedVersio
Compendium: On existing and missing links between energy poverty and other scholarly debates
ENGAGER Working Group 4 has just produced an extensive compendium on existing and missing links between energy poverty and other scholarly debates. The compendium is edited Ana Stojilovska (HU), Lidija Zivcic (SI), Ricardo Barbosa (PT), Katrin Grossmann (DE) and Rachel Guyet (FR), with contributions from 10 other authors from across Europe. The compendium is one of the most detailed and extensive reviews of its kind that have been published to date. In the introduction of the compendium, the authors note: We publish this work, undertaken between March 2019 and February 2019, in the midst of a huge worldwide health crisis that will alter life and living circumstances. We are aware that this crisis is likely to impact vulnerable people, among them the energy poor, in severe ways. We only start to understand how important energy is as a basis of living and of participation in society. Staying at home is only possible for those who have a home, and it is bearable only if energy can be used for cooking, heating – and communicating. We see this compendium as a living document that will profit from discussion, revision and updating.info:eu-repo/semantics/publishedVersio
Low Temperature-Dependent Salmonid Alphavirus Glycoprotein Processing and Recombinant Virus-Like Particle Formation
Pancreas disease (PD) and sleeping disease (SD) are important viral scourges in aquaculture of Atlantic salmon and rainbow trout. The etiological agent of PD and SD is salmonid alphavirus (SAV), an unusual member of the Togaviridae (genus Alphavirus). SAV replicates at lower temperatures in fish. Outbreaks of SAV are associated with large economic losses of ∼17 to 50 million $/year. Current control strategies rely on vaccination with inactivated virus formulations that are cumbersome to obtain and have intrinsic safety risks. In this research we were able to obtain non-infectious virus-like particles (VLPs) of SAV via expression of recombinant baculoviruses encoding SAV capsid protein and two major immunodominant viral glycoproteins, E1 and E2 in Spodoptera frugiperda Sf9 insect cells. However, this was only achieved when a temperature shift from 27°C to lower temperatures was applied. At 27°C, precursor E2 (PE2) was misfolded and not processed by host furin into mature E2. Hence, E2 was detected neither on the surface of infected cells nor as VLPs in the culture fluid. However, when temperatures during protein expression were lowered, PE2 was processed into mature E2 in a temperature-dependent manner and VLPs were abundantly produced. So, temperature shift-down during synthesis is a prerequisite for correct SAV glycoprotein processing and recombinant VLP production