Large Graph Analysis in the GMine System

Current applications have produced graphs on the order of hundreds of thousands of nodes and millions of edges. To take advantage of such graphs, one must be able to find patterns, outliers and communities. These tasks are better performed in an interactive environment, where human expertise can guide the process. For large graphs, though, there are some challenges: the excessive processing requirements are prohibitive, and drawing hundred-thousand nodes results in cluttered images hard to comprehend. To cope with these problems, we propose an innovative framework suited for any kind of tree-like graph visual design. GMine integrates (a) a representation for graphs organized as hierarchies of partitions - the concepts of SuperGraph and Graph-Tree; and (b) a graph summarization methodology - CEPS. Our graph representation deals with the problem of tracing the connection aspects of a graph hierarchy with sub linear complexity, allowing one to grasp the neighborhood of a single node or of a group of nodes in a single click. As a proof of concept, the visual environment of GMine is instantiated as a system in which large graphs can be investigated globally and locally

Stathmin 1 in normal and malignant hematopoiesis

Stathmin 1 is a microtubule destabilizer that plays an important role in cell cycle progression, segregation of chromosomes, clonogenicity, cell motility and survival. Stathmin 1 overexpression has been reported in malignant hematopoietic cells and Stathmin 1 inhibition reduces the highly proliferative potential of leukemia cell lines. However, during the differentiation of primary hematopoietic cells, Stathmin 1 expression decreases in parallel to decreases in the proliferative potential of early hematopoietic progenitors. The scope of the present review is to survey the current knowledge and highlight future perspectives for Stathmin 1 in normal and malignant hematopoiesis, with regard to the expression, function and clinical implications of this protein.Stathmin 1 is a microtubule destabilizer that plays an important role in cell cycle progression, segregation of chromosomes, clonogenicity, cell motility and survival. Stathmin 1 overexpression has been reported in malignant hematopoietic cells and Stathm4712660665sem informaçãosem informaçã

BoWFire: Detection of Fire in Still Images by Integrating Pixel Color and Texture Analysis

Emergency events involving fire are potentially harmful, demanding a fast and precise decision making. The use of crowdsourcing image and videos on crisis management systems can aid in these situations by providing more information than verbal/textual descriptions. Due to the usual high volume of data, automatic solutions need to discard non-relevant content without losing relevant information. There are several methods for fire detection on video using color-based models. However, they are not adequate for still image processing, because they can suffer on high false-positive results. These methods also suffer from parameters with little physical meaning, which makes fine tuning a difficult task. In this context, we propose a novel fire detection method for still images that uses classification based on color features combined with texture classification on superpixel regions. Our method uses a reduced number of parameters if compared to previous works, easing the process of fine tuning the method. Results show the effectiveness of our method of reducing false-positives while its precision remains compatible with the state-of-the-art methods.Comment: 8 pages, Proceedings of the 28th SIBGRAPI Conference on Graphics, Patterns and Images, IEEE Pres

Um sistema de compressão de imagens digitais.

Este trabalho apresenta o desenvolvimento de um sistema modular e compacto de compressão de imagens digitais. O sistema foi projetado para suportar imagens médicas e de sensoriamento remoto. O problema da diversidade de formatos de imagens é discutido, e a solução encontrada por esse sistema é apresentado

Quantum state reconstruction using binary data from on/off photodetection

The knowledge of the density matrix of a quantum state plays a fundamental role in several fields ranging from quantum information processing to experiments on foundations of quantum mechanics and quantum optics. Recently, a method has been suggested and implemented in order to obtain the reconstruction of the diagonal elements of the density matrix exploiting the information achievable with realistic on/off detectors, e.g. silicon avalanche photo-diodes, only able to discriminate the presence or the absence of light. The purpose of this paper is to provide an overview of the theoretical and experimental developments of the on/off method, including its extension to the reconstruction of the whole density matrix.Comment: revised version, 11 pages, 6 figures, to appear as a review paper on Adv. Science Let

Direct experimental observation of nonclassicality in ensembles of single photon emitters

In this work we experimentally demonstrate for the first time a recently proposed criterion adressed to detect nonclassical behavior in the fluorescence emission of ensembles of single-photon emitters. In particular, we apply the method to study clusters of NV centres in diamond observed via single-photon-sensitive confocal microscopy. Theoretical considerations on the behavior of the parameter at any arbitrary order in presence of poissonian noise are presented and, finally, the opportunity of detecting manifold coincidences is discussed

Towards joint reconstruction of noise and losses in quantum channels

The calibration of a quantum channel, i.e. the determination of the transmission losses affecting it, is definitely one of the principal objectives in both the quantum communication and quantum metrology frameworks. Another task of the utmost relevance is the identification, e.g. by extracting its photon number distribution, of the noise potentially present in the channel. Here we present a protocol, based on the response of a photon-number-resolving detector at different quantum efficiencies, able to accomplish both of these tasks at once, providing with a single measurement an estimate of the transmission losses as well as the photon statistics of the noise present in the exploited quantum channel. We show and discuss the experimental results obtained in the practical implementation of such protocol, with different kinds and levels of noise.Comment: 6 pages, 4 figure

Total Knee Arthroplasty (TKA): When Do the Risks of TKA Overcome the Benefits? Double Risk of Failure in Patients up to 65 Years Old

Objective: The aim of this study was to document the survival rate in the middle-aged patient group up to 65 years old and to compare it with other age groups of patients undergoing total knee arthroplasty (TKA) for knee osteoarthritis (OA). Design: The Register of Orthopaedic Prosthetic Implants (RIPO) regional registry was used to analyze the results of patients <80 years old affected by primary OA and treated with TKA from 2000 to 2019. The database was investigated according to the age group: younger than 50 years, 50-65 years, or 66-79 years, with the aim to estimate revision surgeries and implant survivorship. Results: A total of 45,488 TKAs for primary OA were included in the analysis (M: 11,388; F: 27,846). The percentage of patients <65 years old increased from 13.5% to 24.8% between 2000 and 2019 (P < 0.0001). The survival analysis showed an overall influence of age on the implant revision rate (P < 0.0001), with an estimated survival rate of 78.7%, 89.4%, and 94.8% at 15 years in the 3 groups, respectively. Compared with the older-aged group, the relative risk of failure was 3.1 (95% confidence interval [CI] = 2.2-4.3; P < 0.001) higher in patients <50 years old and 1.8 (95% CI = 1.6-2.0; P < 0.001) higher in patients 50-65 years old. Conclusions: TKA use in the middle-aged patient population up to 65 years old increased significantly over time. These patients present a double risk of failure with respect to older patients. This is particularly important considering the increasing life expectancy and the emergence of new joint preserving strategies, which could postpone the need for TKA to an older age