The conceptualisation and impact of a post-graduate course in lesson and learning study

This paper tells a story about the design, development and impact of a post-graduate Masters-level module aimed at (1) enabling groups of teachers within schools to develop innovative approaches to teaching and learning on the basis of their own Lesson Studies and (2) creating a school network of excellence for Lesson Study in the area as a context for building a cumulative evidence-base, which focuses on identifying and resolving enduring problems of teaching and learning in schools. The first part of the paper outlines the curriculum for the module and sets the innovative conceptual framework that underpins its design . This framework is innovative because it connects and unifies a number of distinct pedagogical perspectives. It links the methodology of Japanese Lesson Study with Stenhouse’s idea of ‘the teacher as a researcher’ and his ‘process model’ of curriculum development as an alternative to the globally dominant ‘objectives model’. Then in turn, the framework incorporates Marton and Booth’s pedagogical theory of ‘variation’. The paper argues that linking and fusing Lesson Study methodology with this wider context of pedagogical ideas unambiguously renders teacher research as learnin

What about a beta-beam facility for low energy neutrinos?

A novel method to produce neutrino beams has recently been proposed : the beta-beams. This method consists in using the beta-decay of boosted radioactive nuclei to obtain an intense, collimated and pure neutrino beam. Here we propose to exploit the beta-beam concept to produce neutrino beams of low energy. We discuss the applications of such a facility as well as its importance for different domains of physics. We focus, in particular, on neutrino-nucleus interaction studies of interest for various open issues in astrophysics, nuclear and particle physics. We suggest possible sites for a low energy beta-beam facility.Comment: 4 pages, 1 figur

Solar Fusion Cross Sections

We review and analyze the available information for nuclear fusion cross sections that are most important for solar energy generation and solar neutrino production. We provide best values for the low-energy cross-section factors and, wherever possible, estimates of the uncertainties. We also describe the most important experiments and calculations that are required in order to improve our knowledge of solar fusion rates.Comment: LaTeX file, 48 pages (figures not included). To appear in Rev. Mod. Phys., 10/98. All authors now listed. Full postscript version with figures available at http://www.sns.ias.edu/~jnb/Papers/Preprints/nuclearfusion.htm

Mechanical loading of primate fingers on vertical : rock surfaces

Claire Garber Goodman Fund, Department of Anthropology, Dartmouth College; Stamps Scholars Program, Dartmouth Collegehttp://www.sajs.co.zahj2021Mammal Research Institut

Mechanical loading of primate fingers on vertical rock surfaces

Mechanical loading of finger bones (phalanges) can induce angular curvature, which benefits arboreal primates by dissipating forces and economising the recruitment of muscles during climbing. The recent discovery of extremely curved phalanges in a hominin, Homo naledi, is puzzling, for it suggests life in an arboreal milieu, or, alternatively, habitual climbing on vertical rock surfaces. The importance of climbing rock walls is attested by several populations of baboons, one of which uses a 7-m vertical surface to enter and exit Dronkvlei Cave, De Hoop Nature Reserve, South Africa. This rock surface is an attractive model for estimating the probability of extreme mechanical loading on the phalanges of rock-climbing primates. Here we use three-dimensional photogrammetry to show that 82–91% of the climbable surface would generate high forces on the flexor tendon pulley system and severely load the phalanges of baboons and H. naledi. If such proportions are representative of vertical rock surfaces elsewhere, it may be sufficient to induce stress-mitigating curvature in the phalanges of primates

The effectiveness of public health interventions to reduce the health impact of climate change:a systematic review of systematic reviews

Climate change is likely to be one of the most important threats to public health in the coming years. Yet despite the large number of papers considering the health impact of climate change, few have considered what public health interventions may be of most value in reducing the disease burden. We aimed to evaluate the effectiveness of public health interventions to reduce the disease burden of high priority climate sensitive diseases

Efectividad de una intervención motivacional breve para procesos de cambio en jóvenes colombianos consumidores de marihuana

Estudio de casoEste trabajo establece la efectividad de una intervención motivacional breve para procesos de cambio frente al consumo de marihuana en jóvenes colombianos. El programa de prevención selectiva fue implementado mediante la estrategia de taller y los parámetros del modelo transteórico. La intervención motivacional breve afectó los procesos de cambio asociados al consumo de marihuana, siendo efectiva para la muestra seleccionada.1. ANTECEDENTES TEÓRICOS Y EMPÍRICOS 2. JUSTIFICACIÓN Y PLANTEAMIENTO DEL PROBLEMA 3. OBJETIVOS 4. VARIABLES 5. HIPÓTESIS 6. MÉTODO 7. RESULTADOS 8. DISCUSIÓN REFERENCIAS APÉNDICESMaestríaMagister en Psicologí

High-resolution African HLA resource uncovers HLA-DRB1 expression effects underlying vaccine response

How human genetic variation contributes to vaccine effectiveness in infants is unclear, and data are limited on these relationships in populations with African ancestries. We undertook genetic analyses of vaccine antibody responses in infants from Uganda (n = 1391), Burkina Faso (n = 353) and South Africa (n = 755), identifying associations between human leukocyte antigen (HLA) and antibody response for five of eight tested antigens spanning pertussis, diphtheria and hepatitis B vaccines. In addition, through HLA typing 1,702 individuals from 11 populations of African ancestry derived predominantly from the 1000 Genomes Project, we constructed an imputation resource, fine-mapping class II HLA-DR and DQ associations explaining up to 10% of antibody response variance in our infant cohorts. We observed differences in the genetic architecture of pertussis antibody response between the cohorts with African ancestries and an independent cohort with European ancestry, but found no in silico evidence of differences in HLA peptide binding affinity or breadth. Using immune cell expression quantitative trait loci datasets derived from African-ancestry samples from the 1000 Genomes Project, we found evidence of differential HLA-DRB1 expression correlating with inferred protection from pertussis following vaccination. This work suggests that HLA-DRB1 expression may play a role in vaccine response and should be considered alongside peptide selection to improve vaccine design