441 research outputs found
SN1991bg-like supernovae are associated with old stellar populations
SN1991bg-like supernovae are a distinct subclass of thermonuclear supernovae
(SNe Ia). Their spectral and photometric peculiarities indicate their
progenitors and explosion mechanism differ from `normal' SNe Ia. One method of
determining information about supernova progenitors we cannot directly observe
is to observe the stellar population adjacent to the apparent supernova
explosion site to infer the distribution of stellar population ages and
metallicities. We obtain integral field observations and analyse the spectra
extracted from regions of projected radius about the
apparent SN explosion site for 11 91bg-like SNe in both early- and late-type
galaxies. We utilize full-spectrum spectral fitting to determine the ages and
metallicities of the stellar population within the aperture. We find that the
majority of the stellar populations that hosted 91bg-like supernovae have
little recent star formation. The ages of the stellar populations suggest that
that 91bg-like SN progenitors explode after delay times of ,
much longer than the typical delay time of normal SNe Ia, which peaks at .Comment: 12 pages, 3 figures, 3 tables, submitted to Publications of the
Astronomical Society of Australi
Diffuse Galactic antimatter from faint thermonuclear supernovae in old stellar populations
Our Galaxy hosts the annihilation of a few low-energy
positrons every second. Radioactive isotopes capable of supplying such
positrons are synthesised in stars, stellar remnants, and supernovae. For
decades, however, there has been no positive identification of a main stellar
positron source leading to suggestions that many positrons originate from
exotic sources like the Galaxy's central super-massive black hole or dark
matter annihilation. %, but such sources would not explain the
recently-detected positron signal from the extended Galactic disk. Here we show
that a single type of transient source, deriving from stellar populations of
age 3-6 Gyr and yielding ~0.03 of the positron emitter Ti, can
simultaneously explain the strength and morphology of the Galactic positron
annihilation signal and the solar system abundance of the Ti decay
product Ca. This transient is likely the merger of two low-mass white
dwarfs, observed in external galaxies as the sub-luminous, thermonuclear
supernova known as SN1991bg-like.Comment: 28 pages main text with 4 figures in preprint style; 26 pages of
Supplementary Informatio
Phase IIA trial of 1% topical cidofovir for treatment of high-grade perianal squamous intraepithelial neoplasia in HIV-infected men and women (AMC046)
Positron Annihilation in the Galaxy
The 511 keV line from positron annihilation in the Galaxy was the first γ-ray line detected to originate from outside our solar system. Going into the fifth decade since the discovery, the source of positrons is still unconfirmed and remains one of the enduring mysteries in γ-ray astronomy. With a large flux of ∼10−3 γ/cm2/s, after 15 years in operation INTEGRAL/SPI has detected the 511 keV line at >50σ and has performed high-resolution spectral studies which conclude that Galactic positrons predominantly annihilate at low energies in warm phases of the interstellar medium. The results from imaging are less certain, but show a spatial distribution with a strong concentration in the center of the Galaxy. The observed emission from the Galactic disk has low surface brightness and the scale height is poorly constrained, therefore, the shear number of annihilating positrons in our Galaxy is still not well know. Positrons produced in β+-decay of nucleosynthesis products, such as 26Al, can account for some of the annihilation emission in the disk, but the observed spatial distribution, in particular the excess in the Galactic bulge, remains difficult to explain. Additionally, one of the largest uncertainties in these studies is the unknown distance that positrons propagate before annihilation. In this paper, we will summarize the current knowledge base of Galactic positrons, and discuss how next-generation instruments could finally provide the answers.Non peer reviewedFinal Accepted Versio
The study of metaphor as part of Critical Discourse Analysis
This article discusses how the study of metaphoric and more generally, figurative language use contributes to critical discourse analysis (CDA). It shows how cognitive linguists’ recognition of metaphor as a fundamental means of concept- and argument-building can add to CDA's account of meaning constitution in the social context. It then discusses discrepancies between the early model of conceptual metaphor theory and empirical data and argues that discursive-pragmatic factors as well as sociolinguistic variation have to be taken into account in order to make cognitive analyses more empirically and socially relevant. In conclusion, we sketch a modified cognitive approach informed by Relevance Theory within CDA
The ANU WiFeS SuperNovA Program (AWSNAP)
This paper presents the first major data release and survey description for
the ANU WiFeS SuperNovA Program (AWSNAP). AWSNAP is an ongoing supernova
spectroscopy campaign utilising the Wide Field Spectrograph (WiFeS) on the
Australian National University (ANU) 2.3m telescope. The first and primary data
release of this program (AWSNAP-DR1) releases 357 spectra of 175 unique objects
collected over 82 equivalent full nights of observing from July 2012 to August
2015. These spectra have been made publicly available via the WISeREP supernova
spectroscopy repository. We analyse the AWSNAP sample of Type Ia supernova
spectra, including measurements of narrow sodium absorption features afforded
by the high spectral resolution of the WiFeS instrument. In some cases we were
able to use the integral-field nature of the WiFeS instrument to measure the
rotation velocity of the SN host galaxy near the SN location in order to obtain
precision sodium absorption velocities. We also present an extensive time
series of SN 2012dn, including a near-nebular spectrum which both confirms its
"super-Chandrasekhar" status and enables measurement of the sub-solar host
metallicity at the SN site.Comment: Submitted to Publications of the Astronomical Society of Australia
(PASA). Spectra publicly released via WISeREP at
http://wiserep.weizmann.ac.il
AMP Affects Intracellular Ca2+ Signaling, Migration, Cytokine Secretion and T Cell Priming Capacity of Dendritic Cells
The nucleotide adenosine-5′-monophosphate (AMP) can be released by various cell types and has been shown to elicit different cellular responses. In the extracellular space AMP is dephosphorylated to the nucleoside adenosine which can then bind to adenosine receptors. However, it has been shown that AMP can also activate A1 and A2a receptors directly. Here we show that AMP is a potent modulator of mouse and human dendritic cell (DC) function. AMP increased intracellular Ca2+ concentration in a time and dose dependent manner. Furthermore, AMP stimulated actin-polymerization in human DCs and induced migration of immature human and bone marrow derived mouse DCs, both via direct activation of A1 receptors. AMP strongly inhibited secretion of TNF-α and IL-12p70, while it enhanced production of IL-10 both via activation of A2a receptors. Consequently, DCs matured in the presence of AMP and co-cultivated with naive CD4+CD45RA+ T cells inhibited IFN-γ production whereas secretion of IL-5 and IL-13 was up-regulated. An enhancement of Th2-driven immune response could also be observed when OVA-pulsed murine DCs were pretreated with AMP prior to co-culture with OVA-transgenic naïve OTII T cells. An effect due to the enzymatic degradation of AMP to adenosine could be ruled out, as AMP still elicited migration and changes in cytokine secretion in bone-marrow derived DCs generated from CD73-deficient animals and in human DCs pretreated with the ecto-nucleotidase inhibitor 5′-(alpha,beta-methylene) diphosphate (APCP). Finally, the influence of contaminating adenosine could be excluded, as AMP admixed with adenosine desaminase (ADA) was still able to influence DC function. In summary our data show that AMP when present during maturation is a potent regulator of dendritic cell function and point out the role for AMP in the pathogenesis of inflammatory disorders
Timebanking and the co‐production of preventive social care with adults; what can we learn from the challenges of implementing person‐to‐person timebanks in England?
This paper explores the potential contribution of timebanking, an innovative volunteering scheme, to the co-production of preventive social care with adults in England. Interest in volunteering in social care has increased as one proposed solution to the international crisis of a rising demand for services in juxtaposition with decreased resources. Volunteering has been particularly promoted in preventive services that prevent or delay care needs arising. Despite sustained interest in volunteering and co-production in social care, little is known about how theory translates into practice. Reporting implementation data from a Realistic Evaluation of six case studies in England, this paper explores one volunteering scheme, timebanking. The research explores how timebanks were working, what contribution they can make to adult
social care, and whether they are an example of co-production. Data collected included interviews, focus groups or open question responses on surveys from 84 timebank members, and semi-structured interviews with 13 timebank staff. Each timebank was visited at least twice, and all timebank activity was analysed for a period of 12 months. Data were triangulated to improve reliability. The research found that in practice, timebanks were not working as described in theory, there were small
numbers of person-to-person exchanges and some timebanks had abandoned this exchange model. Timebanks faced significant implementation challenges including managing risk and safeguarding and the associated bureaucracy, a paternalistic professional culture and the complexity of the timebank mechanism which required adequate resources. Lessons for timebanks are identified, as well as transferable lessons about co-production and volunteering in social care if such schemes are to be successful in the future
MWA rapid follow-up of gravitational wave transients: prospects for detecting prompt radio counterparts
We present and evaluate the prospects for detecting coherent radio
counterparts to gravitational wave (GW) events using Murchison Widefield Array
(MWA) triggered observations. The MWA rapid-response system, combined with its
buffering mode ( minutes negative latency), enables us to catch any
radio signals produced from seconds prior to hours after a binary neutron star
(BNS) merger. The large field of view of the MWA ( at
120\,MHz) and its location under the high sensitivity sky region of the
LIGO-Virgo-KAGRA (LVK) detector network, forecast a high chance of being
on-target for a GW event. We consider three observing configurations for the
MWA to follow up GW BNS merger events, including a single dipole per tile, the
full array, and four sub-arrays. We then perform a population synthesis of BNS
systems to predict the radio detectable fraction of GW events using these
configurations. We find that the configuration with four sub-arrays is the best
compromise between sky coverage and sensitivity as it is capable of placing
meaningful constraints on the radio emission from 12.6\% of GW BNS detections.
Based on the timescales of four BNS merger coherent radio emission models, we
propose an observing strategy that involves triggering the buffering mode to
target coherent signals emitted prior to, during or shortly following the
merger, which is then followed by continued recording for up to three hours to
target later time post-merger emission. We expect MWA to trigger on
BNS merger events during the LVK O4 observing run, which
could potentially result in two detections of predicted coherent emission.Comment: Accepted for publication in PAS
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