Experimental test on an RC beam equipped with embedded barometric pressure sensors for strains measurement

The current trend in structural health monitoring (SHM) is to install increasingly large numbers of distributed, heterogeneous types of sensors, for a timely and exhaustive detection of any possible damage scenario evolving in the system. These sensors should be low-cost, easy to install, robust and durable. Among others, strain remains one of the most straightforward measurands for monitoring the state of a structural element and for assessing its health condition. However, for application to reinforced concrete structures, currently available strain sensing devices, such as electric strain gauges or fibre optic sensors, do not fully satisfy the aforementioned requirements, generally proving difficult to install, fragile and expensive. In this paper, an innovative monitoring technology, called Smart Steel System (S3), is proposed that measures strains in reinforced concrete members, by incorporating commercial barometric pressure MEMS sensors in appropriate sealed cavities embedded in the reinforcing steel bars. The results of an experimental campaign are reported, in which a reinforced concrete beam, instrumented with both S3 devices and conventional electrical strain gauges, is subjected to increasing loading and unloading cycles until collapse. The tests show the superior robustness of the S3 system during construction and loading as well as its good sensing accuracy, demonstrating its potential for a massive use in SHM applications

Intra-abdominal Adiposity In Preterm Infants: An Explorative Study

Objective: The aim of the present study was to compare the total body fat mass and the intra-abdominal adipose tissue between preterm infants assessed at term corrected age and full-term newborns. Methods: An observational explorative study was conducted. 25 preterm and 10 full term infants were evaluated at 0-1 month of corrected and postnatal age, respectively. The total body fat mass was assessed by means of an air displacement plethysmography system (Pea Pod COSMED, USA) and the intra-abdominal adipose tissue by means of magnetic resonance imaging (software program SliceOMatic, Version 4.3,Tomovision, Canada). Results: Total body fat mass (g) of preterm and term infants was 633 (±183) and 538 (±203) respectively while intra-abdominal fat mass (g) was 14.2 (±4.9) and 19.9 (±11.4). Conclusions: Preterm infants, although exhibiting a total body fat mass higher than full term infants, do not show an increased intra-abdominal adipose tissue

A case report of IgG4-related disease: an insidious path to the diagnosis through kidney, heart and brain

BACKGROUND: IgG4-related disease, described around the years 2000 as a form of autoimmune pancreatitis, is now increasingly accepted as a systemic syndrome. The diagnosis is based on both comprehensive and organ-specific criteria. For the kidney, Mayo clinic classification and the guidelines of the Japanese Nephrology Society are used. Ultimately, together with parameters that characterize every organ or apparatus involved, the key element is the confirmation of growing levels of IgG4 in blood or in tissues. CASE PRESENTATION: We describe a male patient with chronic renal failure associated to hypertension without proteinuria. IgG4-related disease was diagnosed through renal biopsy. After an initial positive response to steroids, he presented tinnitus, and histological assessment showed cerebral and subsequently cardiac damage, both IgG4-related. This case appears unique for the type of histologically documented cardiac and neurological parenchymal involvement, and at the same time, exemplifies the subtle and pernicious course of the disease. Frequently, blurred and non-specific signs prevail. Here, kidney damage was associated with minimal urinary findings, slowly progressive renal dysfunction and other factors that can be equivocated in the differential diagnosis. Neurological involvement was represented by tinnitus alone, while cardiac alterations were completely asymptomatic. CONCLUSIONS: This report is representative of the neurological and cardiac changes described in the literature for IgG4-related disease, which may be correlated or not with the renal form and highlights the need, in some cases, of targeted therapeutic approaches. In addition to glucocorticoids, as in this case, rituximab may be necessary

Challenges in the reuse and upgrade of Pier Luigi Nervi 's structures

The paper presents the overall objectives of a funded research program for the development of a Conservation Plan (CP) for the two halls by Pier Luigi Nervi of the Turin Exhibition Center. The Turin Exhibition Center was conceived immediately after the Second World War to host primarily the annual Automobile Show, in connection with the presence in Turin of the FIAT motor company. The two main pavilions of the Center (Halls B and C) are outstanding examples of a pioneering use, of new advanced methods in reinforced concrete construction, combining innovative prefabrication procedures and the re-invention by Nervi of ferrocement, used to form extremely thin elements. The CP is expected to push and contribute to the preservation of the halls designed and built by Nervi, with special emphasis on structural and seismic vulnerability aspects, also due to concerns raised on the durability of concrete materials and technologies. Re-using these buildings entails the challenge to guarantee new extended service life to concrete structures built many decades ago and faces the need for a seismic assessment of these structures, in compliance to recent Italian standards

Massive Weight Loss Decreases Corticosteroid-Binding Globulin Levels and Increases Free Cortisol in Healthy Obese Patients An adaptive phenomenon?

OBJECTIVE—Obesity, insulin resistance, and weight loss have been associated with changes in hypothalamic-pituitary-adrenal (HPA) axis. So far, no conclusive data relating to this association are available. In this study, we aim to investigate the effects of massive weight loss on cortisol suppressibility, cortisol-binding globulin (CBG), and free cortisol index (FCI) in formerly obese women. RESEARCH DESIGN AND METHODS—Ten glucose-normotolerant, fertile, obese women (BMI >40 kg/m2, aged 38.66 ± 13.35 years) were studied before and 2 years after biliopancreatic diversion (BPD) when stable weight was achieved and were compared with age-matched healthy volunteers. Cortisol suppression was evaluated by a 4-mg intravenous dexamethasone suppression test (DEX-ST). FCI was calculated as the cortisol-to-CBG ratio. Insulin sensitivity was measured by an euglycemic-hyperinsulinemic clamp, and insulin secretion was measured by a C-peptide deconvolution method. RESULTS—No difference was found in cortisol suppression after DEX-ST before or after weight loss. A decrease in ACTH was significantly greater in control subjects than in obese (P = 0.05) and postobese women (P ≤ 0.01) as was the decrease in dehydroepiandrosterone (P ≤ 0.05 and P ≤ 0.01, respectively). CBG decreased from 51.50 ± 12.76 to 34.33 ± 7.24 mg/l (P ≤ 0.01) following BPD. FCI increased from 11.15 ± 2.85 to 18.16 ± 6.82 (P ≤ 0.05). Insulin secretion decreased (52.04 ± 16.71 vs. 30.62 ± 16.32 nmol/m−2; P ≤ 0.05), and insulin sensitivity increased by 163% (P ≤ 0.0001). Serum CBG was related to BMI (r0 = 0.708; P = 0.0001), body weight (r0 = 0.643; P = 0.0001), body fat percent (r0 = 0.462; P = 0.001), C-reactive protein (r0 = 0.619; P = 0.004), and leptin (r0 = 0.579; P = 0.007) and negatively to M value (r0 = −0.603; P = 0.005). CONCLUSIONS—After massive weight loss in morbidly obese subjects, an increase of free cortisol was associated with a simultaneous decrease in CBG levels, which might be an adaptive phenomenon relating to environmental changes. This topic, not addressed before, adds new insight into the complex mechanisms linking HPA activity to obesity

Towards a FOSS Automatic Classification of Defects for Bridges Structural Health Monitoring

Bridges are among the most important structures of any road network. During their service life, they are subject to deterioration which may reduce their safety and functionality. The detection of bridge damage is necessary for proper maintenance activities. To date, assessing the health status of the bridge and all its elements is carried out by identifying a series of data obtained from visual inspections, which allows the mapping of the deterioration situation of the work and its conservation status. There are, however, situations where visual inspection may be difficult or impossible, especially in critical areas of bridges, such as the ceiling and corners. In this contribution, the authors acquire images using a prototype drone with a low-cost camera mounted upward over the body of the drone. The proposed solution was tested on a bridge in the city of Turin (Italy). The captured data was processed via photogrammetric process using the open-source Micmac solution. Subsequently, a procedure was developed with FOSS tools for the segmentation of the orthophoto of the intrados of the bridge and the automatic classification of some defects found on the analyzed structure. The paper describes the adopted approach showing the effectiveness of the proposed methodology