Preliminary Report on Experimental Investigation of Engine Dynamics and Controls for a 48-inch Ram-jet Engine

Engine dynamics and controls data are presented for a ram-jet engine which was operated in a free-jet facility at a Mach number of 2.76 and altitudes from 68,000 to 82,000 feet. The predominant engine dynamic characteristics was dead time, with values ranging from 0.018 to 0.053 sec. The control systems were designed to hold a constant ratio of a diffuser static pressure to an inlet-cone reference static pressure. Response times and percent overshoot to fuel-flow disturbances that would have caused subcritical operation without control are included for a wide range of control settings. For all settings, the control response was fast enough (0.08 to 0.5 sec) to prevent subcritical operation

Altitude free-jet investigation of dynamics of a 28-inch-diameter ram-jet engine

The dynamic response of a 28-inch-diameter ramjet engine was investigated for flight Mach numbers of 2.35 and 2.50 and altitudes of 50,000, 60,000 and 65,000 feet

Experimental Investigation of Diffuser Pressure-ratio Control with Shock-positioning Limit on 28-inch Ram-jet Engine

The performance of a control system designed for variable thrust applications was determined in an altitude free-jet facility at various Mach numbers, altitudes and angles of attack for a wide range of engine operation. The results are presented as transient response characteristics for step disturbances in fuel flow and stability characteristics as a function of control constants and engine operating conditions. The results indicate that the control is capable of successful operation over the range of conditions tested, although variations in engine gains preclude optimum response characteristics at all conditions with fixed control constants

Mental Health Professionals’ Attitudes toward Clients with Antisocial Personality Disorder: An Exploratory Study

This exploratory study examined mental health professionals’ attitudes toward clients with antisocial personality disorder. Specifically, are mental health professionals’ attitudes influenced by (a) personal experiences with criminal victimization, or (b) contact with clients with antisocial personality disorder. A factorial MANOVA and follow-up univariate ANOVAs revealed a statistically significant main effect in relation to participants’ level of clinical contact with clients having antisocial personality disorder. Participants with higher levels of clinical contact were associated with more positive attitudes towards clients. Implications for mental health professionals, supervisors, and counselor educators are discussed, and suggestions for future research are provided

Geographic Differences in Time to Culture Conversion in Liquid Media: Tuberculosis Trials Consortium Study 28. Culture Conversion Is Delayed in Africa

Tuberculosis Trials Consortium Study 28, was a double blind, randomized, placebo-controlled, phase 2 clinical trial examining smear positive pulmonary Mycobacterium tuberculosis. Over the course of intensive phase therapy, patients from African sites had substantially delayed and lower rates of culture conversion to negative in liquid media compared to non-African patients. We explored potential explanations of this finding.In TBTC Study 28, protocol-correct patients (n = 328) provided spot sputum specimens for M. tuberculosis culture in liquid media, at baseline and weeks 2, 4, 6 and 8 of study therapy. We compared sputum culture conversion for African and non-African patients stratified by four baseline measures of disease severity: AFB smear quantification, extent of disease on chest radiograph, cavity size and the number of days to detection of M. tuberculosis in liquid media using the Kaplan-Meier product-limit method. We evaluated specimen processing and culture procedures used at 29 study laboratories serving 27 sites.African TB patients had more extensive disease at enrollment than non-African patients. However, African patients with the least disease by the 4 measures of disease severity had conversion rates on liquid media that were substantially lower than conversion rates in non-African patients with the greatest extent of disease. HIV infection, smoking and diabetes did not explain delayed conversion in Africa. Some inter-site variation in laboratory processing and culture procedures within accepted practice for clinical diagnostic laboratories was found.Compared with patients from non-African sites, African patients being treated for TB had delayed sputum culture conversion and lower sputum conversion rates in liquid media that were not explained by baseline severity of disease, HIV status, age, smoking, diabetes or race. Further investigation is warranted into whether modest variation in laboratory processes substantially influences the efficacy outcomes of phase 2 TB treatment trials or if other factors (e.g., nutrition, host response) are involved.ClinicalTrials.gov NCT00144417

Inferring cost of transport from whole-body kinematics in three sympatric turtle species with different locomotor habits

Chelonians are mechanically unusual vertebrates as an exoskeleton limits their body wall mobility. They generallymove slowly on land and have aquatic or semi-aquatic lifestyles. Somewhat surprisingly, the limitedexperimental work that has been done suggests that their energetic cost of transport (CoT) are relatively low.This study examines the mechanical evidence for CoT in three turtle species that have differing degrees ofterrestrial activity. Our results show that Apolone travels faster than the other two species, and that Chelydra hashigher levels of yaw. All the species show poor mean levels of energy recovery, and, whilst there is considerablevariation, never show the high levels of energy recovery seen in cursorial quadrupeds. The mean mechanical CoTis 2 to 4 times higher than is generally seen in terrestrial animals. We therefore find no mechanical support for alow CoT in these species. This study illustrates the need for research on a wider range of chelonians to discoverwhether there are indeed general trends in mechanical and metabolic energy costs

Identification of a human ortholog of the mouse Dcpp gene locus, encoding a novel member of the CSP-1/Dcpp salivary protein family

Glycolaldehyde is a key molecule in the formation of biologically relevant molecules such as ribose. We report its detection with the Plateau de Bure interferometer towards the Class 0 young stellar object NGC1333 IRAS2A, which is only the second solar-type protostar for which this prebiotic molecule is detected. Local thermodynamic equilibrium analyses of glycolaldehyde, ethylene glycol (the reduced alcohol of glycolaldehyde) and methyl formate (the most abundant isomer of glycolaldehyde) were carried out. The relative abundance of ethylene glycol to glycolaldehyde is found to be ~5 -higher than in the Class 0 source IRAS 16293-2422 (~1), but comparable to the lower limits derived in comets ($\geq$3-6). The different ethylene glycol-to-glycolaldehyde ratios in the two protostars could be related to different CH3OH:CO compositions of the icy grain mantles. In particular, a more efficient hydrogenation on the grains in NGC 1333 IRAS2A would favor the formation of both methanol and ethylene glycol. In conclusion, it is possible that, like NGC 1333 IRAS2A, other low-mass protostars show high ethylene glycol-to-glycolaldehyde abundance ratios. The cometary ratios could consequently be inherited from earlier stages of star formation, if the young Sun experienced conditions similar to NGC1333 IRAS2A.Comment: 11 pages, 5 figures, accepted in A&