Parameter estimation bias of dichotomous logistic item response theory models using different variables

The aim of this study was to examine the precision of item parameter estimation in different sample sizes and test lengths under three parameter logistic model (3PL) item response theory (IRT) model, where the trait measured by a test was not normally distributed or had a skewed distribution.In the study, number of categories (1-0), and item response model were identified as fixed conditions, and sample size, test length variables, and the ability distributions were selected as manipulated conditions. This is a simulation study. So data simulation and data analysis were done via packages in the R programming language. Results of the study showed that item parameter estimations performed under normal distribution were much stronger and bias-free compared to non-normal distribution. Moreover, the sample size had some limited positive effect on parameter estimation. However, the test length had no effect parameter estimation. As a result the importance of normality assumptions for IRT models were highlighted and findings were discussed based on relevant literature

Effect of a novel commercial potassium-oxalate containing tooth-desensitizing mouthrinse on the microhardness of resin composite restorative materials with different monomer compositions

The effects of mouthrinses on dental resin composites have been investigated extensively. However, there is little information available regarding the effects of ‘newly developed mouthrinse’ formulations on the microhardness of different monomer based composite systems. Therefore, the aim of this study was to investigate the effect of a novel potassium-oxalate containing desensitizing mouthrinse on the microhardness of different monomer based composite materials. A hundred and twenty specimens (6mm in diameter and 2mm in height) were prepared for composite resin groups (methacrylate based, DX-511 monomer based and silorane monomer based) and for storage solution groups (artificial saliva and potassium oxalate-containing tooth-desensitizing mouthrinse). After allowing post-polimerization the baseline Knoop microhardness measurements for all specimens were recorded. The specimens were stored in 20 mL mouthwash and artificial saliva for 12 hours at 37ºC. The post-immersion microhardness values of all specimens were also recorded. Data were subjected to ANOVA/Scheffe’s test at a significance level of 0.05. The intra group (pre and post immersion values) comparison of the mean microhardness values of the specimens was done using Wilcoxon signed rank test. The microhardness of the silorane based composite was not affected significantly (p>0.05). The hardness values of the DX-511 monomer based composite and the methacrylate based composite exhibited a slight but not significant microhardness change compared to the baseline values (p>0.05). Studies reported that the effect of mouthrinses on microhardness changes of composite resins may be material dependent, and the hardness change susceptibility of a restorative material may be attributed to its resin matrix or filler type. However, dental monomers as well as the oral care products have an ever-evolving technology and future studies should consider newer products. Potassium oxalate containing mouthrinses, especially alcohol-free ones, may be used safely with dental composites with newly developed low-shrink monomer compositions

Electron and Spin Transport in the Presence of Complex Absorbing Potential

We examine the impact of a complex absorbing potential on electron transport, both in the continuum and on a lattice. This requires the use of non-Hermitian Hamiltonians; the required formalism is briefly outlined. The lattice formulation allows us to study the interesting problem of an electron interacting with a stationary spin, and the subsequent time evolution of the electron and spin properties as the electron is absorbed after the initial interaction. Remarkably, the properties of the localized spin are affected 'at-a-distance' by the interaction of the (now entangled) electron with a complex potential.Comment: to be published in Phys. Rev.

Prognostic factors of perioperative FLOT regimen in operable gastric and gastroesophageal junction tumors: real-life data (Turkish Oncology Group)

Background/aim: Perioperative FLOT regimen is a standard of care in locally advanced operable gastric and GEJ adenocarcinoma. We aimed to determine the efficacy, prognostic factors of perioperative FLOT chemotherapy in real-life gastric and GEJ tumors. Materials and methods: The data of patients who were treated with perioperative FLOT chemotherapy were retrospectively analyzed from 34 different oncology centers in Turkey. Baseline clinical and demographic characteristics, pretreatment laboratory values, histological and molecular characteristics were recorded. Results: A total of 441 patients were included in the study. The median of age our study population was 60 years. The majority of patients with radiological staging were cT3-4N(+) (89.9%, n = 338). After median 13.5 months (IQR: 8.5–20.5) follow-up, the median overall survival was NR (95% CI, NR to NR), and median disease free survival was 22.9 (95% CI, 18.6 to 27.3) months. The estimated overall survival at 24 months was 62%. Complete pathological response (pCR) and near pCR was achieved in 23.8% of all patients. Patients with lower NLR or PLR have significantly longer median OS (p = 0.007 and p = 0.033, respectively), and patients with lower NLR have significantly longer median DFS (p = 0.039), but PLR level did not affect DFS (p = 0.062). The OS and DFS of patients with better ECOG performance scores and those who could receive FLOT as adjuvant chemotherapy instead of other regimens were found to be better. NLR was found to be independent prognostic factor for OS in the multivariant analysis. At least one adverse event reported in 57.6% of the patients and grade 3–4 toxicity was seen in 23.6% patients. Conclusion: Real-life perioperative FLOT regimen in operable gastric and GEJ tumors showed similar oncologic outcomes compared to clinical trials. Better performance status, receiving adjuvant chemotherapy as same regimen, low grade and low NLR and PLR improved outcomes in real-life. However, in multivariate analysis, only NLR affected OS. © TÜBİTAK

Final structure & design parameters of TARLA RF system

Doğan, Mehmet Sinan (Dogus Author) -- Conference full title: 5th International Particle Accelerator Conference, IPAC 2014; International Congress Center DresdenDresden; Germany; 15 June 2014 through 20 June 2014Turkish Accelerator and Radiation Laboratory in Ankara (TARLA) is an oscillator mode IR-FEL facility which is under construction since 2011. ELBE licensed superconducting modules housing TESLA RF cavities have been manufacturing for one year and the first module will be delivered in 2015. He Cryogenic System has also started to be manufacturing at similar time with the accelerator structures. It will be delivered in 2014. High Power RF amplifiers are started to tender procedures and delivery time is planning as 2015. The installation of high power transmission lines have to be completed at the same time with the delivery date of HPRF amplifiers to test the cavities and amplifiers. In this study, the final structural design of high power RF transmission lines and design parameters of RF amplifiers for TARLA is discussed

Determination of periodic deformation from InSAR results using the FFT time series analysis method in Gediz Graben

Permanent Scatterers (PS) point velocities obtained by the interferometric synthetic aperture radar (InSAR) method are generally determined using the linear regression model, which ignores periodic and seasonal effects. In this study, software was developed that can detect periodic effects by applying fast Fourier transformation (FFT) time series analysis to InSAR results. Using the FFT time series analysis, the periodic components of the surface movements at the PS points were determined, and then the annual velocity values free from periodic effects were obtained. The study area was chosen as the Gediz Graben, a tectonically active region where aseismic surface deformations have been observed in recent years. As a result, using the developed method, seasonal effects were successfully determined with the InSAR method at the PS points in the study area with a period of 384 days and an average amplitude of 19 mm. In addition, groundwater level changes of a water well in the region were modeled, and 0.93 correlation coefficient values were calculated between seasonal InSAR displacement values and water level changes. Thus, using the developed methodology, the relationship between the tectonic movement in the Gediz Graben in Turkey and the seasonal movements and the change in the groundwater level was determined

Yb2_{2}Pt2_{2}Pb: Magnetic frustration in the Shastry-Sutherland lattice

We have synthesized single crystals of Yb$_{2}$Pt$_{2}$Pb, which crystallize in the layered U$_{2}$Pt$_{2}$Sn-type structure, where planes of Yb ions lie on a triangular network. We report here the first results of magnetization, specific heat, and electrical resistivity experiments. The lattice constants and high temperature magnetic susceptibility indicate that the Yb ions are trivalent, while Schottky peaks in the specific heat show that the ground state is a well isolated doublet. Significant magnetic anisotropy is observed, with the ratio of susceptibilities perpendicular and parallel to the magnetic planes differing by as much as a factor of 30 at the lowest temperatures. Antiferromagnetic order occurs at a N\'eel temperature $T_{\rm N}$=2.07 K, a transition temperature which is more than an order of magnitude smaller than the mean field interactions reflected by the in-plane Weiss temperature. Further evidence for short ranged magnetic fluctuations is found in the magnetic susceptibility and electrical resistivity, which have broad peaks above $T_{\rm N}$, and in the slow development of the magnetic entropy at $T_{\rm N}$. Our experiments indicate that Yb$_{2}$Pt$_{2}$Pb is a quasi-two dimensional and localized moment system, where strong magnetic frustration may arise from the geometry of the underlying Shastry-Sutherland lattice.Comment: 8 pages, 8 figure