Triterpenoids

This review covers the isolation and structure determination of triterpenoids reported during 2012 including squalene derivatives, lanostanes, holostanes, cycloartanes, cucurbitanes, dammaranes, euphanes, tirucallanes, tetranortriterpenoids, quassinoids, lupanes, oleananes, friedelanes, ursanes, hopanes, serratanes, isomalabaricanes and saponins; 348 references are cited

Influence of quantum confinement on the ferromagnetism of (Ga,Mn)As diluted magnetic semiconductor

We investigate the effect of quantum confinement on the ferromagnetism of diluted magnetic semiconductor Ga$_{1-x}$Mn$_x$As using a combination of tight-binding and density functional methods. We observe strong majority-spin Mn $d$-As $p$ hybridization, as well as half metallic behavior, down to sizes as small as 20 \AA in diameter. Below this critical size, the doped holes are self-trapped by the Mn-sites, signalling both valence and electronic transitions. Our results imply that magnetically doped III-V nanoparticles will provide a medium for manipulating the electronic structure of dilute magnetic semiconductors while conserving the ferromagnetic properties and even enhancing it in certain size regime.Comment: 4 pages, 3 figure

Converging shocks in elastic-plastic solids

We present an approximate description of the behavior of an elastic-plastic material processed by a cylindrically or spherically symmetric converging shock, following Whitham's shock dynamics theory. Originally applied with success to various gas dynamics problems, this theory is presently derived for solid media, in both elastic and plastic regimes. The exact solutions of the shock dynamics equations obtained reproduce well the results obtained by high-resolution numerical simulations. The examined constitutive laws share a compressible neo-Hookean structure for the internal energy e = e_(s)(I_1)+e_(h)(ρ,ς), where e_(s) accounts for shear through the first invariant of the Cauchy–Green tensor, and e_(h) represents the hydrostatic contribution as a function of the density ρ and entropy ς. In the strong-shock limit, reached as the shock approaches the axis or origin r=0, we show that compression effects are dominant over shear deformations. For an isothermal constitutive law, i.e., e_(h) = e_(h)(ρ), with a power-law dependence e_(h) ∝ ρ_(α), shock dynamics predicts that for a converging shock located at r=R(t) at time t, the Mach number increases as M ∝ [log(1/R)]^α, independently of the space index s, where s=2 in cylindrical geometry and 3 in spherical geometry. An alternative isothermal constitutive law with p(ρ) of the arctanh type, which enforces a finite density in the strong-shock limit, leads to M ∝ R^(−(s−1)) for strong shocks. A nonisothermal constitutive law, whose hydrostatic part eh is that of an ideal gas, is also tested, recovering the strong-shock limit M∝R^(−(s−1)/n(γ)) originally derived by Whitham for perfect gases, where γ is inherently related to the maximum compression ratio that the material can reach, (γ+1)/(γ−1). From these strong-shock limits, we also estimate analytically the density, radial velocity, pressure, and sound speed immediately behind the shock. While the hydrostatic part of the energy essentially commands the strong-shock behavior, the shear modulus and yield stress modify the compression ratio and velocity of the shock far from the axis or origin. A characterization of the elastic-plastic transition in converging shocks, which involves an elastic precursor and a plastic compression region, is finally exposed

Examining the role of mental health and clinical issues within talent development

Although significant research supports the association between physical activity and mental wellbeing, current literature acknowledges that athletes are no less susceptible to mental illness than the general population. Despite welcomed initiatives aimed at improving mental health within elite sport, these programs often fail to target young athletes; an important concern given that the genesis of many mental illnesses are recognized to occur during this critical period. Given the importance of early intervention and effective treatment, and the potentially devastating consequences of clinical issues going undiagnosed, the implications for talent identification and development become obvious. With this in mind, this study sought to examine the range of mental health issues that may impact upon developing athletes and potential consequences for the development process, specific risk and protective factors associated with talent development, along with an examination of current practices concerning the identification of mental health issues in such environments. Qualitative interviews were conducted with purposively sampled clinicians (n = 8) experienced in working with adolescents and/or young athletes. Inductive content analysis was undertaken, identifying four main themes: key behavioral indicators; associated risk factors; associated protective factors; and issues around identification and diagnosis. Key behavioral indicators included behavioral change, along with behaviors associated with eating disorders, anxiety and depression. Risk factors centered on family background, the performance environment, and issues surrounding adolescence. Protective factors were primarily social in nature. Finally, a lack of awareness and understanding of clinical issues, multiple causes of symptoms, non-disclosure and the need for triangulation of assessment were identified. The need for improved identification and intervention strategies was apparent, with coaches identified as well placed to detect general ‘warning signs’ such as behavioral change. Short of integrating trained clinicians into talent development environments, as part of a triangulation process, ecologically validated assessment tools – coupled with appropriate training and signposting – could offer a practical way of flagging potential issues in developing athletes. The need for the development of such an instrument is therefore apparent. Finally, education around the influential role of family is also recommended in order to promote the protective elements and mitigate risk factors

Polarization Properties of A Multi-Moded Concentrator

We present the design and performance of a non-imaging concentrator for use in broad-band polarimetry at millimeter through submillimeter wavelengths. A rectangular geometry preserves the input polarization state as the concentrator couples f/2 incident optics to a 2 pi sr detector. Measurements of the co-polar and cross-polar beams in both the few-mode and highly over-moded limits agree with a simple model based on mode truncation. The measured co-polar beam pattern is nearly independent of frequency in both linear polarizations. The cross-polar beam pattern is dominated by a uniform term corresponding to polarization efficiency 94%. After correcting for efficiency, the remaining cross-polar response is -18 dB.Comment: 9 pages including 8 figures. Accepted for publication in the Journal of the Optical Society of America

Cryogenic flux-concentrator

Flux concentrator has high primary to secondary coupling efficiency enabling it to produce high magnetic fields. The device provides versatility in pulse duration, magnetic field strengths and power sources

Can my mechanic fix blue cars? A discussion of health clinician\u27s interactions with Aboriginal Australian clients

We expect our professional mechanics to ‘diagnose’ and \u27treat\u27 our cars irrespective of colour, but are we expecting less from our health professionals? There is an increasing focus in the literature on health practitioner decision-making and its influence on the nature and quality of health care. In this article we explore how the basic diagnostic and therapeutic skills that health care practitioners have should be utilised equitably for all clients and propose ways this might be realised. Could the development of Indigenous specific curricula be teaching our medical students to think that Aboriginal patients are different from the norm? We conclude that despite the gains in introducing more comprehensive Aboriginal health curricula there remains considerable work to be done before we can be confident that we are ensuring that health practitioners are no longer contributing to health disparities

An evolutionary approach to the optimisation of autonomous pod distribution for application in an urban transportation service

For autonomous vehicles (AVs), which when deployed in urban areas are called “pods”, to be used as part of a commercially viable low-cost urban transport system, they will need to operate efficiently. Among ways to achieve efficiency, is to minimise time vehicles are not serving users. To reduce the amount of wasted time, this paper presents a novel approach for distribution of AVs within an urban environment. Our approach uses evolutionary computation, in the form of a genetic algorithm (GA), which is applied to a simulation of an intelligent transportation service, operating in the city of Coventry, UK. The goal of the GA is to optimise distribution of pods, to reduce the amount of user waiting time. To test the algorithm, real-world transport data was obtained for Coventry, which in turn was processed to generate user demand patterns. Results from the study showed a 30% increase in the number of successful journeys completed in a 24 hours, compared to a random distribution. The implications of these findings could yield significant benefits for fleet management companies. These include increases in profits per day, a decrease in capital cost, and better energy efficiency. The algorithm could also be adapted to any service offering pick up and drop of points, including package delivery and transportation of goods