Potential isomorphism of elementary substructures of a strictly stable homogeneous model

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Compression-based Modelling of Musical Similarity Perception

Similarity is an important concept in music cognition research since the similarity between (parts of) musical pieces determines perception of stylistic categories and structural relationships between parts of musical works. The purpose of the present research is to develop and test models of musical similarity perception inspired by a transformational approach which conceives of similarity between two perceptual objects in terms of the complexity of the cognitive operations required to transform the representation of the first object into that of the second, a process which has been formulated in informationtheoretic terms. Specifically, computational simulations are developed based on compression distance in which a probabilistic model is trained on one piece of music and then used to predict, or compress, the notes in a second piece. The more predictable the second piece according to the model, the more efficiently it can be encoded and the greater the similarity between the two pieces. The present research extends an existing information-theoretic model of auditory expectation (IDyOM) to compute compression distances varying in symmetry and normalisation using high-level symbolic features representing aspects of pitch and rhythmic structure. Comparing these compression distances with listeners’ similarity ratings between pairs of melodies collected in three experiments demonstrates that the compression-based model provides a good fit to the data and allows the identification of representations, model parameters and compression-based metrics that best account for musical similarity perception. The compression-based model also shows comparable performance to the best-performing algorithms on the MIREX 2005 melodic similarity task

Survey of large protein complexes D. vulgaris reveals great structural diversity

An unbiased survey has been made of the stable, most abundant multi-protein complexes in Desulfovibrio vulgaris Hildenborough (DvH) that are larger than Mr {approx} 400 k. The quaternary structures for 8 of the 16 complexes purified during this work were determined by single-particle reconstruction of negatively stained specimens, a success rate {approx}10 times greater than that of previous 'proteomic' screens. In addition, the subunit compositions and stoichiometries of the remaining complexes were determined by biochemical methods. Our data show that the structures of only two of these large complexes, out of the 13 in this set that have recognizable functions, can be modeled with confidence based on the structures of known homologs. These results indicate that there is significantly greater variability in the way that homologous prokaryotic macromolecular complexes are assembled than has generally been appreciated. As a consequence, we suggest that relying solely on previously determined quaternary structures for homologous proteins may not be sufficient to properly understand their role in another cell of interest

A computational study on outliers in world music

The comparative analysis of world music cultures has been the focus of several ethnomusicological studies in the last century. With the advances of Music Information Retrieval and the increased accessibility of sound archives, large-scale analysis of world music with computational tools is today feasible. We investigate music similarity in a corpus of 8200 recordings of folk and traditional music from 137 countries around the world. In particular, we aim to identify music recordings that are most distinct compared to the rest of our corpus. We refer to these recordings as ‘outliers’. We use signal processing tools to extract music information from audio recordings, data mining to quantify similarity and detect outliers, and spatial statistics to account for geographical correlation. Our findings suggest that Botswana is the country with the most distinct recordings in the corpus and China is the country with the most distinct recordings when considering spatial correlation. Our analysis includes a comparison of musical attributes and styles that contribute to the ‘uniqueness’ of the music of each country

Projection structure of the surface layer of methanoplanus limicola at 10-angstrom resolution obtained by electron cryomicroscopy

The projection structure of the surface protein layer of the archaeon Methanoplanus limicola was analysed by electron microscopy and correlation averaging techniques to a resolution of about 1 nm. For electron microscopy the 2D crystalline protein layer was embedded in aurothioglucose. in order to minimize beam damage, specimen drift, charging and other effects degrading the images, cryomicroscopy at -120 degrees C in combination with spot-scan illumination technique with spot sizes in the range from 200 to 1000 nm was used for recording the images. (C) 1996 Academic Press, Inc. [References: 16