27,107 research outputs found
Nanowires: A route to efficient thermoelectric devices
Miniaturization of electronic devices aims at manufacturing ever smaller
products, from mesoscopic to nanoscopic sizes. This trend is challenging
because the increased levels of dissipated power demands a better understanding
of heat transport in small volumes. A significant amount of the consumed energy
is transformed into heat and dissipated to the environment. Thermoelectric
materials offer the possibility to harness dissipated energy and make devices
less energy-demanding. Heat-to-electricity conversion requires materials with a
strongly suppressed thermal conductivity but still high electronic conduction.
Nanowires can meet nicely these two requirements because enhanced phonon
scattering at the surface and defects reduces the lattice thermal conductivity
while electric conductivity is not deteriorated, leading to an overall
remarkable thermoelectric efficiency. Therefore, nanowires are regarded as a
promising route to achieving valuable thermoelectric materials at the
nanoscale. In this paper, we present an overview of key experimental and
theoretical results concerning the thermoelectric properties of nanowires. The
focus of this review is put on the physical mechanisms by which the efficiency
of nanowires can be improved. Phonon scattering at surfaces and interfaces,
enhancement of the power factor by quantum effects and topological protection
of electron states to prevent the degradation of electrical conductivity in
nanowires are thoroughly discussed
Voltage dip generator for testing wind turbines connected to electrical networks
This paper describes a new voltage dip generator that allows the shape of the time profile of the voltage generated to be configured. The use of this device as a tool to test the fault ride-through capability of wind turbines connected to the electricity grid can provide some remarkable benefits: First, this system offers the possibility of adapting the main features of the time–voltage profile generated (dip depth, dip duration, the ramp slope during the recovery process after clearing fault, etc.) to the specific requirements set forth by the grid operation codes, in accordance with different network electrical systems standards. Second, another remarkable ability of this system is to provide sinusoidal voltage and current wave forms during the overall testing process without the presence of harmonic components. This is made possible by the absence of electronic converters. Finally, the paper includes results and a discussion on the experimental data obtained with the use of a reduced size laboratory prototype that was constructed to validate the operating features of this new device
Team 6: Joint Capability Metamodel-Test-Metamodel Integration with Data Farming
from Scythe : Proceedings and Bulletin of the International Data Farming Community, Issue 2 Workshop 14US adversaries are continuously seeking new ways to
threaten US interests at home and abroad. In order to
counter these threats, now more than ever,
commanders must seek to leverage existing and
emerging joint capabilities effectively in a variety of
unique contexts. Achieving mission effectiveness in
today's joint operational environment demands robust
synergy among a wide array of mission-critical Service
systems and capabilities
Drosophila Embryonic Hemocytes Produce Laminins to Strengthen Migratory Response
The most prominent developmental function attributed to the extracellular matrix (ECM) is cell migration. While cells in culture can produce ECM to migrate, the role of ECM in regulating developmental cell migration is classically viewed as an exogenous matrix presented to the moving cells. In contrast to this view, we show here that Drosophila embryonic hemocytes deposit their own laminins in streak-like structures to migrate efficiently throughout the embryo. With the help of transplantation experiments, live microscopy, and image quantification, we demonstrate that autocrine-produced laminin regulates hemocyte migration by controlling lamellipodia dynamics, stability, and persistence. Proper laminin deposition is regulated by the RabGTPase Rab8, which is highly expressed and required in hemocytes for lamellipodia dynamics and migration. Our results thus support a model in which, during embryogenesis, the Rab8-regulated autocrine deposition of laminin reinforces directional and effective migration by stabilizing cellular protrusions and strengthening otherwise transient adhesion states.</p
Human Amniocytes Are Receptive to Chemically Induced Reprogramming to Pluripotency
Restoring pluripotency using chemical compounds alone would be a major step forward in developing clinical-grade pluripotent stem cells, but this has not yet been reported in human cells. We previously demonstrated that VPA_ AFS cells, human amniocytes cultivated with valproic acid (VPA) acquired functional pluripotency while remaining distinct from human embryonic stem cells (hESCs), questioning the relationship between the modulation of cell fate and molecular regulation of the pluripotency network. Here, we used single-cell analysis and functional assays to reveal that VPA treatment resulted in a homogeneous population of self-renewing non-transformed cells that fulfill the hallmarks of pluripotency, i.e., a short G1 phase, a dependence on glycolytic metabolism, expression of epigenetic modifications on histones 3 and 4, and reactivation of endogenous OCT4 and downstream targets at a lower level than that observed in hESCs. Mechanistic insights into the process of VPA-induced reprogramming revealed that it was dependent on OCT4 promoter activation, which was achieved independently of the PI3K (phosphatidylinositol 3-kinase)/ AKT/ mTOR (mammalian target of rapamycin) pathway or GSK3 beta inhibition but was concomitant with the presence of acetylated histones H3K9 and H3K56, which promote pluripotency. Our data identify, for the first time, the pluripotent transcriptional and molecular signature and metabolic status of human chemically induced pluripotent stem cells
Explanation and Elaboration Document for the STROBE-Vet Statement: Strengthening the Reporting of Observational Studies in Epidemiology—Veterinary Extension
The STROBE (Strengthening the Reporting of Observational Studies in Epidemiology) statement was first published in 2007 and again in 2014. The purpose of the original STROBE was to provide guidance for authors, reviewers and editors to improve the comprehensiveness of reporting; however, STROBE has a unique focus on observational studies. Although much of the guidance provided by the original STROBE document is directly applicable, it was deemed useful to map those statements to veterinary concepts, provide veterinary examples and highlight unique aspects of reporting in veterinary observational studies. Here, we present the examples and explanations for the checklist items included in the STROBE-Vet Statement. Thus, this is a companion document to the STROBE-Vet Statement Methods and process document, which describes the checklist and how it was developed
The constant-velocity highly collimated outflows of the planetary nebula He 2-90
We present high-dispersion echelle spectroscopic observations and a
narrow-band [N II] image of the remarkable jet-like features of He 2-90. They
are detected in the echelle spectra in the H-alpha and [N II] lines but not in
other nebular lines. The [N II]/H-alpha ratio is uniformly high, ~1. The
observed kinematics reveals bipolar collimated outflows in the jet-like
features and shows that the southeast (northwest) component expands towards
(away from) the observer at a remarkably constant line-of-sight velocity,
26.0+-0.5 km/s. The observed expansion velocity and the opening angle of the
jet-like features are used to estimate an inclination angle of ~5 degrees with
respect to the sky plane and a space expansion velocity of ~290 km/s. The
spectrum of the bright central nebula reveals a profusion of Fe lines and
extended wings of the H-alpha line, similar to those seen in symbiotic stars
and some young planetary nebulae that are presumed to host a mass-exchanging
binary system. If this is the case for He 2-90, the constant velocity and
direction of the jets require a very stable dynamic system against precession
and warping.Comment: 8 pages (emulate ApJ), 5 figure, 1 tabl
Comparison of Bond Character in Hydrocarbons and Fullerenes
We present a comparison of the bond polarizabilities for carbon-carbon bonds
in hydrocarbons and fullerenes, using two different models for the fullerene
Raman spectrum and the results of Raman measurements on ethane and ethylene. We
find that the polarizabilities for single bonds in fullerenes and hydrocarbons
compare well, while the double bonds in fullerenes have greater polarizability
than in ethylene.Comment: 7 pages, no figures, uses RevTeX. (To appear in Phys. Rev. B.
An improved model of the Earth's gravitational field: GEM-T1
Goddard Earth Model T1 (GEM-T1), which was developed from an analysis of direct satellite tracking observations, is the first in a new series of such models. GEM-T1 is complete to degree and order 36. It was developed using consistent reference parameters and extensive earth and ocean tidal models. It was simultaneously solved for gravitational and tidal terms, earth orientation parameters, and the orbital parameters of 580 individual satellite arcs. The solution used only satellite tracking data acquired on 17 different satellites and is predominantly based upon the precise laser data taken by third generation systems. In all, 800,000 observations were used. A major improvement in field accuracy was obtained. For marine geodetic applications, long wavelength geoidal modeling is twice as good as in earlier satellite-only GEM models. Orbit determination accuracy has also been substantially advanced over a wide range of satellites that have been tested
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