A Magnified View of the Kinematics and Morphology of RCSGA 032727-132609: Zooming in on a Merger at z=1.7

We present a detailed analysis of multi-wavelength HST/WFC3 imaging and Keck/OSIRIS near-IR AO-assisted integral field spectroscopy for a highly magnified lensed galaxy at z=1.70. This young starburst is representative of UV-selected star-forming galaxies (SFG) at z~2 and contains multiple individual star-forming regions. Due to the lensing magnification, we can resolve spatial scales down to 100pc in the source plane of the galaxy. The velocity field shows disturbed kinematics suggestive of an ongoing interaction, and there is a clear signature of a tidal tail. We constrain the age, reddening, SFR and stellar mass of the star-forming clumps from SED modelling of the WFC3 photometry and measure their H-alpha luminosity, metallicity and outflow properties from the OSIRIS data. With strong star formation driven outflows in four clumps, RCSGA0327 is the first high redshift SFG at stellar mass <10^10 M_sun with spatially resolved stellar winds. We compare the H-alpha luminosities, sizes and dispersions of the star-forming regions to other high-z clumps as well as local giant HII regions and find no evidence for increased clump star formation surface densities in interacting systems, unlike in the local Universe. Spatially resolved SED modelling unveils an established stellar population at the location of the largest clump and a second mass concentration near the edge of the system which is not detected in H-alpha emission. This suggests a picture of an equal-mass mixed major merger, which has not triggered a new burst of star formation or caused a tidal tail in the gas-poor component.Comment: 22 pages, 16 figures, accepted to Ap

Strong Quantum Spin Correlations Observed in Atomic Spin Mixing

We have observed sub-Poissonian spin correlations generated by collisionally induced spin mixing in a spin-1 Bose-Einstein condensate. We measure a quantum noise reduction of -7 dB (-10 dB corrected for detection noise) below the standard quantum limit (SQL) for the corresponding coherent spin states. The spin fluctuations are detected as atom number differences in the spin states using fluorescent imaging that achieves a detection noise floor of 8 atoms per spin component for a probe time of 100 $\mu$s.Comment: 5 pages, 4 figure

Human Capital Investments in Children: A Comparative Analysis of the Role of Parent-Child Shared Time in Selected Countries

Parents invest in their children's human capital in several ways. We investigate the extent to which the levels and composition of parent-child time varies across countries with different welfare regimes: Finland, Germany and the United States. We test the hypothesis of parent-child time as a form of human capital investment in children using a propensity score treatment effects approach that accounts for the possible endogenous nature of time use and human capital investment. Result: There is considerable evidence of welfare regime effects on parent-child shared time. Our results provide mixed support for the hypothesis that non-care related parent-child time is human capital enriching. The strongest support is found in the case of leisure time and eating time.parent-child time, comparative research, welfare regimes, Finland, Germany, USA, treatment effects, propensity score matching

Comparative Analysis Of Zebrafish And Planarian Model Systems For Developmental Neurotoxicity Screens Using An 87-Compound Library

There is a clear need to establish and validate new methodologies to more quickly and efficiently screen chemicals for potential toxic effects, particularly on development. The emergence of alternative animal systems for rapid toxicology screens presents valuable opportunities to evaluate how systems complement each other. In this article, we compare a chemical library of 87-compounds in two such systems, developing zebrafish and freshwater planarians, by screening for developmental neurotoxic effects. We show that the systems’ toxicological profiles are complementary to each other, with zebrafish yielding more detailed morphological endpoints and planarians more behavioral endpoints. Overall, zebrafish was more sensitive to this chemical library, yielding 86/87 hits, compared to 50/87 hits in planarians. The difference in sensitivity could not be attributed to molecular weight, Log Kow or the bioconcentration factor. Of the 87 chemicals, 28 had previously been evaluated in mammalian developmental neuro- (DNT), neuro- or developmental toxicity studies. Of the 28, 20 were hits in the planarian, and 27 were hits in zebrafish. Eighteen of the 28 had previously been identified as DNT hits in mammals and were highly associated with activity in zebrafish and planarian behavioral assays in this study. Only 1 chemical (out of 28) was a false negative in both zebrafish and planarian systems. Differences in endpoint coverage and system sensitivity illustrate the value of a dual systems approach to rapidly query a large chemical-bioactivity space and provide weight-of-evidence for prioritization of chemicals for further testing

Boolean versus continuous dynamics on simple two-gene modules

We investigate the dynamical behavior of simple modules composed of two genes with two or three regulating connections. Continuous dynamics for mRNA and protein concentrations is compared to a Boolean model for gene activity. Using a generalized method, we study within a single framework different continuous models and different types of regulatory functions, and establish conditions under which the system can display stable oscillations. These conditions concern the time scales, the degree of cooperativity of the regulating interactions, and the signs of the interactions. Not all models that show oscillations under Boolean dynamics can have oscillations under continuous dynamics, and vice versa.Comment: 8 pages, 10 figure

Solid fuel use and cooking practices as a major risk factor for ALRI mortality among African children

Background: Almost half of global child deaths due to acute lower respiratory infections (ALRIs) occur in sub-Saharan Africa, where three-quarters of the population cook with solid fuels. This study aims to quantify the impact of fuel type and cooking practices on childhood ALRI mortality in Africa, and to explore implications for public health interventions. Methods: Early-release World Health Survey data for the year 2003 were pooled for 16 African countries. Among 32 620 children born during the last 10 years, 1455 (4.46%) were reported to have died prior to their fifth birthday. Survival analysis was used to examine the impact of different cooking-related parameters on ALRI mortality, defined as cough accompanied by rapid breathing or chest indrawing based on maternal recall of symptoms prior to death. Results: Solid fuel use increases the risk of ALRI mortality with an adjusted hazard ratio of 2.35 (95% CI 1.22 to 4.52); this association grows stronger with increasing outcome specificity. Differences between households burning solid fuels on a well-ventilated stove and households relying on cleaner fuels are limited. In contrast, cooking with solid fuels in the absence of a chimney or hood is associated with an adjusted hazard ratio of 2.68 (1.38 to 5.23). Outdoor cooking is less harmful than indoor cooking but, overall, stove ventilation emerges as a more significant determinant of ALRI mortality. Conclusions: This study shows substantial differences in ALRI mortality risk among African children in relation to cooking practices, and suggests that stove ventilation may be an important means of reducing indoor air pollution

The Health of Aging Lesbian, Gay and Bisexual Adults in California

Examines rates of diabetes, hypertension, poor mental health, physical disability, and fair or poor self-reported health status among homosexual adults ages 50 to 70 compared with their heterosexual peers. Recommends enhancing policies and practices

Do Newton's G and Milgrom's a_0 vary with cosmological epoch ?

In the scalar tensor gravitational theories Newton's constant G_N evolves in the expanding universe. Likewise, it has been speculated that the acceleration scale a_0 in Milgrom's modified Newtonian dynamics (MOND) is tied to the scale of the cosmos, and must thus evolve. With the advent of relativistic implementations of the modified dynamics, one can address the issue of variability of the two gravitational ''constants'' with some confidence. Using TeVeS, the Tensor-Vector-Scalar gravitational theory, as an implementation of MOND, we calculate the dependence of G_N and a_0 on the TeVeS parameters and the coeval cosmological value of its scalar field, \phi_c. We find that G_N, when expressed in atomic units, is strictly nonevolving, a result fully consistent with recent empirical limits on the variation of G_N. By contrast, we find that a_0 depends on \phi_c and may thus vary with cosmological epoch. However, for the brand of TeVeS which seems most promising, a_0 variation occurs on a timescale much longer than Hubble's, and should be imperceptible back to redshift unity or even beyond it. This is consistent with emergent data on the rotation curves of disk galaxies at significants redshifts.Comment: 9 pages, RevTe

Greater response variability in adolescents is associated with increased white matter development.

Adolescence is a period of learning, exploration, and continuous adaptation to fluctuating environments. Response variability during adolescence is an important, understudied, and developmentally appropriate behavior. The purpose of this study was to identify the association between performance on a dynamic risky decision making task and white matter microstructure in a sample of 48 adolescents (14-16 years). Individuals with the greatest response variability on the task obtained the widest range of experience with potential outcomes to risky choice. When compared with their more behaviorally consistent peers, adolescents with greater response variability rated real-world examples of risk taking behaviors as less risky via self-report. Tract-Based Spatial Statistics (TBSS) were used to examine fractional anisotropy (FA) and mean diffusivity (MD). Greater FA in long-range, late-maturing tracts was associated with higher response variability. Greater FA and lower MD were associated with lower riskiness ratings of real-world risky behaviors. Results suggest that response variability and lower perceived risk attitudes of real-world risk are supported by neural maturation in adolescents