51 research outputs found
Engaging Sources: Information Literacy and theFreshman Research Paper (Part II)
The colonization of Ireland by mammals, has been the subject of extensive study using genetic methods, and forms a central problem in understanding the phylo-geography of European mammals after the Last Glacial Maximum. Ireland exhibits a de-pauperate mammal fauna relative to Great Britain and continental Europe, and a range of natural and anthropogenic processes have given rise to its modern fauna. Previous Europe-wide surveys of the European badger (Meles meles) have found conflicting microsatellite and mitochondrial DNA evidence in Irish populations, suggesting Irish badgers have arisen from admixture between human imported British and Scandinavian animals. . The extent and history of contact between British and Irish badger populations remains unclear. We use comprehensive genetic data from Great Britain and Ireland to demonstrate that badgers in Irelandâs northeastern and southeastern counties are genetically similar to contemporary British populations. Simulation analyses suggest this admixed population arose in Ireland 600-700 (CI 100-2600) years before present most likely through introduction of British badgers by people. These findings add to our knowledge of the complex colonization history of Ireland by mammals, and the central role of humans in facilitating it
âWhoâs been a good dog?â: owner perceptions and motivations for treat giving
Complex relationships commonly exist between owners and their companion animals, particularly around feeding behaviour with an ownerâs affection or love for their animal most pronounced through the provision of food. It is notable that the pet food market is experiencing strong year-on-year growth in sales of dog and cat treats. Recognising the impact of treat giving in pet nutrition, the objective of the study was to investigate owner attitudes and motivations towards feeding treats (shop bought and other) to their dogs. A researcher-mediated questionnaire consisting of both quantitative and qualitative questions was used to interview dog owners (n = 280) at two locations: an out-of-town retail park and a country park in the East Midlands. Owners almost unanimously viewed the word âtreatâ within a nutritional context, as opposed to a new toy or other pleasure. The majority (96%) of owners interviewed reported feeding treats to their dog, with 69% feeding shop-bought treats on a daily basis. A wide range of treats was reportedly given by owners and the majority of owners interviewed fed multiple treat types. No association was found between owner age and frequency of shop-bought treats fed (P = 0.659) nor between owner age and frequency of food given to the dog from the ownerâs plate (P = 0.083). A wide range of foods which would not be considered balanced for the animalâs nutritional requirements was viewed as a treat by some dog owners. A range of positive and negative views around the feeding of treats were expressed by dog owners, with some citing beneficial effects while others were clearly aware of the association between treat feeding and potential weight gain/obesity. Owner views included themes around positive reinforcement and responsibility but also reflected relational aspects of the human-animal bond. The results of the study show that treat giving is commonplace in feeding regimes and that treats are embedded in the feeding behaviour of many dog owners. However, the different views expressed around the motivations for, and feeding of, dog treats, reinforce the need to better understand owner psychology linked to this area, and the role this may play in the growing pet obesity epidemic
Genetic evidence further elucidates the history and extent of badger introductions from Great Britain into Ireland
This is the final version. Available from Royal Society via the DOI in this record.âŻThe colonization of Ireland by mammals has been the subject of extensive study using genetic methods and forms a central problem in understanding the phylogeography of European mammals after the Last Glacial Maximum. Ireland exhibits a depauperate mammal fauna relative to Great Britain and continental Europe, and a range of natural and anthropogenic processes have given rise to its modern fauna. Previous Europe-wide surveys of the European badger (Meles meles) have found conflicting microsatellite and mitochondrial DNA evidence in Irish populations, suggesting Irish badgers have arisen from admixture between human imported British and Scandinavian animals. The extent and history of contact between British and Irish badger populations remains unclear. We use comprehensive genetic data from Great Britain and Ireland to demonstrate that badgers in Ireland's northeastern and southeastern counties are genetically similar to contemporary British populations. Simulation analyses suggest this admixed population arose in Ireland 600-700 (CI 100-2600) years before present most likely through introduction of British badgers by people. These findings add to our knowledge of the complex colonization history of Ireland by mammals and the central role of humans in facilitating it.DAERA-NINER
The IDENTIFY study: the investigation and detection of urological neoplasia in patients referred with suspected urinary tract cancer - a multicentre observational study
Objective
To evaluate the contemporary prevalence of urinary tract cancer (bladder cancer, upper tract urothelial cancer [UTUC] and renal cancer) in patients referred to secondary care with haematuria, adjusted for established patient risk markers and geographical variation.
Patients and Methods
This was an international multicentre prospective observational study. We included patients aged â„16 years, referred to secondary care with suspected urinary tract cancer. Patients with a known or previous urological malignancy were excluded. We estimated the prevalence of bladder cancer, UTUC, renal cancer and prostate cancer; stratified by age, type of haematuria, sex, and smoking. We used a multivariable mixed-effects logistic regression to adjust cancer prevalence for age, type of haematuria, sex, smoking, hospitals, and countries.
Results
Of the 11 059 patients assessed for eligibility, 10 896 were included from 110 hospitals across 26 countries. The overall adjusted cancer prevalence (n = 2257) was 28.2% (95% confidence interval [CI] 22.3â34.1), bladder cancer (n = 1951) 24.7% (95% CI 19.1â30.2), UTUC (n = 128) 1.14% (95% CI 0.77â1.52), renal cancer (n = 107) 1.05% (95% CI 0.80â1.29), and prostate cancer (n = 124) 1.75% (95% CI 1.32â2.18). The odds ratios for patient risk markers in the model for all cancers were: age 1.04 (95% CI 1.03â1.05; P < 0.001), visible haematuria 3.47 (95% CI 2.90â4.15; P < 0.001), male sex 1.30 (95% CI 1.14â1.50; P < 0.001), and smoking 2.70 (95% CI 2.30â3.18; P < 0.001).
Conclusions
A better understanding of cancer prevalence across an international population is required to inform clinical guidelines. We are the first to report urinary tract cancer prevalence across an international population in patients referred to secondary care, adjusted for patient risk markers and geographical variation. Bladder cancer was the most prevalent disease. Visible haematuria was the strongest predictor for urinary tract cancer
The fuel handling route of astrid at the beginning of the basic design
International audienceAt the beginning of the Basic Design phases of ASTRID starting in 2016, the entire fuel handling route has been challenged in order to improve some aspects like availability and investment cost. Especially, studies performed at the end of preliminary design (2010 â 2015) phase show that the availability target will be difficult to obtain with a significant risk of malfunction because of multiple handling operations in series. Two main changes have been then decided: the implementation of an in-sodium external buffer zone, similar with an insodium external storage but associated with an in-primary vessel storage to reduce its size and its allowable residual power, and the merging of the fresh subassembly storage with the spent fuel subassembly storage which allows both reduction of size and number of equipment. These new options have the first advantages to reduce drastically the number of operations that have to be done during scheduled outage and to minimize the overall Balance Of Plant. After description of the entire fuel handling route adopted for ASTRID, this paper aims at identifying the advantages of this new option and points the remaining issues or questions that will be studied in details during the current Basic Design phase
An investigation into the epidemiology of feline obesity in Great Britain: results of a cross-sectional study of 47 companion animal practises
Previous epidemiological studies of feline obesity have been restricted to small geographical areas of Great Britain. This study represents the first published description of the prevalence and risk factors for obesity from a nationally distributed population of cats. Data were gathered from 3227 cats through 47 primary companion animal veterinary practises. The overall prevalence of overweight/obesity was 11.5 per cent (95% confidence interval 10.4 per cent to 12.6 per cent) in cats attending the charity's clinics. Cats in Scotland appeared to have a greater age and neutered-adjusted prevalence compared with cats in England. Neutered status, being male and middle age (around 7â
years), were all significant risk factors for feline overweight/obesity, although they did not fully explain an individual cat's risk of overweight/obesity. Breed was not found to be a statistically significant risk factor. Partial attributable fractions were calculated from each of the significant risk factors. Neutered status appeared to contribute the most to the prevalence of obesity, followed by prime/mature lifestage (3â10â
years of age). Any interpretations of these findings should take into account the multitude of biases inherent in this study. Nevertheless, weight management following neutering appears to be very important to reduce the overall prevalence of overweight/obesity in this population of cats
Exploring the Epidemiology of Canine and Feline Overweight/Obesity in the United Kingdom Using a National Database of Veterinary Practices
No abstract available
Preliminary investigation to establish prevalence and risk factors for being overweight in pet rabbits in Great Britain
- âŠ