199 research outputs found

    Taller paralelo de regeneración urbana DUyOT-DUSP: Innovación docente e internacionalización de la enseñanza

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    Artículo escrito con Ester Higueras y Nagore Urrutia sobre el Taller paralelo de regeneración urbana organizado entre el Master del DUyOT (UPM) y el del DUSP (MIT

    Cities4ZERO: Overcoming Carbon Lock-in in Municipalities through Smart Urban Transformation Processes

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    How can local authorities effectively address the decarbonization of urban environments in the long run? How would their interests and expertise be aligned into an integrated approach towards decarbonization? This paper delves into how strategic processes can help to integrate diverse disciplines and stakeholders when facing urban decarbonization and presents Cities4ZERO, a step-by-step methodology for local authorities, able to guide them through the process of developing the most appropriate plans and projects for an effective urban transition; all from an integrated, participatory and cross-cutting planning approach. For the development of the Cities4ZERO methodology, plans, projects, and strategic processes from five European cities that are part of the Smart Cities and Communities European Commission program have been monitored for 4 years, in close collaboration with local authorities, analyzing ad-hoc local strategic approaches to determine key success factors and barriers to be considered from their transitioning experiences. The study indicates that an iterative strategic approach and a project-oriented vision, combined with a stable institutional commitment, are opening a window of opportunity for cities to achieve effective decarbonization.This research was funded by the European Commission, grant number 691,883

    Towards an Integrated Approach to Urban Decarbonisation in Practice: The Case of Vitoria-Gasteiz

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    How can local authorities effectively approach the decarbonisation of urban environments? Recent efforts to redirect cities into a less energy-intensive model have been mostly approached from a sectoral perspective, with specific energy policies and plans being issued without deeply considering their ties with other urban aspects. In this sense, well-established urban planning procedures have not been part of those, with the consequence of barriers in the implementation phase of those energy plans. The Cities4ZERO methodology was developed to guide effective integration between urban planning and energy policies, plans, and practices. It provides a holistic approach to strategic municipal processes for urban decarbonisation in the mid-long term, which includes key local stakeholders’ engagement into integrated energy planning processes, as well as tools for effective energy decarbonisation modelling. This paper analyses the application of the Cities4ZERO decarbonisation methodology on its strategic stage in the development of Vitoria-Gasteiz’s Action Plan for an Integrated Energy Transition 2030 (APIET 2030). It suggests that in order to accelerate urban decarbonisation, it is critical to: (a) foster interdepartmental collaboration; (b) allow for flexibility on the land-use planning regulations; (c) back decisions with detailed urban-energy models; and (d) truly engage key local stakeholders in the planning and implementation processes.European Commission for funding SmartEnCity project, the frame of this research, and Basque Government for its significant support to the Basque research and innovation paradigm

    ENER-BI: Integrating Energy and Spatial Data for Cities’ Decarbonisation Planning

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    Given the current climate emergency, our planet is suffering. Mitigation measures must be urgently deployed in urban environments, which are responsible for more than 70% of global CO2 emissions. In this sense, a deeper integration between energy and urban planning disciplines is a key factor for effective decarbonisation in urban environments. This is addressed in the Cities4ZERO decarbonisation methodology. This method specifically points out the need for technology-based solutions able to support that integration among both disciplines at a local level, enriching decision-making in urban decarbonisation policy-making, diagnosis, planning, and follow-up tasks, incorporating the spatial dimension to the whole process (GIS-based), as well as the possibilities of the digital era. Accordingly, this paper explores the demands of both integrated urban energy planning and European/Basque energy directives, to set the main requisites and functionalities that Decision Support Systems (DSSs) must fulfil to effectively support city managers and the urban decarbonisation process.This research was funded by European Commission, grant number 691883

    ENER-BI: Integrating Energy and Spatial Data for Cities’ Decarbonisation Planning

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    Given the current climate emergency, our planet is suffering. Mitigation measures must be urgently deployed in urban environments, which are responsible for more than 70% of global CO2 emissions. In this sense, a deeper integration between energy and urban planning disciplines is a key factor for effective decarbonisation in urban environments. This is addressed in the Cities4ZERO decarbonisation methodology. This method specifically points out the need for technology-based solutions able to support that integration among both disciplines at a local level, enriching decision-making in urban decarbonisation policy-making, diagnosis, planning, and follow-up tasks, incorporating the spatial dimension to the whole process (GIS-based), as well as the possibilities of the digital era. Accordingly, this paper explores the demands of both integrated urban energy planning and European/Basque energy directives, to set the main requisites and functionalities that Decision Support Systems (DSSs) must fulfil to effectively support city managers and the urban decarbonisation process.This research was funded by European Commission, grant number 691883

    Desenvolvimento Cognitivo e Afetivo dos estudantes de Contabilidade – influência do Método de Caso à luz da Taxonomia de Bloom

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    Objetivo: avaliar o desenvolvimento cognitivo e afetivo alcançado com a técnica de ensino de método de caso, com base na Taxonomia de Bloom em estudantes do curso de Ciências Contábeis de uma Instituição Federal de Ensino Superior. Método: quase-experimento em grupo de alunos (intacto sem seleção), na disciplina de Estrutura das Demonstrações Contábeis do 4ª semestre, durante o primeiro semestre de 2018. Resultados: revelam que a utilização de uma técnica de ensino ativa, como um instrumento complementar, possui a capacidade de influenciar no nível de desenvolvimento cognitivo e afetivo alcançado pelos estudantes, estimulando também, a tomada de decisão, comunicação e a resolução de problemas, além de propiciar um ambiente de aprendizagem mais interativo, dinâmico, reflexivo e motivador, tornando os estudantes responsáveis pela própria aprendizagem, proporcionando assim, ação e interação do sujeito com o seu objeto de estudo, elementos essenciais e pertinentes para a construção de conhecimento. Contribuições: os dados levantados nesta pesquisa permitem inferir que o uso do método de caso, como técnica complementar de ensino, contribuiu com o desenvolvimento da aprendizagem superficial, pois ampliou o nível de desenvolvimento mais básico, além de auxiliar na ampliação de todos os níveis cognitivos de forma parcial e proporcionar a motivação nos estudantes

    Effect of 15 BMI-Associated polymorphisms, reported for europeans, across ethnicities and degrees of amerindian ancestry in mexican children

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    In Mexico, the genetic mechanisms underlying childhood obesity are poorly known. We evaluated the effect of loci, known to be associated with childhood body mass index (BMI) in Europeans, in Mexican children from different ethnic groups. We performed linear and logistic analyses of BMI and obesity, respectively, in Mestizos and Amerindians (Seris, Yaquis and Nahuatl speakers) from Northern (n = 369) and Central Mexico (n = 8545). We used linear models to understand the effect of degree of Amerindian ancestry (AMA) and genetic risk score (GRS) on BMI z-score. Northern Mexican Mestizos showed the highest overweight-obesity prevalence (47.4%), followed by Seri (36.2%) and Central Mexican (31.5%) children. Eleven loci (SEC16B/rs543874, OLFM4/rs12429545/rs9568856, FTO/rs9939609, MC4R/rs6567160, GNPDA2/rs13130484, FAIM2/rs7132908, FAM120AOS/rs944990, LMX1B/rs3829849, ADAM23/rs13387838, HOXB5/rs9299) were associated with BMI and seven (SEC16B/rs543874, OLFM4/rs12429545/rs9568856, FTO/rs9939609, MC4R/rs6567160, GNPDA2 rs13130484, LMX1B/rs3829849) were associated with obesity in Central Mexican children. One SNP was associated with obesity in Northern Mexicans and Yaquis (SEC16B/rs543874). We found higher BMI z-score at higher GRS (β = 0.11, p = 0.2 × 10−16) and at lower AMA (β = −0.05, p = 6.8 × 10−7). The GRS interacts with AMA to increase BMI (β = 0.03, p = 6.08 × 10−3). High genetic BMI susceptibility increase the risk of higher BMI, including in Amerindian children

    Effect of multi-component school-based program on body mass index, cardiovascular and diabetes risks in a multi-ethnic study

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    Background: Mexico occupies one of the first places worldwide in childhood obesity. Its Mestizo and Indigenous communities present different levels of westernization which have triggered different epidemiological diseases. We assessed the effects of a multi-component school-based intervention program on obesity, cardiovascular and diabetes risk factors. Methods: A physical activity, health education and parent involvement (PAHEPI) program was developed and applied in six urban (Mestizo ethnic group) and indigenous (Seri and Yaqui ethnic groups) primary schools for 12 weeks. A total of 320 children aged 4–12 years participated in intervention program; 203 under Treatment 1 (PAHEPI program) and 117, only from Mestizo groups, under Treatment 2 (PAHEPI+ school meals). For Body Mass Index (BMI), cardiovascular and diabetes factors, pairwise comparisons of values at baseline and after treatments were done using Wilcoxon signed rank test. Generalized linear models were applied to assess the intervention effect by age, sex and nutritional status in relation to ethnicity and treatment. Results: We observed improvements on BMI in children with overweight-obesity and in triglycerides in the three ethnic groups. The Mestizo ethnic group showed the largest improvements under Treatment 2. While Seris showed improvements only in cardiovascular risk factors, Yaquis also showed improvements in diabetes risk factors, though not in BMI. Conclusions: This study showed that the same intervention may have positive but different effects in different ethnic groups depending on their lifestyle and their emerging epidemiological disease. Including this type of intervention as part of the school curriculum would allow to adapt to ethnic group in order to contribute more efficiently to child welfare

    Efficacy and Safety of Reslizumab in Patients with Severe Asthma with Inadequate Response to Omalizumab : A Multicenter, Open-Label Pilot Study

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    Funding: This study was endorsed by the Asthma Research Program of the Spanish Respiratory Society (PII de Asma de SEPAR) supported by a grant from Teva Pharmaceutical Industries.Background: Patients with severe allergic and eosinophilic asthma could qualify for different biologic therapies. Objective: To evaluate the efficacy and safety of weight-based intravenous reslizumab dosing in patients who have previously failed therapy with omalizumab. Methods: We carried out a 24-week prospective, multicenter, open-label, single-group, self-controlled study in patients with severe eosinophilic asthma who had previously failed to respond to omalizumab. The main objective was to determine whether treatment with reslizumab significantly improved asthma symptoms assessed by the Asthma Control Test (ACT) at week 24. Secondary objectives were to evaluate symptoms at weeks 4 and 12, change in FEV at week 24, and the incidence of severe exacerbations over the study period. Results: Twenty-nine patients (62.1% women, median age, 50.8 years) were included in the study. The median ACT score significantly increased from 13.0 (interquartile range, 8.0-18.0) at baseline to 21.0 (interquartile range, 14.0-24.0) at 24 weeks (P =.002). Only 2 of 29 patients developed at least 1 severe exacerbation during follow-up and none of them required hospitalization. Overall, 15 of 25 patients (60%) were considered as being controlled (ACT score of ≥20 and no exacerbations) at week 24. The percentage of patients who were receiving daily systemic corticosteroids significantly decreased from 72.4% to 52.0% (P =.019). Adverse events were mostly moderate and within the range of previously reported side effects with reslizumab. Conclusion: Reslizumab is an effective and safe option for patients with severe eosinophilic asthma and a history of omalizumab failure

    Population Genetics of Franciscana Dolphins (Pontoporia blainvillei): Introducing a New Population from the Southern Edge of Their Distribution

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    Due to anthropogenic factors, the franciscana dolphin, Pontoporia blainvillei, is the most threatened small cetacean on the Atlantic coast of South America. Four Franciscana Management Areas have been proposed: Espiritu Santo to Rio de Janeiro (FMA I), São Paulo to Santa Catarina (FMA II), Rio Grande do Sul to Uruguay (FMA III), and Argentina (FMA IV). Further genetic studies distinguished additional populations within these FMAs. We analyzed the population structure, phylogeography, and demographic history in the southernmost portion of the species range. From the analysis of mitochondrial DNA control region sequences, 5 novel haplotypes were found, totalizing 60 haplotypes for the entire distribution range. The haplotype network did not show an apparent phylogeographical signal for the southern FMAs. Two populations were identified: Monte Hermoso (MH) and Necochea (NC)+Claromecó (CL)+Río Negro (RN). The low levels of genetic variability, the relative constant size over time, and the low levels of gene flow may indicate that MH has been colonized by a few maternal lineages and became isolated from geographically close populations. The apparent increase in NC+CL+RN size would be consistent with the higher genetic variability found, since genetic diversity is generally higher in older and expanding populations. Additionally, RN may have experienced a recent split from CL and NC; current high levels of gene flow may be occurring between the latter ones. FMA IV would comprise four franciscana dolphin populations: Samborombón West+Samborombón South, Cabo San Antonio+Buenos Aires East, NC+CL+Buenos Aires Southwest+RN and MH. Results achieved in this study need to be taken into account in order to ensure the long-term survival of the species.Fil: Gariboldi, María Constanza. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Maimónides. Área de Investigaciones Biomédicas y Biotecnológicas. Centro de Estudios Biomédicos, Biotecnológicos, Ambientales y de Diagnóstico; ArgentinaFil: Tunez, Juan Ignacio. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Luján; ArgentinaFil: Dejean, Cristina Beatriz. Universidad Maimónides. Área de Investigaciones Biomédicas y Biotecnológicas. Centro de Estudios Biomédicos, Biotecnológicos, Ambientales y de Diagnóstico; Argentina. Universidad de Buenos Aires. Facultad de Filosofía y Letras. Instituto de Ciencias Antropológicas. Sección Antropología Biológica; ArgentinaFil: Failla, Mauricio. Fundación Cethus; ArgentinaFil: Vitullo, Alfredo Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Maimónides. Área de Investigaciones Biomédicas y Biotecnológicas. Centro de Estudios Biomédicos, Biotecnológicos, Ambientales y de Diagnóstico; ArgentinaFil: Negri, Maria Fernanda. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Museo Argentino de Ciencias Naturales ; ArgentinaFil: Cappozzo, Humberto Luis. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Maimónides. Área de Investigaciones Biomédicas y Biotecnológicas. Centro de Estudios Biomédicos, Biotecnológicos, Ambientales y de Diagnóstico; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Museo Argentino de Ciencias Naturales ; Argentin
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