Assessment of coronary artery outward remodeling in consequence of excision of epicardial adipose tissue in Ossabaw swine

Background Coronary artery disease (CAD) results from the buildup of cholesterol, inflammatory factors, and proliferating smooth muscle cells within a vessel wall. This plaque impedes on the vessel lumen, decreasing the space through which blood can flow, leading to an array of complications in the human body. To offset these effects, the arterial wall undergoes outward remodeling, a compensatory physiologic phenomenon that blood vessels undertake when burdened with a blockage, such as CAD. In a previously conducted study, a coronary epicardial adipose tissue excision (cEATx) surgery was performed above the left anterior descending (LAD) in Ossabaw swine to investigate the effects of local adipose on the progression of CAD. Compared to the sham control group, pigs that underwent the adipectomy procedure revealed focal attenuation of disease progression at the surgical site within the LAD. Unlike, the previous research question, this current study aims to determine if there was an additional global outward remodeling effect by investigating disease progression in the right coronary artery (RCA) of the same animals. By comparing the two sites, we are able to determine whether the outward remodeling observed in the LAD was due to the local surgical procedure or a physiologic compensation for limitations caused by CAD progression. Methods Images of the RCA lumen were collected using intravascular ultrasound (IVUS). Measurements of the external elastic lamina and lumen area were taken of each collected still-frame image. For each pig, the data were averaged across the proximal 15 mm of the RCA at two separate time points (pre- and post-surgery). Pre-surgery measures were obtained the day the surgery took place while post-surgery measures were obtained 3 months later. Percent stenosis, plaque area, outward remodeling, and lumen area were all assessed. Results Progression of CAD in the RCA, represented by percent stenosis, was not significantly slowed in the adipectomy pigs compared to the control group. Outward remodeling in the RCA, represented by an increase in external elastic lamina circumference, was not significantly higher in the adipectomy pigs compared to the control group. Conclusions These data indicate that the cEATx procedure at the LAD did not attenuate CAD progression in the RCA

Femmes et santé, en français s’il-vous-plaît

Les interventions des groupes de Franco-Ontariennes dans le champ de la santé remontent àla création même de ces groupes. Suite aux transformations qu’a connues la communautéfranco-ontarienne et à la présence accrue de l’intervention de l’État, les groupes de femmes audébut des années 80 ont interrogé le rapport des femmes à la santé. Ainsi, des services pourla communauté et la famille, leurs préoccupations se sont tournées vers elles-mêmes en créantdes formations et en revendiquant des services en français. Plus récemment, de nouvellessensibilités émergent; nouvelle définition de la santé, vision d’ensemble de la condition desFranco-Ontariennes et intégration des préoccupations des femmes des diverses communautésethniques

Pets that learn

Thesis (M.S.V.S.)--Massachusetts Institute of Technology, Dept. of Architecture, 1989.Includes bibliographical references (leaves 41-43).by William H. Coderre.M.S.V.S

A versatile and light-weight slow control system for small-scale applications

We present an open source slow control system for small and medium scale projects. Thanks to its modular and flexible design, where the various instruments are read and controlled by independent plugins, Doberman (Detector OBsERving and Monitoring ApplicatioN) can be quickly adapted for many applications, also making use of existing code or proprietary components. The system uses a SQL database to store the data from the instruments and provides an online application to display and browse through the data. It allows the modification of device settings while the program is running and features a protocol to handle exceptions, including the automated distribution of alarm messages. We present two case studies from astroparticle physics, on which Doberman is successfully deployed: a low-background screening facility installed in a remote underground laboratory and a detector R&D platform using cryogenic liquid xenon

Voracité comparative de trois coccinelles prédatrices contre le tétranyque rouge du pommier [Acarina : Tetranychidae]

La voracité de la coccinelle à sept points, Coccinella septempunctata, de la coccinelle à quatorze points, Propylea quatuordecimpunctata, et de la coccinelle orientale, Harmonia axyridis, [Coleoptera : Coccinellidae] a été évaluée en laboratoire face au tétranyque rouge du pommier, Panonychus ulmi [Acarina : Tetranychidae]. Les trois espèces ont consommé le tétranyque rouge. H. axyridis était significativement plus vorace que les autres espèces et présente le potentiel le plus élevé comme ennemi naturel du tétranyque. Malgré sa grande taille, C. septempunctata possédait une voracité très faible, ce qui confirme son inefficacité comme agent de lutte face aux acariens phytophages.Voracity of the seven-spotted ladybeetle, Coccinella septempunctata, the fourteen-spotted ladybeetle, Propylea quatuordecimpunctata, and the oriental ladybeetle, Harmonia axyridis [Coleoptera : Coccinellidae], was evaluated in laboratory on the European red mite, Panonychus ulmi [Acarina : Tetranychidae]. The three species fed on the European red mite. H. axyridis was significantly more voracious than the other species and has the greater potential as a natural enemy of the mite. Despite its large size, C. septempunctata showed a very low voracity, confirming its inefficacy as a biological control agent against phytophagous mites

Influence of prey quality on the reproductive capacity of two phenotypes of Harmonia axyridis PALLAS (Coleoptera: Coccinelidae).

Proceedings of the 8th International Symposium on Ecology of Aphidophaga : Biology, Ecology and Behaviour of Aphidophagous Insects, Ponta Delgada 1-6 September 2002.H. axyridis is a highly polymorphic ladybird beetle with a wide geographical distribution in the palearctic region. Genetic polymorphism seems to be the strategy adopted in order to face different habitats at different times. In this paper we suggest that a genotype that confers a specific elytral pattern may also confer a particular reproductive capacity when fed on single diets of essential preys such as A. fabae or M. persicae. We discuss KOMAI & HOSINO (1951) hypothesis, which predicts that the differences in the relative frequency of elytral pattern phenotypes in relation to the host plants in a same habitat could be related with specific composition of aphid populations. Our results revealed that A. fabae significantly increased reproductive capacity of nigra phenotype without affecting reproductive capacity of aulica phenotype