Supervisor Self-disclosure: Supervisees\u27 Experiences and Perspectives

Twelve graduate-level supervisees were interviewed regarding their experiences of supervisor self-disclosure (SRSD); data were analyzed using consensual qualitative research. When describing a specific SRSD experience, supervisees reported a range of antecedents (e.g., difficult clinical situation, self-doubt, tension in supervision relationship) followed by supervisor disclosures about clinical experiences or personal information. Supervisees perceived that their supervisors disclosed primarily to normalize, but also to build rapport and to instruct. The SRSDs had mostly positive effects (e.g., normalization), though some negative effects (e.g., deleterious impact on supervision relationship) were reported. Implications of these findings for supervision, training, and research are addressed

The regulation of matrix metalloproteinases and their inhibitors

The matrix metalloproteinases (MMP) are a family of 23 enzymes in man. These enzymes were originally described as cleaving extracellular matrix (ECM) substrates with a predominant role in ECM homeostasis, but it is now clear that they have much wider functionality. Control over MMP and/or tissue inhibitor of metalloproteinases (TIMP) activity in vivo occurs at different levels and involves factors such as regulation of gene expression, activation of zymogens and inhibition of active enzymes by specific inhibitors. Whilst these enzymes and inhibitors have clear roles in physiological tissue turnover and homeostasis, if control of their expression or activity is lost, they contribute to a number of pathologies including e.g. cancer, arthritis and cardiovascular disease. The expression of many MMPs and TIMPs is regulated at the level of transcription by a variety of growth factors, cytokines and chemokines, though post-transcriptional pathways may contribute to this regulation in specific cases. The contribution of epigenetic modifications has also been uncovered in recent years. The promoter regions of many of these genes have been, at least partly, characterised including the role of identified single nucleotide polymorphisms. This article aims to review current knowledge across these gene families and use a bioinformatic approach to fill the gaps where no functional data are available

When I Am Gone, Beloved\u27

Two stands with rose vines surrounding each standhttps://scholarsjunction.msstate.edu/cht-sheet-music/6715/thumbnail.jp

Towards Multispecies Interaction Environments: Extending Accessibility to Canine Users

In this paper we discuss the role of mobility assistance dogs in human society and the challenges they face when operating in human environments. We present the findings of an ethnographic study at a training facility as well as the findings of early evaluations of canine-friendly switches. We discuss how the species-specific implementation of core interaction design principles could inform the design of interaction environments that better support these skilled workers

Characterization of Attachment and Growth of Thiobacillus denitrificans on Pyrite Surfaces

Anaerobic growth and attachment of the autotrophic denitrifying bacterium Thiobacillus denitrificans on pyrite surfaces were studied. Polished pyrite slabs were exposed to T. denitrificans for 1 to 9 weeks. The reacted pyrite surfaces were imaged with scanning electron microscopy (SEM) and confocal laser scanning microscopy (CLSM). Cells were observed as isolated attached cells, cells in division and cells forming microcolonies embedded in organic films. Bacteria began to colonize pyrite surfaces after 1 week, forming microcolonies after 3 weeks. The rate of colonization of the pyrite surface was around 35 cells mm−2 h−1 for the 3-week period. After 9 weeks, larger areas of the pyrite surface were covered by organic films. Bacterial enumeration on the pyrite surface and in solution showed that most of the cells were not attached to the mineral surface. Nevertheless, both attached and free-living bacteria probably contributed to pyrite-driven denitrification. The results may be applied to the natural environment to better understand pyrite-driven denitrification in aquifers and to improve the long-term performance of bioremediation processes using pyrite

A actual crise planetária. Uma dimensão esquecida na educação em ciência

Afinalidade da presente investigação foi analisar qual o possível contributo da Educação em Ciência na clarificação e compreensão pública dos problemas e desafios relacionados com o futuro do nosso planeta. Iniciámos o trabalho procurando o contributo de diferentes estudos elaborados numa perspectiva holística, tendo como objectivo principal elaborar uma visão global do estado do planeta Terra e estudar as possíveis causas e soluções para os problemas identificados. Posteriormente analisámos as percepções de professores de ciências, 327 'em serviço' e 521 'em formação' de Espanha, Portugal e América Latina. Analisámos, ainda, o conteúdo de 127 manuais escolares referentes ao ensino secundário e 3485 artigos publicados entre 1992 e 1998 em Espanha e em revistas internacionais de educação em ciência. Podemos dizer que todos os resultados obtidos mostram semelhanças e, também, indicam, que o estado do Planeta é, ainda, uma dimensão em falta na Educação em Ciência (Biologia, Física, Geologia, Química, ...), devendo ser incorporada com urgência no currículo

The Ursinus Weekly, March 14, 1949

Juniors elect Ruby editors, managers • Judge to consider judicial processes with pre-law group • Shumaker-Saurman Maser-Webb team for 1950 production • Coeds welcome twenty-seven into various sorority circles • ICG to indoctrinate Pa. college students in state legislature • Versatile speaker discusses integration of classical arts • Sweethearts to highlights week-end events • Curtain Club unit presents play to Collegeville community club • Penn faculty re-elects Chandler to board of university museum • Pre-medical meeting to include famed radiologist, cancer film • What do you think of our social activities? • Ursinus finally discovers coefficient of expansion • Ursinus speedsters turn out in force for track sessions • Jaffe, star center, makes conference all-star team • Seeders loses seven Cagers • Wrestling team elects Turner as captain for 1950 campaign • Intramural contests slated for Monday • Belles trounce Penn for seventh victory • Jaffe tops hoop scorers • Matlack named tennis coach; candidates to hold first meeting • Ellis places in two events as swimmers finish fifth • Variety of ballads captivates audience at \u27Lantern\u27 benefithttps://digitalcommons.ursinus.edu/weekly/1611/thumbnail.jp

The Global Burden of Perinatal Common Mental Disorders and Substance Use Amongst Migrant Women:A Systematic Review and Meta-Analysis

BACKGROUND: There are one billion migrants globally, of whom 82 million are forced migrants. Pregnant migrants face pre-migration stressors such as conflict, transit stressors including poverty, and post-migration stressors including navigating the immigration system; these stressors can make them vulnerable to mental illness. We aimed to assess the global prevalence of and risk factors for perinatal mental health disorders or substance use among women who are migrants. METHODS: In this systematic review and meta-analysis, we searched OVID MEDLINE, Embase, PsycINFO, CENTRAL, Global Health, Scopus, and Web of Science for studies published from database inception until July 8, 2022. Cohort, cross-sectional, and interventional studies with prevalence data for any mental illness in pregnancy or the postnatal period (ie, up to a year after delivery) or substance use in pregnancy were included. The primary outcome was the prevalence of perinatal common mental health disorders among women who are migrants, globally. Data for study quality and risk factors were also extracted. A random-effects meta-analysis was used to calculate pooled prevalence estimates, when appropriate. Sensitivity analyses were conducted according to study quality, sample representativeness, and method of outcome assessment. Risk factor data were synthesised narratively. This study is registered with PROSPERO, CRD42021226291. FINDINGS: 18 650 studies were retrieved, of which 135 studies comprising data from 621 995 participants met the inclusion criteria. 123 (91%) of 135 studies were conducted in high-income host countries. Five (4%) of 135 studies were interventional, 40 (30%) were cohort, and 90 (66%) were cross-sectional. The most common regions of origin of participants were South America, the Middle East, and north Africa. Only 26 studies presented disaggregated data for forced migrants or economic migrants. The pooled prevalence of perinatal depressive disorders was 24·2% (range 0·5-95·5%; I2 98·8%; τ2 0·01) among all women who are migrants, 32·5% (1·5-81·6; 98·7%; 0·01) among forced migrants, and 13·7% (4·7-35·1; 91·5%; 0·01) among economic migrants (p<0·001). The pooled prevalence of perinatal anxiety disorders was 19·6% (range 1·2-53·1; I2 96·8%; τ2 0·01) among all migrants. The pooled prevalence of perinatal post-traumatic stress disorder (PTSD) among all migrant women was 8·9% (range 3·2-33·3; I2 97·4%; τ2 0·18). The pooled prevalence of perinatal PTSD among forced migrants was 17·1% (range 6·5-44·3; I2 96·6%; τ2 0·32). Key risk factors for perinatal depression were being a recently arrived immigrant (ie, approximately within the past year), having poor social support, and having a poor relationship with one's partner. INTERPRETATION: One in four women who are migrants and who are pregnant or post partum experience perinatal depression, one in five perinatal anxiety, and one in 11 perinatal PTSD. The burden of perinatal mental illness appears higher among women who are forced migrants compared with women who are economic migrants. To our knowledge, we have provided the first pooled estimate of perinatal depression and PTSD among women who are forced migrants. Interpreting the prevalence estimate should be observed with caution due to the very wide range found within the included studies. Additionally, 66% of studies were cross-sectional representing low quality evidence. These findings highlight the need for community-based routine perinatal mental health screening for migrant communities, and access to interventions that are culturally sensitive, particularly for forced migrants who might experience a higher burden of disease than economic migrants. FUNDING: UK National Institute for Health Research (NIHR); March of Dimes European Preterm Birth Research Centre, Imperial College; Imperial College NIHR Biomedical Research Centre; and Nuffield Department of Population Health, University of Oxford