5,455 research outputs found

    Some Identities on the High-Order -Euler Numbers and Polynomials with Weight 0

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    We construct the th order nonlinear ordinary differential equation related to the generating function of -Euler numbers with weight 0. From this, we derive some identities on -Euler numbers and polynomials of higher order with weight 0

    Increased Prevalence of low High-density Lipoprotein Cholesterol (HDL-C) Levels in Korean Adults: Analysis of the Three Korean National Health and Nutrition Examination Surveys (KNHANES 1998–2005)

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    AbstractObjectivesHigh-density lipoprotein cholesterol (HDL-C) is an independent risk factor for cardiovascular diseases that has shown a remarkable increase, but little is known about the prevalence of low HDL-C in Korea. This study aimed to evaluate changing trends of low HDL-C prevalence, and indicate other risk factors associated with low HDL-C.MethodsWe selected subjects aged ≥20 years from the Korean National Health and Nutrition Examination Survey (KNHANES) 1998, 2001, and 2005 (n = 7962, 6436, and 6412). The mean level of HDL-C and the prevalence of low HDL-C was calculated, and cardiovascular risk factors associated with low HDL-C, as well as demographic, anthropometric, lifestyle, and nutrition factors, were assessed using the KNHANES 2005 data.ResultsMean HDL-C levels in men and women between KNHANES 1998 and 2005 decreased significantly, from 48.1 to 42.3 and from 51.6 to 47.1 mg/dL, respectively (both p < 0.001). The decrease was slightly less for women compared with men for the same period, and women had higher HDL-C levels at all periods. Covariate-adjusted OR revealed that body mass index, waist circumference, and non-alcohol drinker in both men and women were associated with low HDL-C levels by KNHANES 2005, as were employed and light physical activity in men and low fat intake in women.ConclusionThe prevalence of low HDL-C increased significantly from KNHANES 1998 to 2001 and 2005 (p < 0.001) in both men and women. body mass index, waist circumference, and non-alcohol drinker were identified as associated with low HDL-C in Korean adults

    Comparisons of ELISA and Western blot assays for detection of autophagy flux

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    We analyzed autophagy/mitophagy flux in vitro (C2C12 myotubes) and in vivo (mouse skeletal muscle) following the treatments of autophagy inducers (starvation, rapamycin) and a mitophagy inducer (carbonyl cyanide m-chlorophenylhydrazone, CCCP) using two immunodetection methods, ELISA and Western blotting, and compared their working range, accuracy, and reliability. The ELISAs showed a broader working range than that of the LC3 Western blots (Table 1). Table 2 showed that data value distribution was tighter and the average standard error from the ELISA was much smaller than those of the Western blot, directly relating to the accuracy of the assay. Test-retest reliability analysis showed good reliability for three individual ELISAs (interclass correlation, ≥ 0.7), but poor reliability for three individual Western blots (interclass correlation, ≤ 0.4) (Table 3). Keywords: Autophagy, Mitophagy, ELISA, Western blot, Skeletal muscl

    Sorokdo: From the Island of Stigma to the Island of Historical Reflection

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    This article focuses on Sorokdo Island (Jeollanam-do, South Korea) as a remnant of the stigmatized landscape reflecting Hansen’s Disease and the Japanese colonial power. Sorokdo began to be stigmatized due to the Japanese colonial rule in the early 20th century when patients with Hansen\u27s Disease were forced to relocate there, suffering from human rights violations and labor exploitation. Isolation and the management of the patients by suppression and control were justified with the logic of modern values of sanitization supported by the colonial rule. Stigma has remained even after the liberation from the colonial power. Continuously recognized by people as an isolated, remote island with a significant concentration of patients with Hansen’s Disease, Sorokdo still is being poorly preserved and overlooked by the public and the government. Based on a literature review and field research, this article illustrates how stigmatized landscapes remain in the hospital, detention/testing rooms, the Japanese Shinto shrine, and Central Park, among others. This article points out the necessity to preserve the landscape so that Sorokdo can be used as a space to educate and reflect on history. The suppression of the patients and workers on this island also should be illuminated. This article further emphasizes that social consensus is required regarding how Sorokdo can be carefully managed as a place that reflects its traumatized colonial history

    Improvement in the hygroscopicity of inorganic binder through a dual coating process

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    The use of an anti-absorbent is proposed in this work to reduce the hygroscopicity of the inorganic binder in the casting mold, in which the anti-absorbent is coated on the mold prepared with an inorganic binder. Three types of polymers were used to select material with optimal water resistance. Polystyrene (PS) and polyvinyl alcohol (PVA) were used as a water-insoluble polymer and water-soluble polymer, respectively. In addition, polyurethane (PU) prepolymer has intermediate properties between PS and PVA. PVA and PU prepolymer were used for comparative testing with PS. For this testing process, the prepared green body was dipped into a solution of inorganic binder precursor mixed with tetraethyl orthosilicate (TEOS, SiO2 precursor) and sodium methoxide (NaOMe, Na2O precursor), and then dipped into a solution of coating reagent after a drying process. Thus, these series of coating processes in a green body is called a dual coating process. Finally the sample was heat-treated at 1000 °C to generate a glass phase by an organic–inorganic conversion process. In the sample prepared with PS, the highest contact angle and a high firing strength were exhibited, independent of polymer concentration, while the sample coated with PVA showed lower green and firing strengths. When prepolymer, PU, was applied, the green strength was remarkably improved, showing lower firing strength compared with that of PS. The green and firing strengths were optimized through the dual coating process with PS. Moreover, the moisture-proof effect of the dual coating process was verified through the moisture steam test

    Prevalence of sarcopenia and sarcopenic obesity in Korean adults: The Korean Sarcopenic Obesity Study (KSOS)

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    *Context:* Sarcopenic obesity (SO), a combination of excess weight and reduced muscle mass and/or strength, is suggested to be associated with an increased risk of adverse health outcomes. &#xd;&#xa;*Objectives:* To examine the prevalence and characteristics of Sarcopenic and SO defined by using different indices such as Appendicular Skeletal muscle Mass (ASM)/height^2^ and Skeletal Muscle Index (SMI (%): skeletal muscle mass (kg)/weight (kg) &#xd7; 100) for Korean adults. &#xd;&#xa;*Methods:* 591 participants were recruited from the Korean Sarcopenic Obesity Study (KSOS) which is an ongoing prospective observational cohort study. Analysis was conducted in 526 participants (328 women, 198 men) who had complete data on body composition using Dual X-ray absorptiometry and computed tomography. &#xd;&#xa;*Results:* The prevalence of sarcopenia and SO increases with aging. Using two or more standard deviations (SD) of ASM/height^2^ below reference values from young, healthy adults as a definition of sarcopenia, the prevalence of sarcopenia and SO was 6.3% and 1.3% in men and 4.1% and 1.7% in women over 60 years of age. However, using two or more SD of SMI, the prevalence of sarcopenia and SO was 5.1% and 5.1% respectively in men and 14.2% and 12.5% respectively in women. As defined by SMI, subjects with SO had 3 times the risk of metabolic syndrome (OR = 3.03, 95% confidence interval (CI) = 1.26-7.26) and subjects with non-sarcopenic obesity had approximately 2 times the risk of metabolic syndrome (OR = 1.89, 95% CI = 1.18-3.02) compared with normal subjects. &#xd;&#xa;*Conclusion:* Obese subjects with relative sarcopenia were associated with a greater likelihood for metabolic syndrome. As Koreans were more obese and aging, the prevalence of SO and its impact on health outcomes are estimated to be rapidly grow. Further research is requested to establish the definition, cause and consequences of SO.&#xd;&#xa
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