14 research outputs found
L'Ășs d'animals a la medicina de la tradiciĂł llatina: estudi del Tresor de la Beutat, un tractat medieval dedicat als cosmĂštics femenins
LâĂșs de productes derivats dâanimals (ZooterĂ pia) ha format part de lâarsenal terapĂšutic dermatolĂČgic en les diverses cultures a travĂ©s del temps. El Tresor de Beutat Ă©s un tractat medieval dedicat als cosmĂštics femenins i la salut, escrit en catalĂ medieval que es conserva a la Biblioteca de la Universitat de Barcelona. Descriu mĂ©s de 200 remeis i tractaments per a les dones del segle XIV . Molts dâaquests tractaments eren productes dâorigen animal. Estudiem el Tresor de Beutat per determinar quins animals i quines de les seves parts eren emprades, aixĂ com la forma dâutilitzaciĂł i indicacions terapĂšutiques. El document original va ser transcrit al catalĂ formal i el text analitzat per tal dâidentificar totes les substĂ ncies dâorigen animal destinades a la terĂ pia. Aquestes substĂ ncies van ser ordenades segons lâespĂšcie, i es van estudiar les diferents parts emprades dels animals, la manera de preparaciĂł i les seves indicacions.Es van identificar un total de 223 substĂ ncies o elements (animals, plantes i minerals) utilitzats com a remeis. Dâells, 47 (21%) eren dâorigen animal, pertanyents a 30 animals, 15 mamĂfers, 7 aus, 4 animals marins, 2 de rĂšptils i amfibis i 2 insectes. Les diferents parts dels animals utilitzats inclouen la pell, el greix, els ronyons, el cervell, les banyes, les ungles, les secrecions anals, glĂ ndules mamĂ ries o salivals, la femta, o fins i tot lâanimal sencer, en el cas dels mamĂfers. De les aus, sâusaven les plomes, ous, greixos, els nius, el cap, el suc propi de lâanimal, i els excrements. Dels animals marins es va emprar lâanimal a trossos, els ossos i els ous, i dels insectes els ous de formiga; la mel i la cera dâabelles; dels rĂšptils i amfibis els ous i la sang. Els tractaments sâutilitzen principalment per a la cara, com a cosmĂštics per al cabell i el cos, la higiene, la salut general i per la pell. TambĂ© per lâesfera otorinolaringolĂČgica, ocular, els trastorns dentals, i ginecolĂČgics, aixĂ com per a lâalleugeriment del dolor. El Tresor de Beutat proporciona informaciĂł sobre el coneixement dels tractaments tĂČpics, amb una base cientĂfica (i no mĂ gica) amb una Ă mplia gamma de recursos dâorigen animal, amb les formulacions acuradament elaborades per a fins cosmĂštics i terapĂšutics dissenyats per assolir lâideal de la bellesa i la salut en les dones medievals, sent evident en les bases dâalguns tractaments tĂČpics utilitzats en el segle XXI
Intermittent hypoxia is associated with high hypoxia inducible factor-1α but not high vascular endothelial growth factor cell expression in tumors of cutaneous melanoma patients
Epidemiological associations linking between obstructive sleep apnea and poorer solid malignant tumor outcomes have recently emerged. Putative pathways proposed to explain that these associations have included enhanced hypoxia inducible factor (HIF)-1α and vascular endothelial growth factor (VEGF) cell expression in the tumor and altered immune functions via intermittent hypoxia (IH). Here, we examined relationships between HIF-1α and VEGF expression and nocturnal IH in cutaneous melanoma (CM) tumor samples. Prospectively recruited patients with CM tumor samples were included and underwent overnight polygraphy. General clinical features, apnea-hypopnea index (AHI), desaturation index (DI4%), and CM characteristics were recorded. Histochemical assessments of VEGF and HIF-1α were performed, and the percentage of positive cells (0, 75%) was blindly tabulated for VEGF expression, and as 0, 0-5.9, 6.0-10.0, >10.0% for HIF-1α expression, respectively. Cases with HIF-1α expression >6% (high expression) were compared with those 75% of cells was compared with those with <75%. 376 patients were included. High expression of VEGF and HIF-1α were seen in 88.8 and 4.2% of samples, respectively. High expression of VEGF was only associated with increasing age. However, high expression of HIF-1α was significantly associated with age, Breslow index, AHI, and DI4%. Logistic regression showed that DI4% [OR 1.03 (95% CI: 1.01-1.06)] and Breslow index [OR 1.28 (95% CI: 1.18-1.46)], but not AHI, remained independently associated with the presence of high HIF-1α expression. Thus, IH emerges as an independent risk factor for higher HIF-1α expression in CM tumors and is inferentially linked to worse clinical CM prognostic indicators
Medicina mĂ gica a les comarques de la Marina: papers masculins i femenins
La medicina popular consisteix en lâestudi de les tradicions ancestrals i
costums de tipus religiĂłs popular que el poble ha emprat per guarir i previndre
tot tipus de malalties, perque aquest Ă©s un fenomen inseparable de la vida i
totes les societats han fet front a eixe problema. Als paĂŻsos mediterranis i concretament al PaĂs ValenciĂ , la dona ha jugat un paper clau en el manteniment i
pervivĂšncia dâaquestes prĂ ctiques. En el present treball comentem alguns aspectes relacionats amb la medicina
mĂ gico-religiosa quĂš hem pogut comprovar encara sĂłn vius al nostre entorn.
Expliquem alguns remeis mĂ gics com sĂłn trencar els golls, traure el sol del
cap, trencar lâenfit, tractar el mal dâull. TambĂ© analitzem algunes malalties
especĂfiques que es beneficien dâun tractament mĂ gic com sĂłn les berrugues
o el mussol entre altres. Repasem els sants sanadors i, per acabar, comentem
alguns professionals sanitaris que basaven la seua activitat sanadora en rituals
i oraciones mĂ giques.Folk medicine is based upon the study of old traditions, basically of a religious character, that people have used for ages in order to avoid and treat
different illnesses. All societies need to give an answer to the question of illness
because this is an important part of life itself. In the Mediterranean countries,
more specifically in the Pais ValenciĂ , women have played a main role in keeping and transmitting these traditions. In this paper we review different aspects of folk medicine that is still active
nowadays. We explain some magic treatments like trencar els golls, traure el sol
del cap, trencar lâenfit, tractar el mal dâull. We also analyze some specific illness
that responds to a magic treatment like warts or stye. We also analyze different health professionals whose caring practice is based on magic prayers and
activities
Medicina mĂĄgica en las comarcas de la Marina: roles masculinos y femeninos
La medicina popular consisteix en lâestudi de les tradicions ancestrals i
costums de tipus religiĂłs popular que el poble ha emprat per guarir i previndre
tot tipus de malalties, perque aquest Ă©s un fenomen inseparable de la vida i
totes les societats han fet front a eixe problema. Als paĂŻsos mediterranis i concretament al PaĂs ValenciĂ , la dona ha jugat un paper clau en el manteniment i
pervivĂšncia dâaquestes prĂ ctiques. En el present treball comentem alguns aspectes relacionats amb la medicina
mĂ gico-religiosa quĂš hem pogut comprovar encara sĂłn vius al nostre entorn.
Expliquem alguns remeis mĂ gics com sĂłn trencar els golls, traure el sol del
cap, trencar lâenfit, tractar el mal dâull. TambĂ© analitzem algunes malalties
especĂfiques que es beneficien dâun tractament mĂ gic com sĂłn les berrugues
o el mussol entre altres. Repasem els sants sanadors i, per acabar, comentem
alguns professionals sanitaris que basaven la seua activitat sanadora en rituals
i oraciones mĂ giques.Folk medicine is based upon the study of old traditions, basically of a religious character, that people have used for ages in order to avoid and treat
different illnesses. All societies need to give an answer to the question of illness
because this is an important part of life itself. In the Mediterranean countries,
more specifically in the Pais ValenciĂ , women have played a main role in keeping and transmitting these traditions. In this paper we review different aspects of folk medicine that is still active
nowadays. We explain some magic treatments like trencar els golls, traure el sol
del cap, trencar lâenfit, tractar el mal dâull. We also analyze some specific illness
that responds to a magic treatment like warts or stye. We also analyze different health professionals whose caring practice is based on magic prayers and
activities
Terapias respiratorias domiciliarias: innovaciĂłn tecnolĂłgica en la enfermedad pulmonar obstructiva crĂłnica grave
Short and Long-Term Impact of COVID-19 Infection on Previous Respiratory Diseases.
On March 11, 2020, the World Health Organization declared Coronavirus Disease 2019 (COVID-19) a pandemic. Till now, it affected 452.4 million (Spain, 11.18 million) persons all over the world with a total of 6.04 million of deaths (Spain, 100,992). It is observed that 75% of hospitalized COVID-19 patients have at least one COVID-19 associated comorbidity. It was shown that people with underlying chronic illnesses are more likely to get it and grow seriously ill. Individuals with COVID-19 who have a past medical history of cardiovascular disorder, cancer, obesity, chronic lung disease, diabetes, or neurological disease had the worst prognosis and are more likely to develop acute respiratory distress syndrome or pneumonia. COVID-19 can affect the respiratory system in a variety of ways and across a spectrum of levels of disease severity, depending on a person's immune system, age and comorbidities. Symptoms can range from mild, such as cough, shortness of breath and fever, to critical disease, including respiratory failure, shock and multi-organ system failure. So, COVID-19 infection can cause overall worsening of these previous respiratory diseases, such as asthma, chronic obstructive pulmonary disease (COPD), interstitial lung disease, etc. This review aims to provide information on the impact of the COVID-19 disease on pre-existing lung comorbidities
Eficacia de un plan de formaciĂłn en atenciĂłn primaria sobre el sĂndrome de apneas-hipopneas durante el sueño
Soluble PD-L1 is a potential biomarker of cutaneous melanoma aggressiveness and metastasis in obstructive sleep apnoea patients.
Obstructive sleep apnoea (OSA) upregulates the programmed cell death-1 receptor and its ligand (PD-L1) pathway, potentially compromising immunosurveillance. We compared circulating levels of soluble PD-L1 (sPD-L1) in patients with cutaneous melanoma according to the presence and severity of OSA, and evaluated relationships with tumour aggressiveness and invasiveness.In a multicentre observational study, 360 patients with cutaneous melanoma underwent sleep studies, and serum sPD-L1 levels were assayed using ELISA. Cutaneous melanoma aggressiveness indices included mitotic rate, Breslow index, tumour ulceration, Clark level and tumour stage, and sentinel lymph node (SLN) metastasis was recorded as a marker of invasiveness.sPD-L1 levels were higher in severe OSA compared to mild OSA or non-OSA patients. In OSA patients, sPD-L1 levels correlated with Breslow index and were higher in patients with tumour ulceration, advanced primary tumour stages or with locoregional disease. The incorporation of sPD-L1 to the classic risk factors to SLN metastasis led to net improvements in the classification of 27.3%.Thus, sPD-L1 levels are increased in melanoma patients with severe OSA, and, in addition, might serve as a potential biomarker of cutaneous melanoma aggressiveness and invasiveness in this group of subjects