An Assessment of Gelatinous Zooplankton and Impacts on Planktonic Community Structure in Barnegat Bay, New Jersey

Local populations of gelatinous zooplankton are experiencing increases in response to changes in coastal ecosystems due to anthropogenic forces. The abundance of the Atlantic sea nettle (Chrysaora quinquecirrha) has dramatically increased in Barnegat Bay, NJ. Lift net sampling was used to determine the density and distribution of sea nettle and ctenophore {Mnemiopsis leidyi) populations, while zooplankton tows were used to compare relationships between their abundance to that of other zooplankton species. Lift net results showed substantial spatial and temporal variability in density and distribution of ctenophores and sea nettles, with these patterns being inversely proportional. Chrysaora quinquecirrha was more abundant in north Barnegat Bay while Mnemiopsis leidyi was more abundant in the south. Zooplankton tow results showed similar trends on spatial and temporal scales. Chrysaora quinquecirrha was collected in southern sample sites, suggesting the expansion of sea nettles in Barnegat Bay. Correlation analysis for the abundance of Mnemiopsis leidyi against other zooplankton suggests predation upon copepods, fish eggs, larval fish, crab and shrimp larvae and is indicative of potential top-down structuring forces in the pelagic community. Correlation analysis between C. quinquecirrha and M. leidyi suggests predation upon the ctenophore species by the scyphozoan

Impact of Age on the Cerebrovascular Proteomes of Wild-Type and Tg-SwDI Mice

The structural integrity of cerebral vessels is compromised during ageing. Abnormal amyloid (Aβ) deposition in the vasculature can accelerate age-related pathologies. The cerebrovascular response associated with ageing and microvascular Aβ deposition was defined using quantitative label-free shotgun proteomic analysis. Over 650 proteins were quantified in vessel-enriched fractions from the brains of 3 and 9 month-old wild-type (WT) and Tg-SwDI mice. Sixty-five proteins were significantly increased in older WT animals and included several basement membrane proteins (nidogen-1, basement membrane-specific heparan sulfate proteoglycan core protein, laminin subunit gamma-1 precursor and collagen alpha-2(IV) chain preproprotein). Twenty-four proteins were increased and twenty-one decreased in older Tg-SwDI mice. Of these, increases in Apolipoprotein E (APOE) and high temperature requirement serine protease-1 (HTRA1) and decreases in spliceosome and RNA-binding proteins were the most prominent. Only six shared proteins were altered in both 9-month old WT and Tg-SwDI animals. The age-related proteomic response in the cerebrovasculature was distinctly different in the presence of microvascular Aβ deposition. Proteins found differentially expressed within the WT and Tg-SwDI animals give greater insight to the mechanisms behind age-related cerebrovascular dysfunction and pathologies and may provide novel therapeutic targets

Observations of Comets

International audienc

Observations of Comets

International audienc

Observations of Comets

International audienc