Increasing Performances of TCP Data Transfers Through Multiple Parallel Connections

Although Transmission Control Protocol (TCP) is a widely deployed and successful protocol, it shows some limitations in present-day environments. In particular, it is unable to exploit multiple (physical or logical) paths between two hosts. This paper presents PATTHEL, a session-layer solution designed for parallelizing stream data transfers. Parallelization is achieved by striping the data flow among multiple TCP channels. This solution does not require invasive changes to the networking stack and can be implemented entirely in user space. Moreover, it is flexible enough to suit several scenarios - e.g. it can be used to split a data transfer among multiple relays within a peer-to-peer overlay networ

Increasing Performances of TCP Data Transfers Through Multiple Parallel Connections

Although Transmission Control Protocol (TCP) is a widely deployed and successful protocol, it shows some limitations in present-day environments. In particular, it is unable to exploit multiple (physical or logical) paths between two hosts. This paper presents PATTHEL, a session-layer solution designed for parallelizing stream data transfers. Parallelization is achieved by striping the data flow among multiple TCP channels. This solution does not require invasive changes to the networking stack and can be implemented entirely in user space. Moreover, it is flexible enough to suit several scenarios - e.g. it can be used to split a data transfer among multiple relays within a peer-to-peer overlay network

Socio-emotional and cognitive development in intrauterine growth restricted (IUGR) and typical development infants: Early interactive patterns and underlying neural correlates. Rationale and methods of the study

Intrauterine growth restriction (IUGR) is defined as a fetal growth retardation, resulting in an estimated fetal weight less than the 10th centile for gestational age. IUGR developing brain is affected by the atypical fetal growth, presenting altered structure and connectivity and increased risk for neurodevelopmental impairments. Behaviorally, IUGR infants show reduced responsiveness and engagement with human faces during mother-child exchanges. The neural mechanisms of these patterns of interactions remain unexplored, as well as their potential role in shaping socio-cognitive trajectories of development. Aim of this research project will be to longitudinally investigate mother-infant interactions and infant's event-related potential (ERP) components of face processing (infant N170, P400, Negative central) in 4 and 9 months IUGR as potential early markers of expected atypical cognitive and behavioral outcomes observed at 12 months. Thirty IUGR participants will be recruited after receiving the in utero diagnosis (>28th gestational week). Thirty healthy infants will be enrolled as the control group. Maternal environment will be assessed via Emotional Availability Scales (EASs), with child responsiveness and maternal sensitivity as variables of interest. Infants' scalp-recorded cortical activity in response to social and non-social stimuli will be investigated using a high-density EEG system (EGI Geodesic system). Neurodevelopment will be measured at 12 months of child's life, using Bayley Scales for Infant Development (BSID), while the possible presence of emotional-behavioral problems will be rated via Child Behavior Checklist (CBCL). We expect that being IUGR significantly affects cognitive and behavioral outcomes, through mediation effects of both infants' neural and behavioral capacity to respond to social stimuli. Indeed, we expect an altered response to social stimuli in IUGR infants, resulting in smaller ERP components amplitude in response to human faces compared to healthy matched peers. A significant association between neural response to social stimuli and infants' responsiveness to maternal stimulation during interactions is expected, with impoverished performances on the interactive domain in IUGR, compared to healthy peers. This study will enhance understanding on neural mechanisms underpinning the interactive patterns sustaining socio-cognitive development in IUGR and healthy infants. The study will help in clarifying the role of postnatal environment in buffering the vulnerability experienced by children delayed in their fetal growth

The dynamic association between Frailty, CD4 and CD4/CD8 ratio in people aging with HIV

To investigate the association between current CD4+ T-cell count and CD4/CD8+ ratio with severity of frailty among people aging with HIV

Anthropogenic Impact on Beach Heterogeneity within a Littoral Cell (Northern Tuscany, Italy)

In this paper the evolution of the Northern Tuscany littoral cell is documented through a detailed analysis of the increasing anthropogenic pressure since the beginning of the 20th century. This sector of the Tuscany coast has been experiencing strong erosion effects that resulted in the loss of large volumes of sandy beaches. The anthropogenic impact on natural processes have been intensified by the construction of two ports in the early decades of the 20th century. Competent authorities reacted by building hard protection structures that tried to fix the position of the shoreline but offset the erosion drive downdrift. Therefore, in the last 20 years a regional Plan was undertaken to gradually replace the hard defense schemes with a softer approach, which involved a massive use of sediment redistribution activities. Many nourishments have been done ever since, using both sand and gravel. All these hard and soft protection operations have been archived in a geodatabase, and visualized in maps that clearly show the progressive change from hard to soft defense. This database may improve the approach to any future analysis of the littoral cell both in terms of research and management, while providing a practical example that may be easily replicated elsewhere

Altered social attention in anorexia nervosa during real social interaction

The capacity to devote attentional resources in response to body-related signals provided by others is still largely unexplored in individuals with Anorexia Nervosa (AN). Here, we tested this capacity through a novel paradigm that mimics a social interaction with a real partner. Healthy individuals (Experiment 1) and individuals with AN (Experiment 2) completed a task with another person which consisted in performing, alternatively, rapid aiming movements to lateralised targets. Generally, this task leads to a form of Inhibition of Return (IOR), which consists of longer reaction times when an individual has to respond to a location previously searched by either himself (individual IOR) or by the partner (social IOR) as compared to previously unexplored locations. IOR is considered as an important attentional mechanism that promotes an effective exploration of the environment during social interaction. Here, healthy individuals displayed both individual and social IOR that were both reliable and of the same magnitude. Individuals with AN displayed a non-significant individual IOR but a reliable social IOR that was also significantly stronger than individual IOR. These results suggest the presence of a reduced sensitivity in processing body-related stimuli conveyed by oneself in individuals with AN which is reflected in action-based attentional processes

Aging with HIV vs. HIV Seroconversion at Older Age: A Diverse Population with Distinct Comorbidity Profiles

People aging with HIV might have different health conditions compared with people who seroconverted at older ages. The study objective was to assess the prevalence of, and risk factors for, individual co-morbidities and multimorbidity (MM) between HIV-positive patients with a longer duration of HIV infection, and patients who seroconverted at an older age. We compared estimates across both groups to a matched community-based cohort sampled from the general population