516 research outputs found
Acoustic radiation from the end of two-dimensional duct, effects of uniform flow and duct lining
A study is presented of the radiation of acoustic modes from the end of a duct immersed in a uniformly moving medium. It is shown that the uniform flow has roughly the same effect as an increase in frequency at constant mode number: the number of lobes of the radiation pattern increases, and the radiation maximum is slightly displaced towards the duct axis. When the mode is near cut-off the forward radiation for an inlet is enhanced. The acoustic radiation characteristics of ducts with soft or absorbing walls and hard, perfectly-reflecting walls are then compared. It is shown, and this is of technological interest, that the side radiation from the end of an acoustically soft duct is greatly reduced for lower-order modes
Acoustic transmission and reflection by a shear discontinuity separating hot and cold regions
Acoustic transmission and reflection is analyzed for plane waves propagating from a hot moving medium, impinging on a plane shear discontinuity into a cold stationary region. It is shown that incident waves originating in the hot region and propagating in the flow direction are transmitted into the cold region at almost right angles to the interface. The result is employed to examine the strong side radiation of internal noise transmitted through the exhaust duct of a turbojet engine
Preliminary Water Assessment Reports of The Test Basins of The Watch Project
This report presents the initial plans of the case studies how they link to rest of the Watch project and on which water resources they will focus. This report will function as the basis for further discussions on how to improve the integration of the case studies within the project and to develop a more general protocol for each of the case studies. Currently 5 catchments are used within the Watch project, they differ in climatic and hydro-geological features and expected climate changes: the Glomma River basin (Eastern Norway), the upper Guadiana basin (Central Spanish Plateau), the Nitra River basin (central Slovakia), the Upper-Elbe basin (part of the Elbe River) and the island of Crete. Also the water resources issues vary over these cases. Agricultural (and domestic) water use is under pressure in the Mediterranean catchments probably aggravating with the expected increase in drought frequency under future climate. The Norwegian catchment provides hydropower services under threat of precipitation increase rather than decrease. The central European catchments are threatened mainly by increased variability, i.e. increased frequencies of extremes in a densely populated environment, and river flow may need additional buffers (reservoirs) to reduce floodrisk and store water for dry period
A binding event converted into a folding event
AbstractWe have designed a chimeric protein by connecting a circular permutant of the α-spectrin SH3 domain to the proline-rich decapeptide APSYSPPPPP with a three-residue link. Our aim was to obtain a single-chain protein with a tertiary fold that would mimic the binding between SH3 domains and proline-rich peptides. A comparison of the circular-dichroism and fluorescence spectra of the purified chimera and the SH3 circular permutant showed that the proline-rich sequence occupies the putative SH3 binding site in a similar conformation and with comparable interactions to those found in complexes between SH3 and proline-rich peptides. Differential scanning calorimetry indicated that the interactions in the binding motif interface are highly cooperative with the rest of the structure and thus the protein unfolds in a two-state process. The chimera is more stable than the circular permutant SH3 by 6–8 kJ mol−1 at 25°C and the difference in their unfolding enthalpy is approximately 32 kJ mol−1, which coincides with the values found for the binding of proline-rich peptides to SH3 domains. This type of chimeric protein may be useful in designing SH3 peptide ligands with improved affinity and specificity
Black Hole Entropy, Topological Entropy and the Baum-Connes Conjecture in K-Theory
We shall try to exhibit a relation between black hole entropy and topological
entropy using the famous Baum-Connes conjecture for foliated manifolds which
are particular examples of noncommutative spaces. Our argument is qualitative
and it is based on the microscopic origin of the Beckenstein-Hawking
area-entropy formula for black holes, provided by superstring theory, in the
more general noncommutative geometric context of M-Theory following the Connes-
Douglas-Schwarz article.Comment: 17 pages, Latex, contains an important paragraph in section 2 which
gives a better understandin
Polar Smectic Films
We report on a new experimental procedure for forming and studying polar
smectic liquid crystal films. A free standing smectic film is put in contact
with a liquid drop, so that the film has one liquid crystal/liquid interface
and one liquid crystal/air interface. This polar environment results in changes
in the textures observed in the film, including a boojum texture and a
previously unobserved spiral texture in which the winding direction of the
spiral reverses at a finite radius from its center. Some aspects of these
textures are explained by the presence of a Ksb term in the bulk elastic free
energy density that favors a combination of splay and bend deformations.Comment: 4 pages, REVTeX, 3 figures, submitted to PR
Notes on the Third Law of Thermodynamics.I
We analyze some aspects of the third law of thermodynamics. We first review
both the entropic version (N) and the unattainability version (U) and the
relation occurring between them. Then, we heuristically interpret (N) as a
continuity boundary condition for thermodynamics at the boundary T=0 of the
thermodynamic domain. On a rigorous mathematical footing, we discuss the third
law both in Carath\'eodory's approach and in Gibbs' one. Carath\'eodory's
approach is fundamental in order to understand the nature of the surface T=0.
In fact, in this approach, under suitable mathematical conditions, T=0 appears
as a leaf of the foliation of the thermodynamic manifold associated with the
non-singular integrable Pfaffian form . Being a leaf, it cannot
intersect any other leaf const. of the foliation. We show that (N) is
equivalent to the requirement that T=0 is a leaf. In Gibbs' approach, the
peculiar nature of T=0 appears to be less evident because the existence of the
entropy is a postulate; nevertheless, it is still possible to conclude that the
lowest value of the entropy has to belong to the boundary of the convex set
where the function is defined.Comment: 29 pages, 2 figures; RevTex fil
Sex differences in clinical presentation and risk stratification in the emergency department: an observational multicenter cohort study
Objective: The aim of this study was to investigate whether sex differences exist in disease presentations, disease severity and (case-mix adjusted) outcomes in the Emergency Department (ED).Methods: Observational multicenter cohort study using the Netherlands Emergency Department Evaluation Database (NEED), including patients >= 18 years of three Dutch EDs. Multivariable logistic regression was used to study the associations between sex and outcome measures in-hospital mortality and Intensive Care Unit/Medium Care Unit (ICU/MCU) admission in ED patients and in subgroups triage categories and presenting complaints.Results: Of 148,825 patients, 72,554 (48.8%) were females. Patient characteristics at ED presentation and diagnoses (such as pneumonia, cerebral infarction, and fractures) were comparable between sexes at ED presentation. In-hospital mortality was 2.2% in males and 1.7% in females. ICU/MCU admission was 4.7% in males and 3.1% in females. Males had higher unadjusted (OR 1.34(1.25-1.45)) and adjusted (AOR 1.34(1.24-1.46)) risks for mortality, and unadjusted (OR 1.54(1.46-1.63)) and adjusted (AOR 1.46(1.37-1.56)) risks for ICU/MCU admission. Males had higher adjusted mortality and ICU/MCU admission for all triage categories, and with almost all presenting complaints except for headache.Conclusions: Although patient characteristics at ED presentation for both sexes are comparable, males are at higher unadjusted and adjusted risk for adverse outcomes. Males have higher risks in all triage categories and with almost all presenting complaints. Future studies should investigate reasons for higher risk in male ED patients
Secondary LS category of measured laminations
In the author's Ph.D., a version of the tangential LS category for foliated
spaces depending on a transverse invariant measure, called the measured
category, was introduced. Unfortunately, the measured category vanishes easily.
When it is zero, the rate of convergence to zero of the quantity involved in
the definition, by taking arbitrarily large homotopies, gives a new invariant,
called the secondary measured category. Several versions of classical results
are proved for the secondary measured category. It is also shown that the
secondary measured category is a transverse invariant related to the growth of
(pseudo)groups. The equality between secondary category and the growth of a
group is done in the case of free suspensions by Rohlin groups.Comment: 14 pages. arXiv admin note: substantial text overlap with
arXiv:1112.500
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