Subluxación vertebral como complicación a una descompresión ventral-cervical slot

Este trabajo describe un caso clínico de hernia discal cervical Hansen tipo I en un perro de raza Alaska malamute de 4 años de edad que fue resuelta mediante descompresión ventral, creando un slot con el fin de retirar el material extruido. La evolución fue buena pero, a las 5 semanas de la cirugía, se produjo una subluxación y colapso vertebral en el lugar donde se había practicado la descompresión. Se trató la inestabilidad mediante tornillos. de 4 mm de diámetro anclados en los cuerpos vertebrales adyacentes y cemento de metil-metacrilato.A case of Hansen Type I cervical disk herniation in a 4-year-old Alaska malamute is described. Surgical treatment consisted of a ventral decompression through a slot in order to retrieve the extruded material. The follow-up period was uneventful until subluxation and vertebral collapse ocurred at the surgical site 5 weeks postoperatively. The subluxation was stabilized with 4 mm. screws and methylmetacrilate bone cement

Eficacia de la ivermectina oral en el tratamiento de la sarna demodécica canina resistente al almitraz

Se describen dos casos de sarna demodécica canina resistente al amitraz, tratados con ivermectina por vía oral a dosis de 600 mcg/kg durante 3 y 5 meses respectivamente.Two cases of amitraz-resistant generalized demodicosis treated with ivermectin 600 mcg/kg during 3 and 5 months respectiuely

Hepatozoonosis canina.Estudio retrospectivo de 8 casos clínicos

Se describen ocho casos de hepatozonoosis canina diagnosticados en la Clínica Veterinaria Canis mediante identificación del microorganismo en extensiones de sangre y lo médula ósea. Se incluyen el cuadro clínico, pruebas laboratoriales de diagnóstico, pautas de tratamiento y evolución clínica.Hight cases of canine hepatozoonosis diagnosed at Clinica Veterinaria Canis by identzfication of the organism on blood and/or bone marrow smears are descried. Clinical signs, hematologic and biochemistry findings, diferent treatment, protocols and jollow up are included

Cyclic disulfide model of the major antigenic site of serotype-C foot-and-mouth disease virus Synthetic, conformational and immunochemical studies

AbstractA cyclic disulfide peptide representing antigenic site A of foot-and-mouth-disease virus (FMDV) strain C-S8cl (residues 134 to 155 of viral protein l (VP1) with Tyr136 and Arg153 replaced by cystine; TTCTASARGDLAHLTTTHACHL) was synthesized by solid phase methods. Formation of the cyclic disulfide was carried out by air oxidation of the fully deprotected and reduced bis-cysteine precursor, under high dilution conditions. The identity of the cyclic peptide was confirmed by both physical and enzymatic methods. A conformational study of the cyclic peptide and of its linear parent structure (YTASARGDLAHLTTTHARHLP, residues 136–156 of VP1 of FMDV C-S8cl) by circular dichroism in the presence of a structure-inducing solvent showed the cyclic disulfide analog to adopt lower levels of α-helix than its linear counterpart. In competitive ELISA assays both peptides reacted with similar affinity against a representative panel of neutralizing monoclonal antibodies directed towards antigenic site A. Thus, a high inherent flexibility of this loop may preclude a conformational restriction strong enough to alter recognition by anti-virus antibodies

Seroprevalence of canine Leishmania infantum infection in the Mediterranean region and identification of risk factors: The example of North-Eastern and Pyrenean areas of Spain

The Mediterranean basin is an endemic region for canine leishmaniosis (CanL), where it represents a major veterinary problem and raises human health concerns. However, the distribution of the disease is heterogeneous and not all countries and locations have been equally studied and characterized. This work describes the situation of CanL in Girona province (Catalonia, Spain), for which no data has been previously reported, and presents a relevant study to exemplify other areas with similar characteristics across the region. Four cross-sectional seroprevalence surveys were performed from 2012 to 2016 throughout the province, including 36 sampling stations in 26 localities and a total of 593 dogs. For each animal, individual and location variables were also collected. Additionally, each dog owner answered a questionnaire about their knowledge of CanL and preventive methods used. Blood samples were analysed by an in-house ELISA and a mixed logistic regressio nmodel was used to assess the relationship between pre-determined variables and dog seropositivity. A Spearman's correlation was used to assess the association between dog owners'perceived risk of CanL an dLeishmania infantums eropositivity in dogs at a given location. The overall true seroprevalence estimated forGirona province was 19.5% (95%CI: 15.5-23.5), of which only 6.8% (10/146) were considered symptomatic. Age of the dog [OR = 1.21 (95%CI: 1.11-1.31); p < 0.001] and altitude [OR = 0.02 (95%CI: 0.001-0.19);p = 0.001] were identified as risk factors for the infection. The results obtained in this study are expected to aid in the implementation of directed control programmes in CanL endemic areas throughout Europe, as well as to provide suitable data for the design of better risk assessment maps of the diseas

Strategies to reengage patients lost to follow up in HIV care in high income countries, a scoping review

Background: Despite remarkable achievements in antiretroviral therapy (ART), losses to follow-up (LTFU) might prevent the long-term success of HIV treatment and might delay the achievement of the 90-90-90 objectives. This scoping review is aimed at the description and analysis of the strategies used in high-income countries to reengage LTFU in HIV care, their implementation and impact. Methods: A scoping review was done following Arksey & O'Malley's methodological framework and recommendations from Joanna Briggs Institute. Peer reviewed articles were searched for in Pubmed, Scopus and Web of Science; and grey literature was searched for in Google and other sources of information. Documents were charted according to the information presented on LTFU, the reengagement procedures used in HIV units in high-income countries, published during the last 15 years. In addition, bibliographies of chosen articles were reviewed for additional articles. Results: Twenty-eight documents were finally included, over 80% of them published in the United States later than 2015. Database searches, phone calls and/or mail contacts were the most common strategies used to locate and track LTFU, while motivational interviews and strengths-based techniques were used most often during reengagement visits. Outcomes like tracing activities efficacy, rates of reengagement and viral load reduction were reported as outcome measures. Conclusions: This review shows a recent and growing trend in developing and implementing patient reengagement strategies in HIV care. However, most of these strategies have been implemented in the United States and little information is available for other high-income countries. The procedures used to trace and contact LTFU are similar across reviewed studies, but their impact and sustainability are widely different depending on the country studied

Salisbury College Art and design

SIGLEAvailable from British Library Document Supply Centre-DSC:7168.13917(1/2001) / BLDSC - British Library Document Supply CentreGBUnited Kingdo

Ostosarcoma vertebral con invasión de raíces nerviosas y médula espinal en un perro

En este artículo se describe un caso de osteosarcama vertebral que presenta un comportamiento atípica al formar una masa paravertebral e invadir las raíces nerviosas y la médula espinal. Se presenta también una revisión sobre los signos clínicos, diagnóstico, pronóstico y tratamiento de los osteosarcomas vertebrales.A case of vertebral osteosarcoma with a typical behaviour is described. The tumor forms a paravertebral mass and invades the nerve roots and the spinal cord. A review of clinical signs, diagnosis, prognosis and treatment of vertebral osteosarcomas is also presented