A COMPARISON BETWEEN EXPERIMENTAL AND NUMERICAL ANALYSIS OF A WELLS TURBINE

Wave energy is one of the renewable energy sources with the highest potential. Several pilot plants have been built based on the principle of the Oscillating Water Column (OWC). Among the different solutions that have been suggested, the Wells turbine has gained particular attention due to its simplicity and reliability. The majority of available studies concentrate on the steady operation of the Wells turbine, while only few analyze its performance under an unsteady and bi-directional air flow, as determined by the presence of the OWC system. In this work, experimental and numerical performance of a high-solidity Wells turbine with NACA0015 profiles under the bi-directional flow generated by a hydraulic piston is compared. The numerical simulations have been conducted using commercial CFD software and focus on unsteady predictions, with particular attention to the behavior of the flow upstream and down-stream of the rotor, flow hysteresis between acceleration and deceleration phases and differences between intake and exhaust strokes due to the non-symmetrical configuration of the machine

Pumps as turbines for pumped hydro energy storage systems - A small-size case study

Pumped Hydro Energy Storage (PHES) technology has been used since early 1890s and is, nowadays, a consolidated and commercially mature technology. PHES systems allow energy to be stored by pumping water from a lower-to a higher-level reservoir. Subsequently, this energy can be released through a turbine placed in a penstock, which connects the two reservoirs, to produce energy. Although these plants have historically been employed at large power scales (in the order of hundreds of MW), in recent years, micro- and small-scale plants are becoming more interesting, due to their possibility of being integrated with renewable energy systems (RES) used in autonomous island grids. Capital costs associated with hydraulic machines used in PHES systems represent the most critical economic factor, which can be mitigated by using commercial centrifugal pumps in reverse mode (Pumps as Turbines, PATs) in place of small hydro turbines. These expected economic benefits must be weighed in each specific case study, with some drawbacks related to the use of PATs, mainly associated to a lower round-trip efficiency with respect to specifically designed pumps and turbines. In this work, a small-scale PHES plant has been studied coupled to an existent photovoltaic system for the integration in the electric grid of a small island in Southern Italy. Two different PHES outlines have been compared based on techno-economic considerations. The former is a typical PHES system composed of both pumps and a turbine, while the latter uses only an array of parallel pumps which work also in reverse mode. The analysis demonstrates the feasibility of integrating a photovoltaic and PHES plant, which results in a lower cost of electricity production, while PHES performance in the PAT-based outline results penalized by the lower efficiency of PATs with respect to the hydraulic turbine

Perfectly Matched Layer for Linearized Euler Equations in Open and Ducted Domains

Recently, perfectly matched layer (PML) as an absorbing boundary condition has widespread applications. The idea was first introduced by Berenger for electromagnetic waves computations. In this paper, it is shown that the PML equations for the linearized Euler equations support unstable solutions when the mean flow has a component normal to the layer. To suppress such unstable solutions so as to render the PML concept useful for this class of problems, it is proposed that artificial selective damping terms be added to the discretized PML equations. It is demonstrated that with a proper choice of artificial mesh Reynolds number, the PML equations can be made stable. Numerical examples are provided to illustrate that the stabilized PML performs well as an absorbing boundary condition. In a ducted environment, the wave mode are dispersive. It will be shown that the group velocity and phase velocity of these modes can have opposite signs. This results in a confined environment, PML may not be suitable as an absorbing boundary condition

Numerical Evaluation of Entropy Generation in Isolated Airfoils and Wells Turbines

In recent years, a number of authors have studied entropy generation in Wells turbines. This is potentially a very interesting topic, as it can provide important insights into the irreversibilities of the system, as well as a methodology for identifying, and possibly minimizing, the main sources of loss. Unfortunately, the approach used in these studies contains some crude simplifications that lead to a severe underestimation of entropy generation and, more importantly, to misleading conclusions. This paper contains a re-examination of the mechanisms for entropy generation in fluid flow, with a particular emphasis on RANS equations. An appropriate methodology for estimating entropy generation in isolated airfoils and Wells turbines is presented. Results are verified for different flow conditions, and a comparison with theoretical values is presented.Regione Autonoma Sardegna (funding for University of Cagliari co-authors

Correction to: Numerical evaluation of entropy generation in isolated airfoils and Wells turbines

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ETS-related gene (ERG) undermines genome stability in mouse prostate progenitors via Gsk3β dependent Nkx3.1 degradation.

21q22.2-3 deletion is the most common copy number alteration in prostate cancer (PCa). The genomic rearrangement results in the androgen-dependent de novo expression of ETS-related gene (ERG) in prostate cancer cells, a condition promoting tumor progression to advanced stages of the disease. Interestingly, ERG expression characterizes 5-30% of tumor precursor lesions - High Grade Prostatic Intraepithelial Neoplasia (HGPIN) - where its role remains unclear. Here, by combining organoids technology with Click-chemistry coupled Mass Spectrometry, we demonstrate a prominent role of ERG in remodeling the protein secretome of prostate progenitors. Functionally, by lowering autocrine Wnt-4 signaling, ERG represses canonical Wnt pathway in prostate progenitors, and, in turn, promotes the accumulation of DNA double strand breaks via Gsk3β-dependent degradation of the tumor suppressor Nkx3.1. On the other hand, by shaping extracellular paracrine signals, ERG strengthens the pro-oxidative transcriptional signature of inflammatory macrophages, which we demonstrate to infiltrate pre-malignant ERG positive prostate lesions. These findings highlight previously unrecognized functions of ERG in undermining adult prostate progenitor niche through cell autonomous and non-autonomous mechanisms. Overall, by supporting the survival and proliferation of prostate progenitors in the absence of growth stimuli and promoting the accumulation of DNA damage through destabilization of Nkx3.1, ERG could orchestrate the prelude to neoplastic transformation

Mapping and Functional Characterisation of a CTCF-Dependent Insulator Element at the 3′ Border of the Murine Scl Transcriptional Domain

The Scl gene encodes a transcription factor essential for haematopoietic development. Scl transcription is regulated by a panel of cis-elements spread over 55 kb with the most distal 3′ element being located downstream of the neighbouring gene Map17, which is co-regulated with Scl in haematopoietic cells. The Scl/Map17 domain is flanked upstream by the ubiquitously expressed Sil gene and downstream by a cluster of Cyp genes active in liver, but the mechanisms responsible for delineating the domain boundaries remain unclear. Here we report identification of a DNaseI hypersensitive site at the 3′ end of the Scl/Map17 domain and 45 kb downstream of the Scl transcription start site. This element is located at the boundary of active and inactive chromatin, does not function as a classical tissue-specific enhancer, binds CTCF and is both necessary and sufficient for insulator function in haematopoietic cells in vitro. Moreover, in a transgenic reporter assay, tissue-specific expression of the Scl promoter in brain was increased by incorporation of 350 bp flanking fragments from the +45 element. Our data suggests that the +45 region functions as a boundary element that separates the Scl/Map17 and Cyp transcriptional domains, and raise the possibility that this element may be useful for improving tissue-specific expression of transgenic constructs

Impiego di un metodo numerico ad alta accuratezza per lo studio di problemi di aeroacustica

Dottorato di ricerca in progettazione meccanica. 10. cicloConsiglio Nazionale delle Ricerche - Biblioteca Centrale - P.le Aldo Moro, 7, Rome; Biblioteca Nazionale Centrale - P.za Cavalleggeri, 1, Florence / CNR - Consiglio Nazionale delle RichercheSIGLEITItal