An Interpretative Phenomenological Study Exploring the Experiences of African American Males in Same Race/Gender Mentoring Relationships While Attending a Predominately White Institution in the South

This exploratory study was undertaken to assess the experiences of undergraduate (and recent graduate) African American male students who were currently involved in a mentoring relationship with another African American male, while attending a Predominantly White Institution in the South. The researcher used purposive sampling to select undergraduate participants who had formed mentoring relationships with other African American males. Face-to-face interviews were conducted and the interview transcripts were analyzed for structural elements or master themes, using interpretive phenomenological analysis (IPA) as a guide. The findings suggest that these relationships played a role in helping undergraduate African American males navigate college life successfully while attending a Predominately White Institution in the South

Final evaluation of the saving gateway 2 pilot: main report

The Saving Gateway is a government initiative aimed at encouraging savings behaviour among people who do not usually save. Each pound placed into a Saving Gateway account is matched by the government at a certain rate and up to a monthly contribution limit. Matching provides a transparent and understandable incentive for eligible individuals to place funds in an account

Kainic acid-induced eye enlargement in chickens: differential effects on anterior and posterior segments

Intravitreal injections of kainic acid were used to examine the significance of normal retinal activity for eye growth in chickens, this acid being chosen because of its known, selective neurotoxic effects on cells in the chicken retina. A 6 nmole dose of kainic significantly reduces amacrine cell numbers when used in very young chickens, while higher doses of kainic acid also affect bipolar and horizontal cell numbers. The effects of intravitreal injection of kainic acid on eye growth were assessed 4 weeks after treatment. A 200 nmole dose of kainic acid, used with day-old and 14-day-old chickens, had opposing effects on the anterior and posterior segments of the eye; while growth of the anterior segment was inhibited, the posterior segment was enlarged, predominantly in the equatorial direction. A 20 nmole dose of this acid similarly affected growth in 14-day-old chickens, but in day-old chickens, the anterior segment was also enlarged and the overall eye enlargement had an axial bias. Myopia was the most common refractive error associated with both patterns of development. A 2 nmole dose of kainic acid was without effect on eye growth. Parallels are drawn between these eye enlargement phenomena and those described in chickens whose visual environments have been manipulated. Our results indicate that normal retinal activity is fundamental to normal eye growth in chickens, and furthermore, that growth of the anterior and posterior segments of the chicken eye are independently regulated

BCG Cell Imaging Using Scanning Probe Microscopy

Scanning tunneling microscopy (STM) and atomic force microscopy (AFM) were used to obtain images of the surface of whole, intact BCG (bacille Calmette Guerin, a mycobacterium) cells in air and under solution by immobilizing the cells onto glass slides (AFM only) or highly oriented pyrolytic graphite. The technique used for AFM imaging involved depositing a submonolayer of cells under a centrifugal force followed by fixation/dehydration using polar organic solvents. AFM images agree well with images from light and electron microscopy and showed large numbers of BCG cells in their distinctive cord arrangement. The AFM also proved useful for identifying extracellular microgranules which cannot be seen with light microscopy. For STM imaging, the hydrophobicity of BCG enabled strong adhesion from aqueous solution onto graphite. STM images of BCG could only be obtained while scanning in aqueous solution, and the cells showed a large variation in contrast when different samples were imaged. The STM provided greater detail of surface features than the AFM and was able to produce images of periodic layers corroborating observations made by transmission electron microscopy

Failing to Engage: Parents’ Acceptance of the Promotion of Unhealthy Foods to Children

Six focus groups were conducted with parents and children to explore issues relating to the promotion of unhealthy foods to children. While general discontent with food advertising was expressed by parents and children, none of the parents reported ever making a formal complaint and most exhibited a begrudging acceptance of the current rates of advertising of unhealthy foods and the manner in which these foods are promoted. The primary reasons for this acceptance were found to be (i) an understanding that businesses need to promote their products to ensure their survival, (ii) an assumption that parents should be capable of overcoming the negative effects of advertising, (iii) the perceived value of competitions, toys, and other give-aways, and (iv) the increasing availability of healthy product variations

Evaluation of a workplace health and wellbeing training course delivered online and face-to-face

Organisations may benefit from training champions to promote healthy workplace environments and initiatives. This study compared the perceived usefulness and relative effectiveness of an employee training course offered via online and face-to-face formats. Individuals who took part in the training course were assessed on their perceived competence and confidence to implement changes pre-and post-training. Repeated measures Analysis of Variance (ANOVA) and a t-test were conducted to test for significant differences between pre-and post-training scores and/or mode of training, respectively. Although the face-to-face training course was rated as slightly more useful, there were no significant differences between the two modes of training for the other dependent variables, and both modes led to significantly greater perceived competence and confidence post-training. These findings demonstrate the potential benefits of training employees to implement changes in their workplaces

Objective understanding of front-of-package nutrition labels: An international comparative experimental study across 12 countries

Front-of-Package labels (FoPLs) are efficient tools for increasing consumers’ awareness of foods’ nutritional quality and encouraging healthier choices. A label’s design is likely to influence its effectiveness; however, few studies have compared the ability of different FoPLs to facilitate a consumer understanding of foods’ nutritional quality, especially across sociocultural contexts. This study aimed to assess consumers’ ability to understand five FoPLs [Health Star Rating system (HSR), Multiple Traffic Lights (MTL), Nutri-Score, Reference Intakes (RIs), and Warning symbol] in 12 different countries. In 2018, approximately 1000 participants per country were recruited and asked to rank three sets of label-free products (one set of three pizzas, one set of three cakes, and one set of three breakfast cereals) according to their nutritional quality, via an online survey. Participants were subsequently randomised to one of five FoPL conditions and were again asked to rank the same sets of products, this time with a FoPL displayed on pack. Changes in a participants’ ability to correctly rank products across the two tasks were assessed by FoPL using ordinal logistic regression. In all 12 countries and for all three food categories, the Nutri-Score performed best, followed by the MTL, HSR, Warning symbol, and RIs

Alzheimer\u27s disease genetic risk and cognitive reserve in relationship to long-term cognitive trajectories among cognitively normal individuals

BACKGROUND: Both Alzheimer\u27s disease (AD) genetic risk factors and indices of cognitive reserve (CR) influence risk of cognitive decline, but it remains unclear whether they interact. This study examined whether a CR index score modifies the relationship between AD genetic risk factors and long-term cognitive trajectories in a large sample of individuals with normal cognition. METHODS: Analyses used data from the Preclinical AD Consortium, including harmonized data from 5 longitudinal cohort studies. Participants were cognitively normal at baseline (M baseline age = 64 years, 59% female) and underwent 10 years of follow-up, on average. AD genetic risk was measured by (i) apolipoprotein-E (APOE) genetic status (APOE-ε2 and APOE-ε4 vs. APOE-ε3; N = 1819) and (ii) AD polygenic risk scores (AD-PRS; N = 1175). A CR index was calculated by combining years of education and literacy scores. Longitudinal cognitive performance was measured by harmonized factor scores for global cognition, episodic memory, and executive function. RESULTS: In mixed-effects models, higher CR index scores were associated with better baseline cognitive performance for all cognitive outcomes. APOE-ε4 genotype and AD-PRS that included the APOE region (AD-PRS CONCLUSIONS: These results suggest that APOE-ε4 and non-APOE-ε4 AD polygenic risk are independently associated with global cognitive and executive function declines among individuals with normal cognition at baseline, but only APOE-ε4 is associated with declines in episodic memory. Importantly, higher levels of CR may mitigate APOE-ε4-related declines in some cognitive domains. Future research is needed to address study limitations, including generalizability due to cohort demographic characteristics