9,815 research outputs found
Spectral properties of incommensurate charge-density wave systems
The concept of frustrated phase separation is applied to investigate its
consequences for the electronic structure of the high T_c cuprates. The
resulting incommensurate charge density wave (CDW) scattering is most effective
in creating local gaps in k-space when the scattering vector connects states
with equal energy. Starting from an open Fermi surface we find that the
resulting CDW is oriented along the (10)- and (or) (01)-direction which allows
for a purely one-dimensional or a two-dimensional ``eggbox type'' charge
modulation. In both cases the van Hove singularities are substantially
enhanced, and the spectral weight of Fermi surface states near the M-points,
tends to be suppressed. Remarkably, a leading edge gap arises near these
points, which, in the eggbox case, leaves finite arcs of the Fermi surface
gapless. We discuss our results with repect to possible consequences for
photoemission experiments
Role of EGFR in the Nervous System
Epidermal growth factor receptor (EGFR) is the first discovered member of the receptor tyrosine kinase superfamily and plays a fundamental role during embryogenesis and in adult tissues, being involved in growth, differentiation, maintenance and repair of various tissues and organs. The role of EGFR in the regulation of tissue development and homeostasis has been thoroughly investigated and it has also been demonstrated that EGFR is a driver of tumorigenesis. In the nervous system, other growth factors, and thus other receptors, are important for growth, differentiation and repair of the tissue, namely neurotrophins and neurotrophins receptors. For this reason, for a long time, the role of EGFR in the nervous system has been underestimated and poorly investigated. However, EGFR is expressed both in the central and peripheral nervous systems and it has been demonstrated to have specific important neurotrophic functions, in particular in the central nervous system. This review discusses the role of EGFR in regulating differentiation and functions of neurons and neuroglia. Furthermore, its involvement in regeneration after injury and in the onset of neurodegenerative diseases is examined
On the (nonmonotonic) relation between economic growth and finance
We analyze the simplest possible model of endogenous growth to account for the role of financial development. In our setting, financial development affects productivity and determines the amount of resources subtracted to capital investment. We show that under very general assumptions, the relation between economic growth and financial depth is nonmonotonic, and eventually bell-shaped. We empirically assess our results in a framework that allows to distinguish between long-run and short-run effects. We establish a cointegrating relation and derive the long-run elasticities of per capita gross domestic product (GDP) with respect to employment, the physical capital stock, and financial depth\u2014relying on linear as well as nonlinear models for the finance-growth nexus. We employ the results of the first step estimation to specify an error\u2013correction model and find that there is strong evidence for a nonlinear relationship between financial depth and per capita GDP, consistently with what was predicted by our theoretical model
Role of prucalopride in treatment of chronic constipation and recurrent functional obstructionina patient with steinert myotonic dystrophy
Monte Carlo evaluation of the external gamma, neutron and muon induced background sources in the CUORE experiment
CUORE is a 1 ton scale cryogenic experiment aiming at the measurement of the
Majorana mass of the electron neutrino. The detector is an array of 988 TeO2
bolometers used for a calorimetric detection of the two electrons emitted in
the BB0n of 130Te. The sensitivity of the experiment to the lowest Majorana
mass is determined by the rate of background events that can mimic a BB0n. In
this paper we investigate the contribution of external sources i.e.
environmental gammas, neutrons and cosmic ray muons to the CUORE background and
show that the shielding setup designed for CUORE guarantees a reduction of this
external background down to a level <1.0E-02 c/keV/kg/y at the Q-value, as
required by the physical goal of the experiment.Comment: 14 pages, 7 figure
Different approaches for assessing sperm function
Different approaches can be used to assess sperm function in different conditions, i.e. sperm storage, freezing-thawing or activation by induction of capacitation and acrosome reaction. In this review we will focus on the assays routinely performed in our laboratories, giving a literature support to critically analyse different approaches. In fact, researchers usually tend to look for the \u201cone shot\u201c parameter that could explain itself a specific process; it is our conviction that a multiparametric approach is still more valid, as some changes in sperm function are very complex and could be explained only by operating in different ways. Sperm motility, the most evident sperm characteristic, should be assessed by computer-aided sperm analysers that permit an objective evaluation of the motility and its kinematic parameters. Commercial and open source instruments are available and could be profitably used together with specific statistical approaches. The use of microscopy, and particularly fluorescent microscopy, could be a very useful tool to assess different parameters in sperm cells both by fluorophores that give indication of a determined function, and by immunolocalization of proteins, that permits the discover of new features or to explain particular sperm functions. The same substrates could be used also in flow cytometry: the difference is that it permits to study wider sperm populations (and their sub-population distribution). Flow cytometry is undergoing a very wide use in spermatology and technical and experimental rigor is needed to obtain reliable results. Metabolic assessment of sperm features, particularly energetic supply, ATP formation and other enzyme activities, could represent a very important challenge to acquire new information and complete/integrate those derived from other techniques. Finally, functional assays such as oocyte binding and in vitro fertilization, represent a very strong tool to assess sperm function in vitro, as they could evidence the functional intactness of some pathways
Complete elimination of 1K Pot vibrations in dilution refrigerators
Cryogenic vibrations generated by continuously filled 1K Pots are a well known source of noise in all cryogenic experiments using dilution refrigerators. Starting from recent developments we realized a non invasive modification to the cryostat that completely eliminated vibrations, thermalizing the helium coming from the main bath at the pot temperature. We describe the new experimental setup and complete study of the phenomena
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