1,358 research outputs found

    Arthroscopic management of an intraarticular osteochondroma of the hip.

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    The role of hip arthroscopy in the management of femoroacetabular impingement (FAI) has been advancing rapidly. In this case report, we describe the use of hip arthroscopy to successfully treat a femoral neck osteochondroma that caused a symptomatic labral tear in a 37 year old woman. Hip arthroscopy offers several advantages to surgical dislocation of the hip in the management of intraarticular pathology and FAI. Hip arthroscopy is minimally invasive without the significant trauma to hip musculature, is useful in treatment of labral tears generated by FAI, and can be used to resect small lesions on the femoral head

    Testing Asymmetric-Information Asset Pricing Models

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    Theoretical asset pricing models routinely assume that investors have heterogeneous information. We provide direct evidence of the importance of information asymmetry for asset prices and investor demands using plausibly exogenous variation in the supply of information caused by the closure of 43 brokerage firms' research operations in the U.S. Consistent with predictions derived from a Grossman and Stiglitz-type model, share prices and uninformed investors' demands fall as information asymmetry increases. Cross-sectional tests support the comparative statics: Prices and uninformed demand experience larger declines, the more investors are uninformed, the larger and more variable is stock turnover, the more uncertain is the asset's payoff, and the noisier is the better-informed investors' signal. We show that at least part of the fall in prices is due to expected returns becoming more sensitive to liquidity risk. Our results imply that information asymmetry has a substantial effect on asset prices and that a primary channel linking asymmetry to prices is liquidity

    Too-Systemic-To-Fail: What Option Markets Imply About Sector-Wide Government Guarantees

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    A conspicuous amount of aggregate tail risk is missing from the price of financial sector crash insurance during the 2007-2009 crisis. The difference in costs of out-of-the-money put options for individual banks, and puts on the financial sector index, increases fourfold from its pre-crisis level. At the same time, correlations among bank stocks surge, suggesting the high put spread cannot be attributed to a relative increase in idiosyncratic risk. We show that this phenomenon is unique to the financial sector, that it cannot be explained by observed risk dynamics (volatilities and correlations), and that illiquidity and no-arbitrage violations are unlikely culprits. Instead, we provide evidence that a collective government guarantee for the financial sector lowers index put prices far more than those of individual banks, explaining the divergence in the basket-index spread. By embedding a bailout in the standard one-factor option pricing model, we can closely replicate observed put spread dynamics. During the crisis, the spread responds acutely to government intervention announcements

    Quantifying the 2.5D imaging performance of digital holographic systems

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    Digital holographic systems are a class of two step, opto-numerical, three-dimensional imaging techniques. The role of the digital camera in limiting the resolution and field of view of the reconstructed image, and the interaction of these limits with a general optical system is poorly understood. The linear canonical transform describes any optical system consisting of lenses and/or free space in a unified manner. Expressions derived using it are parametrised in terms of the parameters of the optical system, as well as those of the digital camera: aperture size, pixel size and pixel pitch. We develop rules of thumb for selecting an optical system to minimise mean squared error for given input and digital camera parameters. In the limit, our results constitute a point spread function analysis. The results presented in this paper will allow digital holography practitioners to select an optical system to maximise the quality of their reconstructed image using a priori knowledge of the camera and object

    Medication adherence in patients with myotonic dystrophy and facioscapulohumeral muscular dystrophy

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    Myotonic dystrophy (DM) and facioscapulohumeral muscular dystrophy (FSHD) are the two most common adult muscular dystrophies and have progressive and often disabling manifestations. Higher levels of medication adherence lead to better health outcomes, especially important to patients with DM and FSHD because of their multisystem manifestations and complexity of care. However, medication adherence has not previously been studied in a large cohort of DM type 1 (DM1), DM type 2 (DM2), and FSHD patients. The purpose of our study was to survey medication adherence and disease manifestations in patients enrolled in the NIH-supported National DM and FSHD Registry. The study was completed by 110 DM1, 49 DM2, and 193 FSHD patients. Notable comorbidities were hypertension in FSHD (44 %) and DM2 (37 %), gastroesophageal reflux disease in DM1 (24 %) and DM2 (31 %) and arrhythmias (29 %) and thyroid disease (20 %) in DM1. Each group reported high levels of adherence based on regimen complexity, medication costs, health literacy, side effect profile, and their beliefs about treatment. Only dysphagia in DM1 was reported to significantly impact medication adherence. Approximately 35 % of study patients reported polypharmacy (taking 6 or more medications). Of the patients with polypharmacy, the DM1 cohort was significantly younger (mean 55.0 years) compared to DM2 (59.0 years) and FSHD (63.2 years), and had shorter disease duration (mean 26 years) compared to FSHD (26.8 years) and DM2 (34.8 years). Future research is needed to assess techniques to ease pill swallowing in DM1 and to monitor polypharmacy and potential drug interactions in DM and FSHD

    Resolution limits in practical digital holographic systems

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    We examine some fundamental theoretical limits on the ability of practical digital holography DH systems to resolve detail in an image. Unlike conventional diffraction-limited imaging systems, where a projected image of the limiting aperture is used to define the system performance, there are at least three major effects that determine the performance of a DH system: i The spacing between adjacent pixels on the CCD, ii an averaging effect introduced by the finite size of these pixels, and iii the finite extent of the camera face itself. Using a theoretical model, we define a single expression that accounts for all these physical effects. With this model, we explore several different DH recording techniques: off-axis and inline, considering both the dc terms, as well as the real and twin images that are features of the holographic recording process. Our analysis shows that the imaging operation is shift variant and we demonstrate this using a simple example. We examine how our theoretical model can be used to optimize CCD design for lensless DH capture. We present a series of experimental results to confirm the validity of our theoretical model, demonstrating recovery of super- Nyquist frequencies for the first time

    Resolution limits in practical digital holographic systems

    Get PDF
    We examine some fundamental theoretical limits on the ability of practical digital holography DH systems to resolve detail in an image. Unlike conventional diffraction-limited imaging systems, where a projected image of the limiting aperture is used to define the system performance, there are at least three major effects that determine the performance of a DH system: i The spacing between adjacent pixels on the CCD, ii an averaging effect introduced by the finite size of these pixels, and iii the finite extent of the camera face itself. Using a theoretical model, we define a single expression that accounts for all these physical effects. With this model, we explore several different DH recording techniques: off-axis and inline, considering both the dc terms, as well as the real and twin images that are features of the holographic recording process. Our analysis shows that the imaging operation is shift variant and we demonstrate this using a simple example. We examine how our theoretical model can be used to optimize CCD design for lensless DH capture. We present a series of experimental results to confirm the validity of our theoretical model, demonstrating recovery of super- Nyquist frequencies for the first time

    Case Report: Ischial Stress Fracture Non-Union in a College Football Player

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    Stress fractures are common injuries associated with repetitive high-impact activities, often in high-level athletes and military recruits. Although predominantly occurring in the lower extremities, stress fractures may occur wherever there is a sudden increase in frequency or intensity of activity, thereby overloading the yield point of the local bone environment. Ischial stress fractures are a rarely diagnosed cause of pain around the hip and pelvis. Often, patients present with buttock pain with activity, which can be misdiagnosed as proximal hamstring tendonitis or avulsion. Here, we report a case of a college football player who was diagnosed with an ischial stress fracture which went on to symptomatic non-union after extensive conservative management. We treated his ischial non-union with open reduction internal fixation utilizing a tension band plate and screws. This interesting case highlights an uncommon cause of the relatively common presentation of posterior hip pain and describes our technique for addressing a stress fracture non-union in the ischium

    Too-Systemic-To-Fail: What Option Markets Imply About Sector-Wide Government Guarantees

    Get PDF
    A conspicuous amount of aggregate tail risk is missing from the price of financial sector crash insurance during the 2007-2009 crisis. The difference in costs of out-of-the-money put options for individual banks, and puts on the financial sector index, increases fourfold from its pre-crisis level. At the same time, correlations among bank stocks surge, suggesting the high put spread cannot be attributed to a relative increase in idiosyncratic risk. We show that this phenomenon is unique to the financial sector, that it cannot be explained by observed risk dynamics (volatilities and correlations), and that illiquidity and no-arbitrage violations are unlikely culprits. Instead, we provide evidence that a collective government guarantee for the financial sector lowers index put prices far more than those of individual banks, explaining the divergence in the basket-index spread. By embedding a bailout in the standard one-factor option pricing model, we can closely replicate observed put spread dynamics. During the crisis, the spread responds acutely to government intervention announcements
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