Analyzing the Effect of Nutrition Education on Snack Food Vending Choices of College Students

Over the last three decades, the U.S. has seen a steady rise in obesity. A commonly proposed solution to combating obesity is to provide nutrition education about healthy eating. While research in this area is on the rise, little to no research on education coupled with a policy that supports healthy snacking has been done on college students, many of whom are making basic snacking and meal decisions for themselves for the first time in their lives. In this study, a pretest/posttest control group design was used to evaluate the impact of nutrition education on snack food choices in college students. Undergraduates enrolled in an introductory human nutrition class were the treatment group (n=71), and undergraduates enrolled in an introductory marketing course were the control group (n=76). Students in both groups were shown a photo of an actual vending machine and were then asked to select an item from the photo that they would choose given five different scenarios (meal replacement, meal supplement, craving, energy, and snack). Logistic regression models were used to evaluate changes in snack food selections between the treatment and control groups. Results demonstrate that students in the treatment group choose significantly healthier snack food choices for scenario 3 (craving, p=.0422) and scenario 4 (energy, p=.0013). From these results, we concluded that nutrition education may impact student snack choices in some situations.No embarg

Shear thickening in densely packed suspensions of spheres and rods confined to few layers

We investigate confined shear thickening suspensions for which the sample thickness is comparable to the particle dimensions. Rheometry measurements are presented for densely packed suspensions of spheres and rods with aspect ratios 6 and 9. By varying the suspension thickness in the direction of the shear gradient at constant shear rate, we find pronounced oscillations in the stress. These oscillations become stronger as the gap size is decreased, and the stress is minimized when the sample thickness becomes commensurate with an integer number of particle layers. Despite this confinement-induced effect, viscosity curves show shear thickening that retains bulk behavior down to samples as thin as two particle diameters for spheres, below which the suspension is jammed. Rods exhibit similar behavior commensurate with the particle width, but they show additional effects when the thickness is reduced below about a particle length as they are forced to align; the stress increases for decreasing gap size at fixed shear rate while the shear thickening regime gradually transitions to a Newtonian scaling regime. This weakening of shear thickening as an ordered configuration is approached contrasts with the strengthening of shear thickening when the packing fraction is increased in the disordered bulk limit, despite the fact that both types of confinement eventually lead to jamming.Comment: 21 pages, 14 figures. submitted to the Journal of Rheolog

Delayed cystogenesis and increased ciliogenesis associated with the re-expression of polaris in Tg737 mutant mice

Delayed cystogenesis and increased ciliogenesis associated with the re-expression of polaris inTg737 mutant mice.BackgroundRenal cysts and shortened cilia on renal tubular epithelia have been observed in Tg737orpk (orpk) mutant mice, suggesting a potential connection between cystogenesis and ciliogenesis. To further test this hypothesis we have characterized the progression of cystic disease and cilia expression in orpk, orpk;Tg737Rsq (orpk rescue), and Tg737Δ2-3βGal;Tg737Rsq (KO rescue) mice.MethodsOrpk, orpk rescue, and KO rescue animals were generated and analyzed from postnatal day (P) 0 to P21 (orpk mutants) or from P0 to P210 (orpk rescue and KO rescue animals). Proximal tubules (PT) and collecting tubules (CT) were identified by immunohistochemistry using segment-specific lectins and a segment-specific cystic index was calculated. Scanning electron microscopy was utilized to observe and measure cilia expression in cysts from orpk, orpk rescue, and KO rescue animals.ResultsKO rescue and orpk rescue animals develop adult-onset autosomal-recessive polycystic kidney disease (ARPKD). Ultrastructural analysis of cilia expression revealed that cysts from orpk expressed short cilia, whereas cysts from KO rescue animals expressed normal length cilia and cysts from orpk rescue animals expressed cilia that are two to five times longer than wild type.ConclusionWhile this data is consistent with a role for polaris in ciliogenesis, it does not support a direct connection between ciliogenesis and cystic disease. Similarities in cyst formation and striking differences in cilia expression associated with these ARPKD mouse models indicates that cyst formation and cilia expression are independent phenotypic features regulated by polaris

Effect of Experience Facilitating Problem-Based Learning (PBL) on Physician Assistant Student Outcomes

Abstract Purpose: The impact of prior problem-based learning (PBL) facilitation experience (measured by length of time facilitating) on student learning and student outcomes is unclear. The purpose of this study was to evaluate relationships of facilitator experience in problem-based learning on student outcomes. This study utilized both modified essay questions (MEQ) in the form of patient management assessments and multiple choice question (MCQ) assessments to evaluate different aspects of student acquisition and application of knowledge. Method: This study examined scores from six multiple choice question examinations and six patient management assessments (PMA), one each from six 5-week units arranged by organ system administered to five cohorts of first-year physician assistant students in a hybrid problem-based learning program where 18 of 45 didactic credits are solely problem-based learning. Facilitation experience, measured in total number of prior units facilitated, was calculated for each facilitator and compared with student evaluative measures. Results: Pearson product moment correlations comparing facilitator experience and scores on the patient management assessments and multiple choice question tests showed no statistically significant correlations between facilitator experience and student outcomes. Univariate analysis of variance tests comparing whether faculty were full-time versus adjunct status and status as graduates of a problem-based learning program versus graduates of programs with other pedagogies with student outcomes showed no statistically significant differences. Conclusions: Neither experience of the facilitator, nor status as full-time versus adjunct, nor status as graduate of a problem-based learning program versus other pedagogy was related to student outcomes. Each facilitator in the study participated in training, observation, and weekly meetings, which may outweigh the effects of facilitator experience. Other factors in need of exploration related to student outcomes in future studies include individual intellectual ability, emotional stability, motivation, self-efficacy, and perseverance

Translation inhibition by rocaglates activates a species-specific cell death program in the emerging fungal pathogen Candida auris

Fungal infections are a major contributor to infectious disease-related deaths worldwide. Recently, global emergence of the fungal pathogen Candida auris has caused considerable concern because most C. auris isolates are resistant to fluconazole, the most commonly administered antifungal, and some isolates are resistant to drugs from all three major antifungal classes. To identify novel agents with bioactivity against C. auris, we screened 2,454 compounds from a diversity-oriented synthesis collection. Of the five hits identified, most shared a common rocaglate core structure and displayed fungicidal activity against C. auris These rocaglate hits inhibited translation in C. auris but not in its pathogenic relative Candida albicans Species specificity was contingent on variation at a single amino acid residue in Tif1, a fungal member of the eukaryotic initiation factor 4A (eIF4A) family of translation initiation factors known to be targeted by rocaglates. Rocaglate-mediated inhibition of translation in C. auris activated a cell death program characterized by loss of mitochondrial membrane potential, increased caspase-like activity, and disrupted vacuolar homeostasis. In a rocaglate-sensitized C. albicans mutant engineered to express translation initiation factor 1 (Tif1) with the variant amino acid that we had identified in C. auris, translation was inhibited but no programmed cell death phenotypes were observed. This surprising finding suggests divergence between these related fungal pathogens in their pathways of cellular responses to translation inhibition. From a therapeutic perspective, the chemical biology that we have uncovered reveals species-specific vulnerability in C. auris and identifies a promising target for development of new, mechanistically distinct antifungals in the battle against this emerging pathogen. IMPORTANCE Emergence of the fungal pathogen Candida auris has ignited intrigue and alarm within the medical community and the public at large. This pathogen is unusually resistant to antifungals, threatening to overwhelm current management options. By screening a library of structurally diverse molecules, we found that C. auris is surprisingly sensitive to translation inhibition by a class of compounds known as rocaglates (also known as flavaglines). Despite the high level of conservation across fungi in their protein synthesis machinery, these compounds inhibited translation initiation and activated a cell death program in C. auris but not in its relative Candida albicans Our findings highlight a surprising divergence across the cell death programs operating in Candida species and underscore the need to understand the specific biology of a pathogen in attempting to develop more-effective treatments against it.Published versio

The use of complementary and alternative medicine among california adults with and without cancer.

This article examines the extent and correlates of complementary and alternative medicine (CAM) use among a population-based sample of California adults that is highly diverse in terms of sociodemographic characteristics and health status. As a follow-up to a state-wide health survey of 55,428 people, 9187 respondents were interviewed by phone regarding their use of 11 different types of CAM providers, special diets, dietary supplements, mind-body interventions, self-prayer and support groups. The sample included all participants in the initial survey who reported a diagnosis of cancer, all the non-white respondents, as well as a random sample of all the white respondents. The relation of CAM use to the respondents' demographic characteristics and health status is assessed. CAM use among Californians is generally high, and the demographic factors associated with high rates of CAM use are the same in California as have been found in other studies. Those reporting a diagnosis of cancer and those who report other chronic health problems indicate a similar level of visits to CAM providers. However, those with cancer are less likely to report using special diets, and more likely to report using support groups and prayer. Health status, gender, ethnicity and education have an independent impact upon CAM use among those who are healthy as well as those who report suffering from chronic health problems, although the precise relation varies by the type of CAM used

Visual literacy for libraries: A practical, standards-based guide

When we step back and think about how to situate visual literacy into a library context, the word critical keeps coming up: critical thinking, critical viewing, critical using, critical making, and the list goes on. To understand our approach, start with your own practice, add images, and see where it takes you. Do you encourage students to think critically as they research? How can you extend this experience to images? Do you embrace critical information literacy? Can you bring visual content to enrich that experience? Do you teach students to critically evaluate sources? How can you expand that practice to images? You’ll see a lot of questions in this book, because our approach is inquiry- driven. This is not to say that we don’t cover the basics of image content. Curious about color? Covered. Not sure where to find great images? We’ll show you. Wondering what makes a good presentation? We talk about that too. But what we really want you to get out of this book is a new understanding of how images fit into our critical (there it is again) practice as librarians and how we can advance student learning with our own visual literacy. This book grounds visual literacy in your everyday practice—connecting it to what you know and do as a librarian who engages in reflective practice. Heidi Jacobs put it well when she argued that, for information literacy pedagogy, “one of the best ways for us to encourage students to be engaged learners is for us to become engaged learners, delve deeply into our own problem posing, and embody the kind of engagement we want to see in our students” (Jacobs 2008). We extend this viewpoint to visual literacy pedagogy and provide many opportunities for you to embody the kind of visual literacy that you want to develop in your learners

It Starts at Home: Infusing Radical Empathy into Graduate Education

This interview features a conversation between a library and information science educator (Cooke) and three archival and special collections professionals with varying levels of experience in the field (Warren, Brown, and Jackson). Among the goals of this frank conversation is to highlight the lived experiences of practicing archivists and educators and discuss why it’s becoming increasingly important to talk about empathy, diversity, equity, and inclusion in greater context. As part of that context, we must discuss the need to continuously infuse these values into graduate education, professional development, research, writing, and peer mentoring. Espousing and implementing an ethics of care is an ongoing and necessary process and commitment - to ourselves, to the professions, and to our communities.  Pre-print first published online 10/04/202