3,194 research outputs found
A feasibility study: California Department of Forestry and Fire Protection utilization of infrared technologies for wildland fire suppression and management
NASA's JPL has completed a feasibility study using infrared technologies for wildland fire suppression and management. The study surveyed user needs, examined available technologies, matched the user needs with technologies, and defined an integrated infrared wildland fire mapping concept system configuration. System component trade-offs were presented for evaluation in the concept system configuration. The economic benefits of using infrared technologies in fire suppression and management were examined. Follow-on concept system configuration development and implementation were proposed
Comparison of northern flying and red squirrel phylogenies with focus on the insular United States
Northern flying squirrel (Glaucomys sabrinus) and red squirrel (Tamiasciurus hudsonicus) populations are endemic to northern North America, including the Black Hills. The Black Hills populations are considered disjunct from other populations within their range. We examined insular populations to determine whether arboreal squirrels in the Black Hills each represent a unique population. We trapped and collected ear samples from northern flying and red squirrels in the Black Hills and in areas of Montana, Wyoming, Idaho, Utah, Minnesota, and Wisconsin to infer population phylogenies with special consideration of the Black Hills population. Microsatellite loci and two mtDNA sequences were used for phylogenetic data analyses, including neighbor-joining and maximum likelihood trees, percent divergence, and nucleotide diversity. For northern flying squirrels,mtDNA phylogenetic trees grouped individuals in the Black Hills population, suggesting extended isolation from other nearby mountain ranges. In both squirrels, phylogenetic trees inferred with nDNA provide similar topologies to the mtDNA of northern flying squirrels. Sequence divergence distances (range 0 to 1.0) for cytochrome-b among studied populations were relatively small (0.00 to 0.55 [northern flying squirrel] and 0.00 to 0.01 [red squirrel]), so divergence may be from an historical event. Nucleotide diversity (cytochrome-b) was higher than in some other ranges (0.07 [northern flying squirrel] and 0.08 [red squirrel]); however, heterozygosity was low in the Black Hills populations. These data suggest that northern flying squirrel and red squirrel populations in the Black Hills Mountains are not only geographically disjunct, but genetically unique from their conspecifics elsewhere
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Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction - (TOPCARE-AMI)
Background - Experimental studies suggest that transplantation of blood-derived or bone marrow–derived progenitor cells beneficially affects postinfarction remodeling. The safety and feasibility of autologous progenitor cell transplantation in patients with ischemic heart disease is unknown
Food Intake of Kansans Over 80 Years of Age Attending Congregate Meal Sites
As the population of the United States continues to age, it has become increasingly more important to recognize the food intake and eating habits of older adults. The objective of this study was to describe the food group intake, factors predicting food group intake, and the food choices of community-dwelling Kansans, 80 years of age and older who participate in congregate meal programs. Participants completed a short questionnaire querying demographic information, current health status, and dietary supplement use. Participants (n = 113) were then followed up via telephone to complete two 24-hour diet recalls. Data were analyzed to determine adequacy of food group intake and mean intake. Regression analyses were used to determine factors predicting intake and frequency analysis established food typically consumed. Female participants were significantly more likely to consume more fruit servings than males. Intake was low for all five of the food groups, especially dairy. Chronic health conditions and dietary supplement use were consistently predictive factors of the amount of each food group consumed
Toward harmonized phenotyping of human myeloid-derived suppressor cells by flow cytometry: results from an interim study
There is an increasing interest for monitoring circulating myeloid-derived suppressor cells (MDSCs) in cancer patients, but there are also divergences in their phenotypic definition. To overcome this obstacle, the Cancer Immunoguiding Program under the umbrella of the Association of Cancer Immunotherapy is coordinating a proficiency panel program that aims at harmonizing MDSC phenotyping. After a consultation period, a two-stage approach was designed to harmonize MDSC phenotype. In the first step, an international consortium of 23 laboratories immunophenotyped 10 putative MDSC subsets on pretested, peripheral blood mononuclear cells of healthy donors to assess the level of concordance and define robust marker combinations for the identification of circulating MDSCs. At this stage, no mandatory requirements to standardize reagents or protocols were introduced. Data analysis revealed a small intra-laboratory, but very high inter-laboratory variance for all MDSC subsets, especially for the granulocytic subsets. In particular, the use of a dead-cell marker altered significantly the reported percentage of granulocytic MDSCs, confirming that these cells are especially sensitive to cryopreservation and/or thawing. Importantly, the gating strategy was heterogeneous and associated with high inter-center variance. Overall, our results document the high variability in MDSC phenotyping in the multicenter setting if no harmonization/standardization measures are applied. Although the observed variability depended on a number of identified parameters, the main parameter associated with variation was the gating strategy. Based on these findings, we propose further efforts to harmonize marker combinations and gating parameters to identify strategies for a robust enumeration of MDSC subsets
Timescales of spike-train correlation for neural oscillators with common drive
We examine the effect of the phase-resetting curve (PRC) on the transfer of
correlated input signals into correlated output spikes in a class of neural
models receiving noisy, super-threshold stimulation. We use linear response
theory to approximate the spike correlation coefficient in terms of moments of
the associated exit time problem, and contrast the results for Type I vs. Type
II models and across the different timescales over which spike correlations can
be assessed. We find that, on long timescales, Type I oscillators transfer
correlations much more efficiently than Type II oscillators. On short
timescales this trend reverses, with the relative efficiency switching at a
timescale that depends on the mean and standard deviation of input currents.
This switch occurs over timescales that could be exploited by downstream
circuits
FieldML
FieldML is an open format for storing and exchanging models containing field information. It is able to represent a wide variety of field value types, including scalar, vector, tensor, logical, and strings. Fields are defined over domains explicitly in terms of functions. Domains may be nested to form embedding hierarchies
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