The spectroscopic orbits and the geometrical configuration of the symbiotic binary AR Pavonis

We analyze optical and near infrared spectra of intermediate and high resolution of the eclipsing symbiotic system AR Pavonis. We have obtained the radial velocity curves for the red and the hot component from the M-giant absorption lines and from the wings of Halpha, H and He II4686 emission profiles, respectively. From the orbital elements we have derived the masses, Mgiant=2.5 and Mhot =1.0 solar masses, for the red giant and the hot component, respectively. We also present and discuss radial velocity patterns in the blue cF absorption spectrum as well as various emission lines. In particular, we confirm that the blue absorption lines are associated with the hot component. The radial velocity curve of the blue absorption system, however, does not track the hot companion's orbital motion in a straightforward way, and its departures from an expected circular orbit are particularly strong when the hot component is active. We suggest that the cF-type absorption system is formed in material streaming from the giant presumably in a region where the stream encounters an accretion disk or an extended envelope around the hot component. The broad emission wings originate from the inner accretion disk or the envelope around the hot star.We also suggest that the central absorption in H profiles is formed in a neutral portion of the cool giant's wind which is strongly concentrated towards the orbital plane. The nebula in AR Pav seems to be bounded by significant amount of neutral material in the orbital plane. The forbidden emission lines are probably formed in low density ionized regions extended in polar directions and/or the wind-wind interaction zone.Comment: 12 pages, 5 figures, accepted by A&

The Language Gap: Ideologies within Varying Communities of Practice

The “language gap” claim, originally framed by Hart and Risley, has received powerful attention throughout our society regardless of its lack of qualifications. In this paper, I explore language ideologies concerning language development throughout early childhood and its role in future academic achievement. I conducted interviews with university faculty members in Education, preschool and elementary teachers, and parents of young children in order to attain perspectives about their experience within language acquisition and socialization. In short, I found that the participant’s indicative level of expertise affected their ideologies regarding the “language gap” claim as the university faculty in Education aligned their perspectives with unnamed research and few examples of personal experience while teachers and parents more fully relied on their personal experiences. Furthermore, I offer insight on the powerful influence of ideology and the necessary reframing of linguistic differences

Black women burdening: the process of unburdening realism in Dennis McIntyre\u27s split second.

Black women who dramatize reality can experience a transference of burdens if realistic plays reflect their lived experiences. Burdens affect truthful character development and impact the mental, emotional, physical, social and spiritual well-being of Black actresses. This thesis will use the Fall 2021 University of Louisville production of Dennis McIntyre’s Split Second as a case study. Gender and Race studies along with an auto-ethnographic research approach will be used to examine how my portrayal of Alea in Split Second contributed to Black Woman Burdening, a phrase I created to examine how Black fatigue can negatively and specifically affect Black women who perform realistic theatre. This thesis offers a process for the actor to “unburden” by merging realism with the therapeutic benefits of mind, body, emotional, social, and spiritual awarenes

Epidemiological Investigations of Bighorn Sheep Respiratory Disease and Implications for Management

Infectious respiratory disease has long been identified as the cause of bighorn sheep (Ovis canadensis) historical declines and extirpations, and Mycoplasma ovipneumoniae (Movi) is the primary pathogen inducing disease and mortality. Population-level effects of pneumonia events range from mild to extirpation. Variable individual response to pathogen exposure emerges from dynamic interactions between competing evolutionary processes within the host and pathogen. Understanding impacts of this evolutionary warfare is essential to assessing long-term impacts of pathogen invasion and developing appropriate countermeasures to protect population health. Freeranging populations are faced with spillover infections from domestic sheep and goats as well as previously infected conspecifics. The introduction of a novel Movi strain from a spillover event can result in high all-age morbidity and subsequent mortality. We studied the effects of indirect and direct infection of captive bighorn sheep with Movi, a genetically diverse pathogen. We also used known Movi-carriage histories to classify ewes into 1 of 3 Movi carrier classes. We tested the hypothesis that respiratory disease persistence within bighorn sheep populations is driven by chronically Movi infected ewes, and the prediction that lambs born in pens with at least one chronic carrier ewe (treatment) would experience Movi-induced pneumonia mortality whereas lambs born in pens without a chronic carrier ewe (control) would not develop fatal pneumonia. When all mortality causes were pooled across all years of our study, the percentage of lambs that did not survive was more than twice as high when lambs were in born in pens containing at least one Movi chronic shedder ewe (treatment), compared to when only Movi negative and/or intermittent ewes were present in the pen (control; 92% (n = 33 of 36) and 38% (n = 5 of 13). The mean probability of pneumonia-induced mortality for commingled lambs was above 0.75 by 15 days of age and generally remained above that level for the duration of the study. Our model also estimated this probability to be elevated (≥ 0.90) as early as 16 days of age until 45 days of age, and a secondary peak for older, nearly weaned, lambs (105–114 days of age). While conducting a study for Movi detection probability in serial samples, we document unilateral Movi colonization and direct managers on field sampling techniques for reliable disease surveillance of bighorn sheep populations. Our results suggest that active disease control efforts must account for multiple Movi strains to prevent spillover epidemics. Our results also underscore that removal of chronic carriers from a population will aid bighorn sheep recovery efforts

Not (Just) Donne: Alchemical Transmutation as Immortality in Shakespeare’s Sonnets

Shakespeare, in his sonnets, employs alchemical references in the sonnets that ultimately fail, in order to show how fruitless it is to pursue immortality. The poet urges the fair friend, who himself is like the self-consuming ouroboros, to father a child that will continue his legacy and allow the fair friend to live on via the child. Language associated with the child is alchemical, referencing distillation, vials, flasks, and the renewing power of the philosopher’s stone. The dark lady, the opposite of the fair friend in every way, can be explained as fulfilling alchemy’s union of opposites needed for a philosopher’s stone to be created. However, when the fabled medicinal baths cannot cure the poet of the ill love he has contracted from the dark lady, it becomes clear that, just as there is no philosopher’s stone, there is no immortality

Saenger Theatre: for-profit arts organization

The following report describes the activities and outcomes of a fourteen-week internship in the fall of 2004 in the Marketing, Booking & Special Events and Group & Corporate Sales Departments of the Saenger Theatre. The first section contains an organizational profile. The second is a detailed description of the internship. The third section is an analysis of the internal and external problems within the organization. The fourth is an explanation of the Best Practices found within the organization and any recommendations for the resolution of challenges. The conclusion of the report contains a discussion of the short and long term effects of the intern\u27s contributions to the organization

T Cell Responsiveness Through the Ages: Functional Diversity of Age-Dependent Antiviral Responses

An organism’s age impacts its susceptibility to disease, which varies according to the type of insult or causal pathogen. Much work remains to delineate these complexities, especially within younger individuals. Indeed, pediatric disease-driven immunity is less characterized than adult and aging populations due to two main factors: 1) descriptions through multiple stages of development are required, as the immune system undergoes massive changes from gestation through the end of adolescence, and 2) the complex nature of pediatric research decreases the availability of robust and comprehensive studies. Importantly, studying the immune system in relation to age requires a foundational knowledge within adult individuals to adequately assess the unique characteristics of the developing and aged systems. This body of work contributes to the field of age-dependent immunity via the study of repair-associated T cell subsets in pediatric acute respiratory distress syndrome (pARDS), γδ T cells in murine cytomegalovirus (MCMV), and multiple immune mediators and cell populations in adult severe influenza infection. Single-cell RNA sequencing of tracheal aspirate cells from pediatric subjects experiencing acute respiratory failure (ARF) showed that distinct T cell subsets within the lower respiratory tract exhibited transcriptional similarity, termed functional redundancy. This similarity was repair-associated, and a defining gene of the transcriptional profile was amphiregulin (AREG). When quantified, T cells from subjects with a viral lower respiratory tract infection (LRTI) that did not progress to moderate or severe pARDS had significantly elevated repair scores. This was reflected within tissue resident memory (TRM) CD8 T cells, activated regulatory CD4 T cells (Tregs), and activated AREG+ γδ T cells. The repair profile was then applied across publicly available datasets spanning ages, tissue types, etiologies, and severities, and functional redundancy was only observed within the same three subsets of tracheal aspirate T cells from healthy pediatric subjects. Additional validation confirmed that nasal wash supernatant proteins from the repair profile were inversely correlated with age. Collectively, these findings indicated that T cells within the respiratory tract exhibited functional redundancy linked to tissue repair in an age-dependent manner, and that this redundancy was associated with decreased disease severity. Results from mouse models of MCMV infection demonstrated that the functionality of γδ T cells is shaped by infection in an age-specific manner. γδ T cells from neonates infected with MCMV underwent a shift in cytokine production that was absent in acutely infected adult, aged, and geriatric mice. Neonatal infection also affected the γδ T cell receptor (TCR) repertoire by modulating the hierarchy of segment usage. Single-cell RNA sequencing with paired TCR repertoire data from the lungs showed that both age and MCMV infection impacted γδ T cells in a manner determined by age of viral exposure, viral state, and age of the mouse at endpoint characterization. These data highlight age-associated functionality of γδ T cells in MCMV infection, and the role that age of exposure plays in shaping γδ T cell immunity. Lastly, a cohort of oseltamivir-treated adults with severe influenza infection were utilized to address 3 questions: 1) What is the relationship between patient risk and severity scores throughout severe influenza infection? 2) What immunological features underlay severe influenza infection? 3) What immune biomarkers are predictive of infection severity and clinical outcome? First, assessment of the relationship between risk and severity scores showed increased correlation between metrics that incorporated supplemental oxygen usage, as well as those which were less subjective in nature. No correlations were observed for intake risk metrics or subjective severity scoring. Second, a decrease in protection-associated cytokines and innate immune mediators was observed over the course of severe infection across all individuals. Additionally, subjects with heightened severity exhibited decreased upper respiratory and peripheral pro-inflammatory and pleiotropic cytokines at study day 0, decreased T cells spanning naive and memory phenotypes at study days 0, 3, and 28, and decreased peripheral eotaxin at study day 28. Third, peripheral myeloid analytes were positively associated with severity based on intake vitals, while cytotoxic natural killer T (NKT) cells were negatively associated. Multiple circulating and upper respiratory cytokines were predictive of peak infection severity, as was the frequency of circulating eosinophils. For correlative analyses, age was included in all linear regression modeling, since the study included both adult and elderly individuals. In conclusion, these data established the presence of functionally redundant pediatric T cells in the airway, identified age-associated features of γδ T cells in MCMV-infected lungs, and laid the foundation for studies of severe influenza infection in antiviral-treated individuals across different ages. The unique functions of pediatric T cells in this body of work widen the scope of future age-associated immune studies, which will impact study design, interpretation, and subsequent therapeutic development