Cleft lip palate in Cape Town

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Evaluation of the Impact of the Watu Ata Nature Reserve Policy Setting

The major theme of this paper is to evaluate policy impacts. This paper aims to evaluate the impact of the determination of the Watu Ata Nature Reserve using the evaluation criteria proposed by William N. Dunn: Effectiveness, Equity, Responsiveness and Appropriateness. As defined in RI Government Regulation No. 28 of 2011 Article 1, a nature reserve is an area which, due to its natural condition, contains unique plants and/or plant diversity along with natural phenomena and whose ecosystem requires protection and preservation efforts so that its existence and development can grow naturally. The Watu Ata Nature Reserve is one nature reserve area in the Ngada regency based on the Decree of Minister of Forestry No. 432/Kpts-II/92. The research method used is a descriptive qualitative study that employs a field study approach conducted in two villages, namely, Heawea Village and Inelika Village. These two villages have the biggest community's land in the Watu Ata Nature Reserve. The findings suggest that the Watu Ata Nature Reserve policy has had a negative impact on people living around the nature reserve area, particularly with respect to their loss of access to the cultivated land and cultural sites where they have built relationships with their deceased ancestors

Using ceftazidime-avibactam for persistent carbapenem-resistant Serratia marcescens infection highlights antimicrobial stewardship challenges with new beta-lactam-inhibitor combination antibiotics

The newer beta-lactam-inhibitor combination (BLIC) antibiotics are available in South Africa (SA) for the treatment of carbapenem-resistant Enterobacterales infections. We describe the successful use of ceftazidime-avibactam (CA) for the treatment of a child with persistent carbapenem-resistant Serratia marcescens bacteraemia, and the challenges faced using this lifesaving antibiotic, including access to susceptibility testing, procurement process, cost and complexity of deciding when, how and for how long to use it. Furthermore, the burden of carbapenem resistance is increasing in SA, and inappropriate use of CA and other newer BLIC antibiotics, such as ceftolozane-tazobactam, will inevitably endanger their longevity. A careful balance must be struck between removing unnecessary obstacles and delays in initiating these antibiotics for life-threatening infections, and additional antimicrobial stewardship-guided interventions aimed at preserving their therapeutic use

The efficacy of a generic doxycycline tablet in the treatment of canine monocytic ehrlichiosis

The objective of the present study was to evaluate the therapeutic efficacy of a generic doxycycline tablet (DoxyVet®) against Ehrlichia canis infection in dogs. Canine monocytic ehrlichiosis is caused by the bacterium E. canis and transmitted by the brown kennel tick (Rhipicephalus sanguineus). Six disease-free and tick-free dogs were infested with E. canisinfected ticks. Once diagnosed (with polymerase chain reaction [PCR] analysis and platelet counts) as positive for infection, doxycycline tablets were administered orally once a day for 20 consecutive days, at a target dose level of 10 mg/kg. The actual dose administered was calculated as ranging between 10 mg/kg and 11.7 mg/kg. The PCR analysis, 28 days after the first administration of the tablets, failed to detect E. canis in any of the dogs. On Day 56 of the study, four of the dogs were diagnosed with E. canis for the second time and a fifth dog was diagnosed on Day 70. The platelet counts of the sixth dog remained within normal levels and it was discharged from the study on Day 84. Doxycycline tablets were then administered to the remaining five infected dogs for 28 consecutive days. Four of these dogs had no positive PCR results during the following 3 months. The fifth dog was diagnosed with E. canis for the third time 58 days after the last tablets of the second treatment had been administered, after which it was rescue treated (doxycycline for a further 28 days). The results indicate that doxycycline administered in tablet form (DoxyVet®) at 10 mg/kg – 11.7 mg/kg body mass once daily for 28 consecutive days clears most dogs of infection. The importance of a concomitant tick-control programme is therefore stressed

Health professions students' interprofessional experiences on a rural learning platform

HEALTH PROFESSIONS STUDENTS’ LEARNING EXPERIENCES ON A RURAL COLLABORATIVE LEARNING PLATFORM ABSTRACTA Faculty of Health Sciences launched a rural collaborative learning platform to cultivate interprofessional key competencies and to improve health outcomes. The purpose of the study was to describe health sciences students’ experiences of an rural collaborative learning platform. Health professions students created digital stories reflecting on their collaborative learning experiences. Purposive sampling resulted in 23 submissions. Qualitative analysis of content identified themes and categories. Three themes, namely, metaphor, critical consciousness and professional socialisation, were identified. The metaphor categories, Journey, Setting world ablaze, Water, and Puzzle, represent students’ desire to use visual cues to describe their experiences. Transformation, Personal development and Empathy signified critical consciousness. Collaborative practice, Values, Reflective practice, and Key competencies relate to professional socialisation. The researchers gained understanding of students’ experiences on an rural collaborative learning platform. Through digital stories, students became aware of professional interdependency, which linked their experiences to key interprofessional competencies.

A comparison of multiple luminescence chronometers at Voordrag, South Africa

A suite of 10 samples collected from an 11 m thick colluvial sequence at Voordrag, KwaZulu-Natal, South Africa, have been used to undertake a comparison of different luminescence methods. Good agreement is found between single grain quartz optically stimulated luminescence (OSL) and single grain K-feldspar post-infrared infrared-stimulated luminescence (post-IR IRSL) ages, with the exception of the basal samples where the quartz OSL signal is saturated. Multiple grain quartz OSL consistently yields ages older than single grain OSL methods. Multiple grain feldspar ages derived from the IRSL50 signal are underestimated due to anomalous fading. A previously published radiocarbon chronology yields ages that are younger than those from single grain quartz OSL and post-IR IRSL, and this is most likely due to contamination with younger carbon. Identifying the effect of saturation on the quartz OSL signal remains challenging when quartz is dated in isolation. However, using a paired quartz/feldspar dating approach is an effective way of identifying the impact of saturation on the OSL signal

Suicide cases investigated at the state mortuary in Bloemfontein, 2003–2007

Background: Up to 8 000 South Africans commit suicide annually. This study aimed to investigate the profile of suicide cases in Bloemfontein and the southern Free State province.Methods: A cross-sectional descriptive study was performed. Suicides in the Bloemfontein and southern Free State areas (Xhariep and Motheo districts) investigated at the state mortuary in Bloemfontein in 2003 to 2007 were included. Data were collected retrospectively by using a specially designed data-capturing form.Results: A total of 469 suicide cases were included in the study. The estimated suicide rate for this part of the Free State province was 10.9/100 000 of the population per year. The majority (82.1%) of the victims were men. In total, 338 (72.1%) of the victims were black, 122 (26.0%) were white, five (1.1%) were coloured and three (0.6%) were Indian. The most common methods were hanging (262; 55.9%), shooting (99; 21.1%) and overdosing on pills (43; 9.2%). Most cases (57.8%) occurred in victims 21 to 40 years of age. Five (1.1%) victims were children younger than 11 years of age, while 12 (2.6%) were older than 65 years. More than half (267 cases; 56.9%) of the suicide victims were unemployed. The majority(43.1%) of suicides occurred in January to April of each year, with the highest incidence (67 cases; 14.3%) in January. Conclusion: The rate of suicide and the profile of victims with regard to the variables investigated corresponded to findings reported from other studies. The information obtained could make a meaningful contribution to suicide-preventionprogrammes.Keywords: suicide; profile; rate; prevention; Free State Provinc

Sexual Activity, Knowledge of Contraceptives Use a mong Females Choosing Termination of Pregnancy at a Provincial Clinic in South Africa

This study investigated sexual activity, knowledge of contraceptives use among females choosing termination of pregnancy (TOP) at a provincial clinic in South Africa. This was a quantitative and observational study in the form of a cross-sectional survey. A pre-tested self-administered questionnaire was used to collect data from 61 respondents who had terminated their pregnancies. Almost ninety-two (91.8%) percent of the respondents were single women between 18 and 27 years of age. Their level of education showed that 32% had completed high school, 28% were high school learners, 21.1% were tertiary education level learners and 1.8% had tertiary education. The frequency of sexual activity was mostly once a month (40%), followed by once a week (36.5%). Unemployment was high (36%), making the respondents dependent on government grants. Most of the women were aware of contraceptives methods (88.5%). The majority of the respondents (75.4%) have heard about emergency contraceptives (EC), while only 11.5% had never heard of contraceptives in general. The condom was the most popular method (54.1%), followed by the injection (45.9%). However, although 88.5% and 75.4% have heard of emergency contraceptives, their knowledge of contraceptives in general was very low. Contraceptives were used by 78.6% before termination of their pregnancy (TOP) and the most frequently used method was the injection at 36.6%. The respondents were the initiators of TOP. The researchers recommended that awareness of contraceptives should be promoted, and programmes aimed at changing the behaviour of sexually active females should be designed in order for them to make use of reproductive health services and family planning. Continuous education on sexual activities and contraceptives needs to be given to women visiting a reproductive health clinic. Policymakers should facilitate access to modern contraceptives and promote their effectiveness in all disadvantaged communities, thus addressing the root cause of the termination of unplanned pregnancies.Health Studie