Democracy at Work: The Sixth Circuit Upholds The Right of the People of Cincinnati to Choose Their Own Morality in \u3ci\u3eEquality Foundation of Greater Cincinnati, Inc. v. City of Cincinnati\u3c/i\u3e, 128 F.3d 289 (6th Cir. 1997)

The gay-rights movement, which has grown in power and influence over the last few decades, can no longer proclaim political powerlessness. The great proliferation of gay-rights groups and anti-discrimination laws and policies demonstrate this. Gay-rights organizations have had much success in promoting an agenda of tolerance and non-discrimination across America. The gay-rights movement, however, has since changed its goals from societal tolerance of homosexuals to outright acceptance even to the extent of legalizing same-sex marriage. Supporters of traditional mores, however, have begun to fight back. The public is responding to what it sees as an elitist court system that imposes its own liberal morality onto the populace against their will. The opponents of such radical social engineering by an un-elected few have responded with successful grass-roots democratic efforts to thwart this attack on traditional morality and return this nation \to its historic roots. This Note will examine one such effort by the citizens of Cincinnati and the litigation that resulted from it in the case Equality Foundation of Greater Cincinnati, Inc. v. City of Cincinnati

Test and evaluation of load converter topologies used in the Space Station Freedom Power Management and distribution DC test bed

Power components hardware in support of the Space Station Freedom dc Electrical Power System were tested. One type of breadboard hardware tested is the dc Load Converter Unit, which constitutes the power interface between the electric power system and the actual load. These units are dc to dc converters that provide the final system regulation before power is delivered to the load. Three load converters were tested: a series resonant converter, a series inductor switchmode converter, and a switching full-bridge forward converter. The topology, operation principles, and tests results are described, in general. A comparative analysis of the three units is given with respect to efficiency, regulation, short circuit behavior (protection), and transient characteristics

Supervisory advanced control of glass melters and forehearths by the GS expert system

Advanced control is one of the most important tools to increase glass quality and production in existing furnaces. This paper describes a method of how advanced control has been applied in glass industry. Practical experience of an advanced control system called EXPERTSystem II is shown and explained. The present state of control in the glass industry is relatively poor compared to other chemical industries, therefore the potential increase in benefits by advanced control systems is very high for the glass production system

Comparative risk science for the coronavirus pandemic

© 2020 Informa UK Limited, trading as Taylor & Francis Group. Dette er den aksepterte versjonen av en artikkel publisert i Journal of Risk Research. Du finner den publiserte artikkelen her: https://doi.org/10.1080/13669877.2020.1756384 / This is the postprint version of the article published in Journal of Risk Research. You can find the published article here. https://doi.org/10.1080/13669877.2020.1756384Judgment, decision making, and risk researchers have learned a great deal over the years about how people prepare for and react to global risks. In recent years, risk scholars have increasingly focused their energies on climate change, and as pandemic coronavirus has swept the globe many of these scholars are comparing the coronavirus pandemic with climate change to inform risk management. Risk communication research and the best practices developed from it are predicated on findings from the 1970’s to the present showing that there are structural similarities in how people think about widely divergent risks. Consequently, these lessons from risk communication of climate change (and from the canon of best practices) apply to the coronavirus pandemic. In the empirical comparison of student perceptions reported here, we replicate these structural similarity findings, but also find that moral concerns in particular deserve attention as a potentially distinct dimension of risk perception, on which different risks may also differ, as pandemic risks appear to evoke less moral concern than climate change. The need for communications to be timely, honest, credible, empathetic, and informative for useful individual actions is fundamental and essential for communicating effectively about the coronavirus epidemic. Some countries have heeded risk sciences, and are coping more successfully with pandemic coronavirus. Others have failed to implement these old lessons, which our data suggest still apply. While these failures may reinforce cynicism about political and public enthusiasm for accepting science, comparisons between the coronavirus pandemic and climate change may also foster greater aspirations for collective action.acceptedVersio

La Citometría de flujo en el análisis citómico: in vivo, in vitro, ¿in fluxo?

La Citometría de flujo en el análisis citómico: in vivo, in vitro, ¿in fluxo

Model Lessons to Use With The Student Atlas of Oregon

Model lessons for teachers to use with The Student Atlas of Oregon.https://pdxscholar.library.pdx.edu/geographyed_instructional/1001/thumbnail.jp

Modifying the m6A brain methylome by ALKBH5-mediated demethylation: a new contender for synaptic tagging

Synaptic plasticity processes, which underlie learning and memory formation, require RNA to be translated local to synapses. The synaptic tagging hypothesis has previously been proposed to explain how mRNAs are available at specific activated synapses. However how RNA is regulated, and which transcripts are silenced or processed as part of the tagging process is still unknown. Modification of RNA by N6-methyladenosine (m6A/m) influences the cellular fate of mRNA. Here, by advanced microscopy, we showed that m6A demethylation by the eraser protein ALKBH5 occurs at active synaptic ribosomes and at synapses during short term plasticity. We demonstrated that at activated glutamatergic post-synaptic sites, both the YTHDF1 and YTHDF3 reader and the ALKBH5 eraser proteins increase in co-localisation to m6A-modified RNAs; but only the readers showed high co-localisation to modified RNAs during late-stage plasticity. The YTHDF1 and YTHFDF3 readers also exhibited differential roles during synaptic maturation suggesting that temporal and subcellular abundance may determine specific function. m6A-sequencing of human parahippocampus brain tissue revealed distinct white and grey matter m6A methylome profiles indicating that cellular context is a fundamental factor dictating regulated pathways. However, in both neuronal and glial cell-rich tissue, m6A effector proteins are themselves modified and m6A epitranscriptional and posttranslational modification processes coregulate protein cascades. We hypothesise that the availability m6A effector protein machinery in conjunction with RNA modification, may be important in the formation of condensed synaptic nanodomain assemblies through liquid-liquid phase separation. Our findings support that m6A demethylation by ALKBH5 is an intrinsic component of the synaptic tagging hypothesis and a molecular switch which leads to alterations in the RNA methylome, synaptic dysfunction and potentially reversible disease states

Chondromyxoid Fibroma of the Skull Base Invading the Occipitocervical Junction: Report of a Unique Case and Discussion

Chondromyxoid fibroma (CMF) is a rare bone tumor representing less than 1% of total bone neoplasms. It is a slow-growing, locally destructive tumor that usually affects the metaphyseal region of long bones. The occurrence of this tumor in the skull base or cervical spine is exceptionally rare. We present the first case of CMF originating in the clivus and extending into the atlas and discuss the surgical management of this case