A kernel-based framework for medical big-data analytics

The recent trend towards standardization of Electronic Health Records (EHRs) represents a significant opportunity and challenge for medical big-data analytics. The challenge typically arises from the nature of the data which may be heterogeneous, sparse, very high-dimensional, incomplete and inaccurate. Of these, standard pattern recognition methods can typically address issues of high-dimensionality, sparsity and inaccuracy. The remaining issues of incompleteness and heterogeneity however are problematic; data can be as diverse as handwritten notes, blood-pressure readings and MR scans, and typically very little of this data will be co-present for each patient at any given time interval. We therefore advocate a kernel-based framework as being most appropriate for handling these issues, using the neutral point substitution method to accommodate missing inter-modal data. For pre-processing of image-based MR data we advocate a Deep Learning solution for contextual areal segmentation, with edit-distance based kernel measurement then used to characterize relevant morphology

Comparison of several methods for predicting separation in a compressible turbulent boundary layer

Several methods for predicting the separation point for a compressible turbulent boundary layer were applied to the flow over a bump on a wind-tunnel wall. Measured pressure distributions were used as input. Two integral boundary-layer methods, three finite-difference boundary-layer methods, and three simple methods were applied at five free-stream Mach numbers ranging from 0.354 to 0.7325. Each of the boundary-layer methods failed to explicitly predict separation. However, by relaxing the theoretical separation criteria, several boundary-layer methods were made to yield reasonable separation predictions, but none of the methods accurately predicted the important boundary-layer parameters at separation. Only one of the simple methods consistently predicted separation with reasonable accuracy in a manner consistent with the theory. The other methods either indicated several possible separation locations or only sometimes predicted separation

An analysis for the sound field produced by rigid wide cord dual rotation propellers of high solidarity in compressible flow

An unsteady lifting service theory for the counter-rotating propeller is presented using the linearized governing equations for the acceleration potential and representing the blades by a surface distribution of pulsating acoustic dipoles distributed according to a modified Birnbaum series. The Birnbaum series coefficients are determined by satisfying the surface tangency boundary conditions on the front and rear propeller blades. Expressions for the combined acoustic resonance modes of the front prop, the rear prop and the combination are also given

Method for the determination of the three-dimensional aerodynamic field of a rotor-stator combination to compressible flow

Using the lifting surface theory and the acceleration potential method for the flow field of an axial turbocompressor stage, a recursive and a direct method are presented that make use of the eigenfunction solutions of the isolated rotor and stator to solve for the rotor-stator interaction problem. The net pressure distribution on the rotor and stator blades is represented by modified Birnbaum series, whose coefficients are determined using a matrix procedure and satisfying the boundary conditions on the surface of the blades. The relation between the matrix operators of the recursive and the direct methods is also shown. Expressions have been given for the blade circulation, the axial and tangential forces on the blade, the rotor power required, and the induced upwash velocity of the stage

Design-thinking, making, and innovating: Fresh tools for the physician\u27s toolbox

Medical school education should foster creativity by enabling students to become \u27makers\u27 who prototype and design. Healthcare professionals and students experience pain points on a daily basis, but are not given the tools, training, or opportunity to help solve them in new, potentially better ways. The student physician of the future will learn these skills through collaborative workshops and having dedicated \u27innovation time.\u27 This pre-clinical curriculum would incorporate skills centered on (1) Digital Technology and Small Electronics (DTSE), (2) Textiles and Medical Materials (TMM), and (3) Rapid Prototyping Technologies (RPT). Complemented by an on-campus makerspace, students will be able to prototype and iterate on their ideas in a fun and accessible space. Designing and making among and between patients and healthcare professionals would change the current dynamic of medical education, empowering students to solve problems in healthcare even at an early stage in their career. By doing so, they will gain empathy, problem-solving abilities, and communication skills that will extend into clinical practice. Our proposed curriculum will equip medical students with the skills, passion, and curiosity to impact the future of healthcare

Large-scale advanced propeller blade pressure distributions: Prediction and data

Two Euler analyses techniques, finite difference and finite volume, were employed to predict the blade surface pressure distributions of a large scale advanced propeller. The predicted pressure distributions were compared with wind tunnel data. Both techniques produced blade pressure distributions that are in fairly good agreement with the data over the range of test Mach numbers of 0.2 to 0.78. However, the numerical simulations fail to predict correctly the measured pressure distributions for the low Mach number, high power case. The data indicate the presence of a leading edge vortex for this case. A discussion of the compressibility effects is also presented

Strontium optical lattice clocks for practical realization of the metre and secondary representation of the second

We present a system of two independent strontium optical lattice standards probed with a single shared ultra-narrow laser. The absolute frequency of the clocks can be verified by the use of Er:fiber optical frequency comb with the GPS-disciplined Rb frequency standard. We report hertz-level spectroscopy of the clock line and measurements of frequency stability of the two strontium optical lattice clocks.Comment: This is an author-created, un-copyedited version of an article accepted for publication in Meas. Sci. Technol. The publisher is not responsible for any errors or omissions in this version of the manuscript or any version derived from it. The Version of Record is available online at doi:10.1088/0957-0233/26/7/07520