High-Pressure Injection Injury of the Face: A Case Report on Presentation and Management

Introduction: High-pressure injection injuries have been chronicled for decades.1 These injuries often affect distal extremities as they are most commonly involved in workplace accidents.1 However, we discuss a young male with a paint-gun injection injury to his face.Case Report: We discuss the case of a young man presenting to the emergency department after high-pressure injection injury to the face. He eventually underwent extensive debridement of the face. We discuss differences in caring for an injection wound to an extremity versus the face, including time sensitivity of treatment, initial stabilizing measures, and critical steps.Discussion: This case demonstrates a rare presentation of a high-pressure paint injection injury. This injury presented a unique surgical challenge where, despite compartment syndrome being less common, cosmetic outcome and infectious complication prevention remained critical priorities.Conclusion: While similarities exist in management of an injection injury to a limb, due to the rarity and deceptive appearance of this particular injury to the face, high suspicion along with urgent imaging and surgical consultation is warranted

Evaluating State Anxiety Levels in Nursing Students

Anxiety, dependent upon the frequency and severity, can be a serious problem that reduces physical, cognitive, and clinical performance. Nursing students have been found to experience especially high levels of state and trait anxiety which, according to Dorothea Orem’s self-care deficit theory, causes a deficit in health promotion and the health of oneself. There is little evidence available about how progression through a baccalaureate nursing program in the United States impacts anxiety. This research investigates anxiety in baccalaureate nursing students and how progression through the program influences self-reported anxiety levels. A descriptive cross-sectional study was performed on a convenience sample at a Midwestern public university in the United States via an online survey, which included both demographic questions and the Generalized Anxiety Disorder 7-item scale (GAD-7). It was determined statistically significant that sophomore students have a higher level of anxiety compared to junior and senior year nursing students. There is also a positive correlation between GPA and GAD-7 scores. Education for sophomore nursing students focused on improved familiarity with the program is discussed as a possible solution for high anxiety levels in this cohort

Capital Based Sustainability Indicators as a Possible Way for Measuring Agricultural Sustainability

This paper takes the capital based approach to sustainability and applies this to examine the sustainability of different farming methods. The capital based approach argues that for future generations to be as well off as the present than the capital base should at least be maintained. The paper explores some of the issues around this approach such as the definition of capitals, their measurement and weakness in the approach which do not account for the resilience of system and/ or the substitutability of capitals. The paper outlines how this could be applied to agriculture and show sustainability across different farming methods. The data used is from the ARGOS (Agricultural Research Group on Sustainability) project which has collected data on social, economic and environmental factors from kiwifruit orchards green, green organic and gold, for five years. The results show little significant differences across orchard types. This may be due to the homogeneity of kiwifruit orchards and it is intended to expand this to the sheep sector to examine this further.Agricultural and Food Policy,

Potent CRISPR-Cas9 inhibitors from Staphylococcus genomes.

Anti-CRISPRs (Acrs) are small proteins that inhibit the RNA-guided DNA targeting activity of CRISPR-Cas enzymes. Encoded by bacteriophage and phage-derived bacterial genes, Acrs prevent CRISPR-mediated inhibition of phage infection and can also block CRISPR-Cas-mediated genome editing in eukaryotic cells. To identify Acrs capable of inhibiting Staphylococcus aureus Cas9 (SauCas9), an alternative to the most commonly used genome editing protein Streptococcus pyogenes Cas9 (SpyCas9), we used both self-targeting CRISPR screening and guilt-by-association genomic search strategies. Here we describe three potent inhibitors of SauCas9 that we name AcrIIA13, AcrIIA14, and AcrIIA15. These inhibitors share a conserved N-terminal sequence that is dispensable for DNA cleavage inhibition and have divergent C termini that are required in each case for inhibition of SauCas9-catalyzed DNA cleavage. In human cells, we observe robust inhibition of SauCas9-induced genome editing by AcrIIA13 and moderate inhibition by AcrIIA14 and AcrIIA15. We also find that the conserved N-terminal domain of AcrIIA13-AcrIIA15 binds to an inverted repeat sequence in the promoter of these Acr genes, consistent with its predicted helix-turn-helix DNA binding structure. These data demonstrate an effective strategy for Acr discovery and establish AcrIIA13-AcrIIA15 as unique bifunctional inhibitors of SauCas9

Business strategies and employment decisions: Interviews with New Zealand firms

A firm’s business strategy does not exist in a vacuum; it requires employees to implement it. However, firms often say that they have difficulties hiring certain types of employees. Through interviews with firms and analysis of the 2008 New Zealand Business Operations Survey, this research explored the interaction between strategy and employees’ skills, and differences between high value-add (HVA) and medium value-add (MVA) firms. MVA firms focused more on production methods, technical skills, and margins over costs. HVA firms focused more on the business skills of a few, professional core employees, as well as the marketing aspects of their products.The research was conducted with funding from the Ministry of Economic Development and the Cross- Department Research Pool (CDRP)

The ManVan:a mobile cancer support service for men with prostate, testicular and penile cancer in Wales

The ManVan commenced service delivery on 1st April 2014 and is the United Kingdom’s first dedicated mobile support service for men affected by prostate, testicular, and penile cancer. It is delivered in partnership with Prostate Cancer UK and Movember and fully funded by the Movember Foundation. It brings nursing care, counselling for individuals and couples, group support and welfare rights advice, directly to men living with prostate, testicular and penile cancer in communities across Wales. The ManVan has travelled extensively across Wales during its first year, visiting 94 different locations, across all seven Local Health Board areas. The first half of the year began with a Roadshow where we welcomed thousands of visitors on board, including men and women worried by all sorts of cancer symptoms; their family and friends; health and social care professionals and politicians. The variety of venues the ManVan has visited has included hospitals, supermarkets, social clubs, caravan fairs and rugby grounds to help raise awareness of the ManVan service and identify potential clients. As expected the greatest proportion of visitors are male, particularly older men. In the second half of the year, we focussed on our target audience – men diagnosed with prostate, testicular, or penile cancer and their families. Using a targeted approach to urology clinics across NHS Wales, as well as community-based activity encouraging men from ethnic minorities to visit, we have now taken on 161 clients, many of whom have received more than one ManVan service, and attended on more than one occasion. Most of our clients have prostate cancer, are over the age of 55 years, and are married. Analysis of the early data around the clinical and psychosocial benefits of the services offered on the ManVan is positive and the annualised value of the benefits obtained for ManVan clients equates to more than £300,000 in this first year. There were 3,319 visitors to the ManVan in total during the first year

Rocky River Elementary School Case Study

The case study titled "Rocky River Elementary School: An Implementation of a Social-Emotional Learning (SEL) Curriculum and Sensory Integration Tools for All Students" provides insight into the implementation of a social-emotional learning (SEL) curriculum and sensory integration tools at Rocky River Elementary School. The purpose of this study was to understand the impact of this program on students' social-emotional development, academic performance, and behavior. The study provides a comprehensive overview of the SEL curriculum and sensory integration tools that were used, the steps taken to implement the program, and the results observed after the implementation

Nominal juxtaposition in Australian languages: An LFG analysis

It is well known that Australian languages make heavy use of nominal juxtaposition in a wide variety of functions, but there is little discussion in the theoretical literature of how such juxtapositions should be analysed. We discuss a range of data from Australian languages illustrating how multiple nominals share a single grammatical function within the clause. We argue that such constructions should be treated syntactically as set-valued grammatical functions in Lexical-Functional Grammar (LFG). Sets as values for functions are well-established in LFG and are used in the representation of adjuncts, and also in the representation of coordination. In many Australian languages, coordination is expressed asyndetically, that is, by nominal juxtaposition with no overt coordinator at all. We argue that the syntactic similarity of all juxtaposed constructions (ranging from coordination through a number of more appositional relations) motivates an analysis in which they are treated similarly in the syntax, but suitably distinguished in the semantics. We show how this can be achieved within LFG, providing a unified treatment of the syntax of juxtaposition in Australian languages and showing how the interface to the semantics can be quite straightforwardly defined in the modular LFG approach. Copyright © Cambridge University Press 2009