Impact of Home-Based Management of malaria combined with other community-based interventions: what do we learn from Rwanda?

Introduction: This study aimed to evaluate the impact of home-based management of malaria (HBM) strategy on time to treatment and reported presumed malaria morbidity in children aged less than 5 years in Rwanda. Methods: The study was carried out in two malaria-endemic rural districts, one where HBM was applied and the other serving as control. In each district, a sample of mothers was surveyed by questionnaire before (2004) and after (2007) implementation of HBM. Results: After implementation, we observed: i) an increase (P<0.001) in the number of febrile children treated within 24 hours of symptom onset in the experimental district (53.7% in 2007 vs 5% in 2004) compared with the control district (28% vs 7.7%); ii) a decrease in the reported number of febrile children in the experimental district (28.7% vs 44.9%, P<0.01) compared with the control district (45.7% vs 56.5%, P<0.05). Conclusion: HBM contributed to decrease time to treatment and reported presumed malaria morbidity.Pan African Medical Journal 2013; 14:5

Impact of implementing performance-based financing on childhood malnutrition in Rwanda

Background: Malnutrition remains a serious concern in Rwanda, particularly among children under-5 years. Performance-based financing (PBF), an innovative health systems financing strategy, has been implemented at the national level since 2008. This study aimed to assess the impact of PBF and other factors associated with the prevalence of three classifications of malnutrition (stunting, wasting and underweight) in children under-5 years in Rwanda. Methods: The study is a cross-sectional study comprising of 713 children under five years old from 557 households, whose anthropometric measurements (height, weight and age) had been obtained as part of the 2008 Rwanda General Health and HIV household survey. Z-scores for height-for-age, weight-for-age, weight-for-height, and body mass index-for-age were analyzed according to the World Health Organization 2006 Child Growth Standards. Random intercept logistic regression models were used to regress each anthropometric measure (WAZ, HAZ and WHZ) against child, maternal and household characteristics. Results: Child participants ranged in age from 0 to 60 months, 20.2% of children were under 12 months and 5.1% were HIV positive. The prevalence of wasting was 8.8%; of stunting was 58.4%; and of underweight status was 20.7%. Maternal emotional and social wellbeing was protective of wasting in children under-5 years of age. Living in districts implementing PBF was protective of wasting (Adjusted Odds Ratio: 0.43; 95% confidence interval: 0.19-0.97). Living in a district with PBF was not found to be associated with either stunting or underweight status among children under-5. Conclusions: PBF may have a protective association with particular forms of malnutrition among children under-5 years in Rwanda. These findings warrant further investigation in relation to the impact of implementing innovative financing schemes on health outcomes

HIV-free survival among nine- to 24-month-old children born to HIV-positive mothers in the Rwandan national PMTCT programme: a community-based household survey

<p>Abstract</p> <p>Background</p> <p>Operational effectiveness of large-scale national programmes for the prevention of mother to child transmission (PMTCT) of HIV in sub-Saharan Africa remains limited. We report on HIV-free survival among nine- to 24-month-old children born to HIV-positive mothers in the national PMTCT programme in Rwanda.</p> <p>Methods</p> <p>We conducted a national representative household survey between February and May 2009. Participants were mothers who had attended antenatal care at least once during their most recent pregnancy, and whose children were aged nine to 24 months. A two-stage stratified (geographic location of PMTCT site, maternal HIV status during pregnancy) cluster sampling was used to select mother-infant pairs to be interviewed during household visits. Alive children born from HIV-positive mothers (HIV-exposed children) were tested for HIV according to routine HIV testing protocol. We calculated HIV-free survival at nine to 24 months. We subsequently determined factors associated with mother to child transmission of HIV, child death and HIV-free survival using logistic regression.</p> <p>Results</p> <p>Out of 1448 HIV-exposed children surveyed, 44 (3.0%) were reported dead by nine months of age. Of the 1340 children alive, 53 (4.0%) tested HIV positive. HIV-free survival was estimated at 91.9% (95% confidence interval: 90.4-93.3%) at nine to 24 months. Adjusting for maternal, child and health system factors, being a member of an association of people living with HIV (adjusted odds ratio: 0.7, 95% CI: 0.1-0.995) improved by 30% HIV-free survival among children, whereas the maternal use of a highly active antiretroviral therapy (HAART) regimen for PMTCT (aOR: 0.6, 95% CI: 0.3-1.07) had a borderline effect.</p> <p>Conclusions</p> <p>HIV-free survival among HIV-exposed children aged nine to 24 months is estimated at 91.9% in Rwanda. The national PMTCT programme could achieve greater impact on child survival by ensuring access to HAART for all HIV-positive pregnant women in need, improving the quality of the programme in rural areas, and strengthening linkages with community-based support systems, including associations of people living with HIV.</p

Under-two child mortality according to maternal HIV status in Rwanda: assessing outcomes within the National PMTCT Program

Introduction: We sought to compare risk of death among children aged under-2 years born to HIV positive mother (HIV-exposed) and to HIV negative mother (HIV non-exposed), and identify determinants of under-2 mortality among the two groups in Rwanda. Methods: In a stratified, two-stage cluster sampling design, we selected mother-child pairs using national Antenatal Care (ANC) registers. Household interview with each mother was conducted to capture socio-demographic data and information related to pregnancy, delivery and post-partum. Data were censored at the date of child death. Using Cox proportional hazard model, we compared the hazard of death among HIV-exposed children and HIV nonexposed children. Results: Of 1,455 HIV-exposed children, 29 (2.0%; 95% CI: 1.3%-2.7%) died by 6 months compared to 18 children of the 1,565 HIV non-exposed children (1.2%; 95% CI: 0.6%-1.7%). By 9 months, cumulative risks of death were 3.0% (95%; CI: 2.2%-3.9%) and 1.3% (96%; CI: 0.7%-1.8%) among HIV-exposed and HIV non-exposed children, respectively. By 2 years, the hazard of death among HIVexposed children was more than 3 times higher (aHR:3.5; 95% CI: 1.8-6.9) among HIV-exposed versus non-exposed children. Risk of death by 9-24 months of age was 50% lower among mothers who attended 4 or more antenatal care (ANC) visits (aHR: 0.5, 95% CI: 0.3-0.9), and 26% lower among families who had more assets (aHR: 0.7, 95% CI: 0.5-1.0). Conclusion: Infant mortality was independent of perinatal HIV exposure among children by 6 months of age. However, HIV-exposed children were 3.5 times more likely to die by 2 years. Fewer antenatal visits, lower household assets and maternal HIV seropositive status were associated with increased mortality by 9-24 months.Key words: HIV, PMTCT, maternal HIV infection, infant mortality, child mortality, under-five mortality, Rwand

PUBLIC KNOWLEDGE, PERCEPTION AND FACTORS ASSOCIATED WITH THE 2009 H1N1 SWINE INFLUENZA VACCINATION : A literature review

The purpose of this study is to analyze public knowledge, perception, and factors associated with the 2009 H1N1 swine influenza vaccination. The aim is to contribute to evidence based practice, so that the results of the study could be used for adopting and implementing strategies against pandemics. Based on search words, twelve articles were selected for the study. The articles came from Pub Med, Google Scholar, other online magazines as well as from Library databases. These articles were analyzed and synthesized for the study results. The results of the study show that the majority of publications perceived the threat of contracting the disease as harmless despite having enough knowledge about the pandemic. Other preventive measures were considered as being more important than the vaccine as its safety was not clear in the consumers’ mind. Future research should concentrate on the use of media and how the public can be provided with sufficient and efficient information regarding their health in general, especially when it comes to pandemics.Tämän opinnäytetyön tarkoitus on analysoida 2009 H1N1-sikainfluenssan rokotteeseen liittyviä kansan keskuudessa vallitsevia tietoja ja käsityksiä. Tutkimuksen tavoitteena on edesauttaa näyttöön perustuvia käytänteitä niin, että tutkimustuloksia voitaisiin käyttää luomaan ja toteuttamaan strategioita taistelussa pandemioita vastaan. Tutkimusta varten valittiin tiettyjen hakusanojen perusteella yhteensä 12 artikkelia. Lähteinä olivat Pub Med, Google Scholar sekä eri verkkojulkaisut ja kirjastojen tietokannat. Artikkelien valinnan jälkeen tehtiin artikkelien analyysi ja synteesi. Tutkimustulokset osoittavat, että valtaosa osallistujista piti tartunnan saamisen riskiä alhaisena, vaikka heillä oli riittävästi tietoa pandemiasta. Muita ennaltaehkäisyn keinoja pidettiin rokotetta tärkeämpinä, koska ihmisillä ei ollut selkeää kuvaa rokotteen turvallisuudesta. Jatkossa tutkimuksen pitäisi keskittyä tiedotusvälineiden käyttöön ja siihen, miten ihmisille voitaisiin taata riittävät ja tehokkaat tiedot koskien heidän terveyttään yleisellä tasolla ja erityisesti silloin, kun kyse on pandemiasta

Malaria prevalence, spatial clustering and risk factors in a low endemic area of Eastern Rwanda: a cross sectional study

Rwanda reported significant reductions in malaria burden following scale up of control intervention from 2005 to 2010. This study sought to; measure malaria prevalence, describe spatial malaria clustering and investigate for malaria risk factors among health-centre-presumed malaria cases and their household members in Eastern Rwanda. A two-stage health centre and household-based survey was conducted in Ruhuha sector, Eastern Rwanda from April to October 2011. At the health centre, data, including malaria diagnosis and individual level malaria risk factors, was collected. At households of these Index cases, a follow-up survey, including malaria screening for all household members and collecting household level malaria risk factor data, was conducted. Malaria prevalence among health centre attendees was 22.8%. At the household level, 90 households (out of 520) had at least one malaria-infected member and the overall malaria prevalence for the 2634 household members screened was 5.1%. Among health centre attendees, the age group 5-15 years was significantly associated with an increased malaria risk and a reported ownership of ≥4 bednets was significantly associated with a reduced malaria risk. At the household level, age groups 5-15 and >15 years and being associated with a malaria positive index case were associated with an increased malaria risk, while an observed ownership of ≥4 bednets was associated with a malaria risk-protective effect. Significant spatial malaria clustering among household cases with clusters located close to water- based agro-ecosystems was observed. Malaria prevalence was significantly higher among health centre attendees and their household members in an area with significant household spatial malaria clustering. Circle surveillance involving passive case finding at health centres and proactive case detection in households can be a powerful tool for identifying household level malaria burden, risk factors and clusterin

Supporting volunteer mentors: Insights from a mentorship program for youth-headed households in Rwanda

In 2004, World Vision Rwanda (WVR), in collaboration with Tulane University and the Rwanda School of Public Health, implemented a program to provide support through regular visits by an adult mentor to youth living without adult care. After completion of baseline quantitative and qualitative research, WVR implemented the program in two areas of a province in southwestern Rwanda. Over an 18-month period, 156 trained adult mentors visited and supported 441 youth-headed households. The mentor training covered key aspects of child development and skills for addressing key psychosocial issues that were identified through the baseline research. Specifically, the training addressed how to engage the youth household heads in discussion and problem-solving, and how to serve as caring and interested adults. Mentors were also trained in how to interact with youth in other ways, such as playing with younger children, providing fun and recreational activities for older youth, and giving praise and encouragement. As noted in this brief, barriers to community support and negative attitudes about orphans uncovered by the baseline research were also addressed in the training

Health facility attendee characteristics and malaria risk factors.

<p>Health facility attendee characteristics and malaria risk factors.</p