510 research outputs found

    Waste Stream and Green Purchasing Analysis at Bonneville Lock and Dam

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    The United States Army Corps of Engineers (USACE), Portland District, has jurisdiction on three locks and four dams in the Columbia River basin. These sites contribute to a water resource management system that provides flood risk management, power generation, water quality improvement, fish and wildlife habitat and recreation on the Columbia River and some of its tributaries . The Bonneville Lock and Dam (Bonneville Project) site lies on the Columbia River approximately 40 miles east from Portland, Oregon. Portions of the site have been declared a National Historic Landmark, from its origins in President Franklin D. Roosevelt\u27s New Deal program from the Public Works Administration project. The spillway, first powerhouse, and navigation lock were completed in 1938 with the second powerhouse completed in 1981 and a larger navigation lock completed in 1993. With its location on the Columbia River, the Bonneville Project also incorporates fish passages that allow Chinook salmon, Steelhead, and other fish species access to their historical habitat in the upper Columbia River Basin. The important location of the Bonneville Project, due to its proximity to Portland, Oregon and being situated on the Columbia River, lends the site to be vigilant of its use of chemicals that could negatively impact the surrounding area and the lower Columbia River. While hazardous waste is thoroughly documented and labeled according to Bonneville Project\u27s Waste Management Program to ensure compliance with 40 CFR Parts 260 through 279 of the Resource Conservation and Recovery Act, characterization and approximate amount produced of non-hazardous waste is not known, and is one of the major focuses of this project. In the October 2016 to September 2017 fiscal year, USACE at Bonneville Project was directed to look into reducing their non-hazardous solid waste by 50%, construction and demolition (C&D) solid waste by 60%, and expand their environmentally preferable purchasing program to increase sustainability. With an emphasis on the Integrated Solid Waste Management program focusing on sustainable acquisition and incorporating a variety of diversion techniques to minimize the landfilling of solid waste, the need to understand the waste characterization and chemical use at Bonneville Project is needed. The characterization of non-hazardous waste is also needed to ensure compliance with USACE environmental compliance assessment program, which is incorporating compliance requirements from USACE Non-Hazardous Solid Waste Diversion and Materials Management Policy. With the added focus on sustainable acquisition and the location of the Bonneville Project on an ecologically important area, considering and potentially incorporating chemical products that are less harmful to the surrounding environment take on an added importance. This project has two main objectives. The first objective of this project is to analyze the waste stream of the Bonneville Project to enable management to look at possible ways to reduce their non-hazardous solid waste by 50% and to establish conformance to USACE Non-Hazardous Solid Waste Diversion and Materials Management Policy. The second objective of this project is to conduct a green purchasing analysis with a focus on chemical products used at the Bonneville Project in order to potentially incorporate chemical products that are less harmful to the environment when used and to reduce the overall chemical count onsite

    Two new Acrididae from the neighbourhood of lake Zaisan (Orthopt.)

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    The following two new Acrididae were taken by me in July and August, 1928 in the valley of the lake Zaisan and in the western part of Saur Mountains.Peer reviewe

    Notes on the Siberian representatives of the genus Acrydium Geoffr. (Orthopt.)

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    During the last five years I have accumulated a small but interesting collection of the Siberian forms of the genus Acrydium Geoffr. (= Tettix Charp.) The collection contains some interesting species and subspecies of this difficult genus; two species and one subspecies are new for science, while some forms are new for Siberia. I am greatly obliged to Mr. B. P. Uvarov for his kind assistance in preparing this paper.Peer reviewe

    2018 Artist in Residence Biennial (Exhibition Catalogue)

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    The presence of acclaimed artists—who have lived and worked in major cultural centers across the country—enhances the educational opportunities for both undergraduate and graduate students enrolled in the University of Tennessee School of Art. With daily contact over the course of a full semester, resident artists develop a unique relationship with the student body which complements the creative stimulation offered by guest lecturers and the School of Art’s faculty. Representing diverse ethnic, cultural, educational, and professional backgrounds, these resident artists introduce another layer of candor and a fresh artistic standard for the students who, though early in their formal art studies, are beginning to develop their own perceptions, skills, and theories in connection with the making of art. 2018 exhibiting Artists were Dana DeGiulio, Ezra Tessler, Clare Grill, and Caitlin Cherry

    2020 Artist In Residence Biennial (Exhibition Catalogue)

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    The presence of acclaimed artists—who have lived and worked in major cultural centers across the country—enhances the educational opportunities for both undergraduate and graduate students enrolled in the University of Tennessee School of Art. With daily contact over the course of a full semester, resident artists develop a unique relationship with the student body which complements the creative stimulation offered by guest lecturers and the School of Art’s faculty. Representing diverse ethnic, cultural, educational, and professional backgrounds, these resident artists introduce another layer of candor and a fresh artistic standard for the students who, though early in their formal art studies, are beginning to develop their own perceptions, skills, and theories in connection with the making of art. The 2020 exhibiting artists were Dana Lok, Fox Hysen, Tracy Thomason, and Caitlin MacBride

    ATR-mediated phosphorylation of DNA polymerase η is needed for efficient recovery from UV damage

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    DNA polymerase η (polη) belongs to the Y-family of DNA polymerases and facilitates translesion synthesis past UV damage. We show that, after UV irradiation, polη becomes phosphorylated at Ser601 by the ataxia-telangiectasia mutated and Rad3-related (ATR) kinase. DNA damage–induced phosphorylation of polη depends on its physical interaction with Rad18 but is independent of PCNA monoubiquitination. It requires the ubiquitin-binding domain of polη but not its PCNA-interacting motif. ATR-dependent phosphorylation of polη is necessary to restore normal survival and postreplication repair after ultraviolet irradiation in xeroderma pigmentosum variant fibroblasts, and is involved in the checkpoint response to UV damage. Taken together, our results provide evidence for a link between DNA damage–induced checkpoint activation and translesion synthesis in mammalian cells

    Les DermaptĂšres du Tibet

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    La faune des DermaptÚres du Tibet restait inconnue dans son ensemble puisqu'il n'existait dans la littérature dermaptérologique que des notes détachées sur peu d'espÚces de ce groupe.Peer reviewe

    Effect of Strontium Ranelate on Femur Densitometry and Antioxidative/Oxidative Status in Castrated Male Rats

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    The studies were aimed at determinatning of the effect of strontium ranelate (SR) on the mineralization  processes and selected parameters of oxidative stress in orchidectomized rats during the development of  osteopenia. Male Wistar rats were sham-operated (SHO) and orchidectomized (ORX). ORX animals were  divided into control (ORX-C) and gavaged with SR (ORX-SR), at a dose of 900mg/kg/b.w. After 60 days  the animals were scanned for determination of bone mineral density (BMD) of the whole skeleton. Isolated  femora were examined by DEXA and pQCT. Tomographic measurements were performed for a total  slice and separately for the cortical and trabecular parts of the distal end of the femora. The intensity of  lipid peroxidation (ILP) and total antioxidant capacity (TAC) in blood serum were measured. SR treatment  increased vBMD and BMC of total, trabecular and cortical bone in ORX rats compared to ORX-C and  SHO rats. ORX significantly increased TAC in control animals, and SR limited this increase. ILP in SHO  and ORX-C rats which on a similar level. SR increased ILP by 21.3%, as compared to SHO. SR improved  densitometric and geometric parameters of femora by orchidectomized rats what prevented degradation of  bone tissue. Beneficial effects of SR were also demonstrated in stabilization of TAC in ORX rats at the level  noted in SHO rats.

    Enhancers dysfunction in the 3D genome of cancer cells

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    Eukaryotic genomes are spatially organized inside the cell nucleus, forming a threedimensional (3D) architecture that allows for spatial separation of nuclear processes and for controlled expression of genes required for cell identity specification and tissue homeostasis. Hence, it is of no surprise that mis-regulation of genome architecture through rearrangements of the linear genome sequence or epigenetic perturbations are often linked to aberrant gene expression programs in tumor cells. Increasing research efforts have shed light into the causes and consequences of alterations of 3D genome organization. In this review, we summarize the current knowledge on how 3D genome architecture is dysregulated in cancer, with a focus on enhancer highjacking events and their contribution to tumorigenesis. Studying the functional effects of genome architecture perturbations on gene expression in cancer offers a unique opportunity for a deeper understanding of tumor biology and sets the basis for the discovery of novel therapeutic targets
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