69 research outputs found
Bibliotheken im Buch: Die Erschließung von privaten Büchersammlungen der Frühneuzeit über Auktionskataloge
Der Beitrag demonstriert anhand eines Auktionskatalogs von 1670 unser Vorgehen, frühneuzeitliche Gelehrtenbibliotheken bibliographisch nachhaltig zu erschließen. In einem ersten Schritt beschreiben wir die Erfassung der im Katalog verzeichneten Titel. Das Instrument für diesen Arbeitsgang ist eine Excel-Tabelle, die bibliographische Ermittlung erfolgt mit Hilfe nationaler und internationaler Online-Kataloge. Im zweiten Schritt geht es um die Entwicklung der digitalen Infrastruktur für die Onlinepräsentation der Daten. Hierzu wurde ein frei nachnutzbares Programm entwickelt, das für die Rekonstruktion frühneuzeitlicher Privatbibliotheken optimiert ist. Vorgestellt werden die verschiedenen textlichen und graphischen Visualisierungsformen sowie die weitergehenden Einsatzmöglichkeiten als Darstellungs- und Normierungstool für bibliographische Daten. Im dritten Schritt skizzieren wir den absolvierten Workflow und zeigen, wie traditionelle Methoden der Altbestandserschließung mit Verfahren der Digital Humanities kombiniert werden können. Dabei rückt auch die digitale Edition eines Briefwechsels in den Blick, der den Auktionskatalog als Sekundärquelle flankiert
Magnetic microcalorimeters for primary activity standardization within the EMPIR project PrimA-LTD
The precision of existing decay data of radionuclides for activity
determination is often a limitation for actual applications in science,
society, and industry. For this reason, the EMPIR project PrimA-LTD aims to
introduce an advanced primary activity standardization technique that is based
on magnetic microcalorimeters (MMCs) and that will offer very low energy
threshold of few eV and a decay scheme independent detection efficiency close
to 100%. As a proof of concept, we developed two MMC-based detector types in
order to standardize an -decaying, a -decaying and an electron
capture decaying isotope. One detector type aims to introduce a reusable
detector setup, while the other aims to provide highly accurate decay spectra
by high resolution measurements with high statistics. We present the designs,
fabrication status and first characterization measurements of both detectors
types and outline next steps.Comment: This manuscript was submitted to the Journal of Low Temperature
Physics as part of the special issue "LTD20", supporting the conference
contribution TP-06
Magnetic Microcalorimeters for Primary Activity Standardization Within the EMPIR Project PrimA-LTD
The precision of existing decay data of radionuclides for activity determination is often a limitation for actual applications in science, society and industry. For this reason, the EMPIR project PrimA-LTD aims to introduce an advanced primary activity standardization technique that is based on magnetic microcalorimeters (MMCs) and that will offer very low energy threshold of few eV and a decay scheme-independent detection efficiency close to 100 %. As a proof of concept, we developed two MMC-based detector types in order to standardize an -decaying, a -decaying and an electron capture decaying isotope. One detector type aims to introduce a reusable detector setup, while the other aims to provide highly accurate decay spectra by high-resolution measurements with high statistics. We present the designs, fabrication status and first characterization measurements of both detectors types and outline next steps
Photoscanning-Methode zur nichtinvasiven Charakterisierung fabrikationsbedingter Defekte in Solarzellen
Im folgenden Beitrag wird ein Verfahren zur nichtinvasiven Charakterisierung fabrikationsbedingter Defekte in Solarzellen, wie beispielsweise unterbrochene Fingerkontakte oder Risse im Solarmaterial, vorgestellt. Es werden Weiterentwicklungsansätze aufgezeigt, die zum Ziel haben, das Verfahren auf die einfache und schnelle Erkennbarkeit von Rissen zu optimieren, und es werden erste Untersuchungsergebnisse präsentiert
Bell violation with entangled photons, free of the fair-sampling assumption
The violation of a Bell inequality is an experimental observation that forces
one to abandon a local realistic worldview, namely, one in which physical
properties are (probabilistically) defined prior to and independent of
measurement and no physical influence can propagate faster than the speed of
light. All such experimental violations require additional assumptions
depending on their specific construction making them vulnerable to so-called
"loopholes." Here, we use photons and high-efficiency superconducting detectors
to violate a Bell inequality closing the fair-sampling loophole, i.e. without
assuming that the sample of measured photons accurately represents the entire
ensemble. Additionally, we demonstrate that our setup can realize one-sided
device-independent quantum key distribution on both sides. This represents a
significant advance relevant to both fundamental tests and promising quantum
applications
Inflammation of the rectal remnant endangers the outcome of ileal pouch-anal anastomosis: a case–control study
Background: Inflammation of the rectal remnant may affect the postoperative outcome of ileal pouch-anal anastomosis (IPAA) in patients with ulcerative colitis (UC). We aimed to determine the extent of inflammation in the anastomotic area during IPAA and to investigate the impact of proctitis on postoperative complications and long-term outcomes.
Methods: Three hundred thirty-four UC patients with primary IPAA were included in this retrospective case-control study. The histopathologic degree of inflammation in the anastomotic area was graded into three stages of no proctitis ("NOP"), mild to medium proctitis ("MIP"), and severe proctitis ("SEP"). Preoperative risk factors, 30-day morbidity, and follow-up data were assessed. Kaplan-Meier analysis was performed in the event of pouch failure.
Results: The prevalence of proctitis was high (MIP 40.4%, and SEP 42.8%). During follow-up, the incidence of complications was highest among SEP: resulting in re-intervention (n = 40; 28.2%, p = 0.017), pouchitis (n = 36; 25.2%, p < 0.01), and pouch failure (n = 32; 22.4%, p = 0.032). The time interval to pouch failure was 5.0 (4.0-6.9) years among NOP, and 1.2 (0.5-2.3) years in SEP (p = 0.036). ASA 3, pouchitis, and pouch fistula were independent risk factors for pouch failure.
Conclusion: Proctitis at the time of IPAA is common. A high degree of inflammation is associated with poor long-term outcomes, an effect that declines over time. In addition, a higher degree of proctitis leads to earlier pouch failure
Exploring the photon-number distribution of bimodal microlasers with a transition edge sensor
The research leading to these results has received funding from the European Research Council under the European Union's Seventh Framework ERC Grant Agreement No. 615613, within the EURAMET joint research project MIQC2 from the European Union's Horizon 2020 Research and Innovation Programme and the EMPIR Participating States and from the German Research Foundation within the project RE2974/10-1. The authors thank the State of Bavaria for financial support.A photon-number resolving transition edge sensor (TES) is used to measure the photon-number distribution of two microcavity lasers. The investigated devices are bimodal microlasers with similar emission intensity and photon statistics with respect to the photon auto-correlation. Both high-β microlasers show partly thermal and partly coherent emission around the lasing threshold. For higher pump powers, the strong mode of microlaser { A } emits Poissonian distributed photons while the emission of the weak mode is thermal. In contrast, laser { B } shows a bistability resulting in overlayed thermal and Poissonian distributions. While a standard Hanbury Brown and Twiss experiment cannot distinguish between simple thermal emission of laser { A } and the temporal mode switching of the bistable laser { B }, TESs allow us to measure the photon-number distribution which provides important insight into the underlying emission processes. Indeed, our experimental data and its theoretical description by a master equation approach show that TESs are capable of revealing subtle effects like mode switching of bimodal microlasers. As such our studies clearly demonstrate the benefit and importance of investigating nanophotonic devices via photon-number resolving transition edge sensors.PostprintPeer reviewe
Thermal effects in dissimilar magnetic pulse welding
Magnetic pulse welding (MPW) is often categorized as a cold welding technology, whereas latest studies evidence melted and rapidly cooled regions within the joining interface. These phenomena already occur at very low impact velocities, when the heat input due to plastic deformation is comparatively low and where jetting in the kind of a distinct material flow is not initiated. As another heat source, this study investigates the cloud of particles (CoP), which is ejected as a result of the high speed impact. MPW experiments with different collision conditions are carried out in vacuum to suppress the interaction with the surrounding air for an improved process monitoring. Long time exposures and flash measurements indicate a higher temperature in the joining gap for smaller collision angles. Furthermore, the CoP becomes a finely dispersed metal vapor because of the higher degree of compression and the increased temperature. These conditions are beneficial for the surface activation of both joining partners. A numerical temperature model based on the theory of liquid state bonding is developed and considers the heating due to the CoP as well as the enthalpy of fusion and crystallization, respectively. The time offset between the heat input and the contact is identified as an important factor for a successful weld formation. Low values are beneficial to ensure high surface temperatures at the time of contact, which corresponds to the experimental results at small collision angle
Tailoring the mode-switching dynamics in quantum-dot micropillar lasers via time-delayed optical feedback
Funding: European Research Council under the European Union’s Seventh Framework Program (ERC Grant Agreement No. 615613); German Research Foundation (CRC 787, GRK1558); project EMPIR 14IND05 MIQC2 co-financed by the Participating States and from the European Union’s Horizon 2020 research and innovation program.Microlasers are ideal candidates to bring the fascinating variety of nonlinear complex dynamics found in delay-coupled systems to the realm of quantum optics. Particularly attractive is the possibility of tailoring the devices’ emission properties via non-invasive delayed optical coupling. However, until now scarce research has been done in this direction. Here, we experimentally and theoretically investigate the effects of delayed optical feedback on the mode-switching dynamics of an electrically driven bimodal quantum-dot micropillar laser, characterizing its impact on the micropillar’s output power, optical spectrum and photon statistics. Feedback is found to influence the switching dynamics and its characteristics time scales. In addition, stochastic switching is reduced with the subsequent impact on the microlaser photon statistics. Our results contribute to the comprehension of feedback-induced phenomena in micropillar lasers and pave the way towards the external control and tailoring of the properties of these key systems for the nanophotonics community.Publisher PDFPeer reviewe
Metastatic Potential of Small Testicular Germ Cell Tumors: Implications for Surveillance of Small Testicular Masses.
Incidental detection of urogenital tumors has increased in recent decades owing to the greater use of ultrasonography and cross-sectional imaging. For patients with low-risk prostate cancer or small renal masses, active surveillance represents a valid treatment option. Similarly, for men with small testicular masses <10 mm, active surveillance has been discussed as an alternative to surgery, although little is known regarding the behavior of small testicular germ cell tumors (GCTs). In the Swiss Austrian German Testicular Cancer Cohort Study we identified 849 patients (546 seminoma, 303 nonseminoma) treated with radical inguinal orchiectomy for GCT with a median tumor diameter of 35 mm. A tumor diameter <10 mm was observed in 25 patients (13 seminoma, 12 nonseminoma). Of these, five patients (20%) presented with primary metastatic disease, all of whom had elevated tumor markers and nonseminomatous GCTs. Two patients (8%) with initially localized disease (1 seminoma, 1 nonseminoma) and without elevated tumor markers experienced relapse at 4 mo (nonseminoma) and 14 mo (seminoma) after orchiectomy, despite the fact that the latter had received adjuvant chemotherapy. These findings highlight the metastatic potential of small testicular GCTs and raise the question of whether active surveillance for small testicular masses is safe.
Patient summary
This study on testicular cancer assesses the metastatic potential of small testicular germ cell tumors. Men with small testicular masses should be counseled about the malignant potential of small testicular germ cell tumors
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