669 research outputs found

    Legal Indenture John Bergen to Peter Kean, March 18, 1811

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    Legal Indenture from John Bergen of South Brunswick, NJ to Peter Kean for $391 for the sale of three enslaved people, Cirus, Peggy, and Peggy\u27s infant Elias. Peter would hold Cirus for eight years. Writing on the back indicates that Elias is Cyrus\u27s son and that Peter purchased them for Susan Ursin Niemcewicz, his mother. Enslaved People Included: Cirus or Cyrus, Peggy, Elias People Included: Susan Ursin Niemcewiczhttps://digitalcommons.kean.edu/lhc_1810s/1006/thumbnail.jp

    Illegal immigration and worldview defense: Distaste for human migration in the context of TMT

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    This study examines the impact of mortality salience on opinions about illegal immigrants. Participants were asked to write about their own death or a control subject and then presented with scenarios of illegal immigration to the United States. The scenarios included a defendant who was either of Latin American or European origin and had or had not learned to speak English. However, the European condition had to be dropped due to unreliable identification of the origin of the European defendant. The results indicate that mortality salience caused an increase in the preference for deportation of an illegal immigrant who was perceived to have had a high level of contribution to the economy

    Prospectives

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    Tiré de: Prospectives, vol. 24, no 2, avril 1988.Titre de l'écran-titre (visionné le 24 janv. 2013

    Gender role conflict and coping : a preliminary investigation of college males

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    This study investigated differences in coping strategies between college males with high and low gender role conflict, as measured by the Gender Role Conflict Scale (GRCS). Emotion-focused and problem-focused coping strategies of men, as assessed by the Ways of Coping Questionnaire (WOCQ), also were examined across gender role conflict-specific and gender role conflict-neutral stressful encounters. Traditional age college males living on-campus at two small private colleges located in southeastern United States completed the GRCS, the WOCQ and a demographic questionnaire. Responses were received from 247 students. Comparisons were completed to examine the coping profiles between men with high and low gender role conflict. Selection of coping strategies was investigated to compare high and low gender role conflict men in response to scenarios characterized by high and low gender role conflict. Coping profiles were not found to differ significantly in either analysis. Examination between the factors of the GRCS and subscales of the WOCQ revealed no direct significant relationships

    What drives quality physical education? : a systematic review and meta-analysis of learning and development effects from physical education-based interventions

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    Objective: To determine the effects of learning interventions aimed at optimizing the quality of physical education (PE) on psychomotor, cognitive, affective and social learning outcomes in children and adolescents. Design: A systematic review and meta-analysis. Data Sources: After searching PsycInfo, ERIC, and SportDiscus electronic databases, we identified 135 eligible studies published between January 1, 1995 to May 1, 2021. Eligibility Criteria for Selecting Studies: We included randomized controlled trials, quasi-experimental studies, and controlled trials that assessed the effect of a PE-based intervention against one of the four identified learning domains in youth at school (aged 5-18 years). Results: One hundred and thirty five (135) studies with over 42,500 participants and 193 calculated effect sizes were included in the study. The mean effect across all the learning and development outcomes was small to medium (Cohen's d = 0.32, 95% confidence interval [CI] (0.27-0.37). When adjusted for publication bias using the Duval and Tweedie Trim and Fill Method, this mean effect size increased to d = 0.40 (CI = 0.34-0.46). Effect sizes varied significantly based on learning and development outcomes. Interventions that consistently report above or below the mean d = 0.40 effect are identified based on learning outcome. The greatest effects across interventions were witnessed in psychomotor learning outcomes (d = 0.52) followed by affective (d = 0.47), social (d = 0.32), and cognitive (d = 0.17) learning outcomes. A minority (< 10%) of PE interventions captured by this systematic review and meta-analysis reported having a negative effect on student learning and development. Conclusion: The interventions with the greatest effects on student learning and development were dependant on the learning domains. Some PE interventions with a pedagogical focus such as games-based approaches, TARGET/Mastery Teaching, and Sport Education were found to be strong investments across multiple domains. The evidence is limited however by consistency in intervention dosage, study design, and data collection instruments. The study received no internal or external funding and was not prospectively registered

    Comparison of the Immune Responses Induced by Chimeric Alphavirus-Vectored and Formalin-Inactivated Alum-Precipitated Measles Vaccines in Mice

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    A variety of vaccine platforms are under study for development of new vaccines for measles. Problems with past measles vaccines are incompletely understood and underscore the need to understand the types of immune responses induced by different types of vaccines. Detailed immune response evaluation is most easily performed in mice. Although mice are not susceptible to infection with wild type or vaccine strains of measles virus, they can be used for comparative evaluation of the immune responses to measles vaccines of other types. In this study we compared the immune responses in mice to a new protective alphavirus replicon particle vaccine expressing the measles virus hemagglutinin (VEE/SIN-H) with a non-protective formalin-inactivated, alum-precipitated measles vaccine (FI-MV). MV-specific IgG levels were similar, but VEE/SIN-H antibody was high avidity IgG2a with neutralizing activity while FI-MV antibody was low-avidity IgG1 without neutralizing activity. FI-MV antibody was primarily against the nucleoprotein with no priming to H. Germinal centers appeared, peaked and resolved later for FI-MV. Lymph node MV antibody-secreting cells were more numerous after FI-MV than VEE/SIN-H, but were similar in the bone marrow. VEE/SIN-H-induced T cells produced IFN-γ and IL-4 both spontaneously ex vivo and after stimulation, while FI-MV-induced T cells produced IL-4 only after stimulation. In summary, VEE/SIN-H induced a balanced T cell response and high avidity neutralizing IgG2a while FI-MV induced a type 2 T cell response, abundant plasmablasts, late germinal centers and low avidity non-neutralizing IgG1 against the nucleoprotein

    Phosphatidylserine stimulates ceramide 1-phosphate (C1P) intermembrane transfer by C1P transfer proteins

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    Genetic models for studying localized cell suicide that halt the spread of pathogen infection and immune response activation in plants include Arabidopsis accelerated-cell-death 11 mutant (acd11). In this mutant, sphingolipid homeostasis is disrupted via depletion of ACD11, a lipid transfer protein that is specific for ceramide 1-phosphate (C1P) and phyto-C1P. The C1P binding site in ACD11 and in human ceramide-1-phosphate transfer protein (CPTP) is surrounded by cationic residues. Here, we investigated the functional regulation of ACD11 and CPTP by anionic phosphoglycerides and found that 1-palmitoyl-2-oleoyl-phosphatidic acid or 1-palmitoyl-2-oleoyl-phosphatidylglycerol (≤15 mol %) in C1P source vesicles depressed C1P intermembrane transfer. By contrast, replacement with 1-palmitoyl-2-oleoyl-phosphatidylserine stimulated C1P transfer by ACD11 and CPTP. Notably, “soluble” phosphatidylserine (dihexanoyl-phosphatidylserine) failed to stimulate C1P transfer. Also, none of the anionic phosphoglycerides affected transfer action by human glycolipid lipid transfer protein (GLTP), which is glycolipid-specific and has few cationic residues near its glycolipid binding site. These findings provide the first evidence for a potential phosphoglyceride headgroup-specific regulatory interaction site(s) existing on the surface of any GLTP-fold and delineate new differences between GLTP superfamily members that are specific for C1P versus glycolipid
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