3 research outputs found

    The Strategy of Ukrainian migrants in the labor market of the Czech Republic

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    Ve své bakalářské práci se zabývám problematikou života ukrajinských pracovních migrantů na českém trhu práce. Mým hlavním cílem bylo identifikovat "strategie přežití", které si migranti utvářejí v rámci každodenního života na české trhu práce. V práci je použita kvalitativní metodologie sociologického výzkumu. V praktické části této práce se v rámci tématické analýzy snažím identifikovat klíčové faktory, které ovlivňují život a existenci těchto pracovních migrantů na zdejším trhu práce.Katedra sociologieObhájenoIn my bachelor's thesis I focus on the life of Ukrainian labor migrants on the Czech labor market. My main goal was to identify the "survival strategy" by the migrants make up the everyday life of the Czech labor market. The authors used qualitative methodology of sociological research. In the practical part of this work under the thematic analysis trying to identify the key factors that affect the life and existence of migrant workers in the local labor market

    Case Study reclamation of the quarry Silvestr in the Sokolov, or the path from the quarry to golf

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    This diploma thesis deals with the issue of public participation in deciding activities of reclamation. I chose former quarry Silvester near Dolni Rychnov as my research area. This area was transformed into eighteen-holes golf grounds and wood grounds with sport and relax stuff during reclamation work. This thesis consist of theoretical, methodological and empirical section. Theoretical section introduce basic concept of recultivation, law regulating recultivation, conservation, restoration ecology as scientic field and last but not least Sokolov region as region with long tradition of recultivation. The Methodological part describes methods of practical research, which is essential part of this thesis. The Empirical section introduce results of my research. Key words: reclamation, opencast coal-mining, restauration ekology, nature conservation, reclamation project, expert interview, questionnair

    Quercetin Improves Postischemic Recovery of Heart Function in Doxorubicin-Treated Rats and Prevents Doxorubicin-Induced Matrix Metalloproteinase-2 Activation and Apoptosis Induction

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    Quercetin (QCT) is flavonoid that possesses various biological functions including anti-oxidative and radical-scavenging activities. Moreover, QCT exerts some preventive actions in treatment of cardiovascular diseases. The aim of present study was to explore effects of prolonged administration of QCT on changes induced by repeated application of doxorubicin (DOX) in rat hearts. We focused on the ultrastructure of myocardium, matrix metalloproteinases (MMPs), biometric parameters, and apoptosis induction. Our aim was also to examine effects of QCT on ischemic tolerance in hearts exposed to chronic effects of DOX, and to determine possible mechanisms underlying effects of QCT. Our results showed that QCT prevented several negative chronic effects of DOX: (I) reversed DOX-induced blood pressure increase; (II) mediated improvement of deleterious effects of DOX on ultrastructure of left ventricle; (III) prevented DOX-induced effects on tissue MMP-2 activation; and (iv) reversed effects of DOX on apoptosis induction and superoxide dismutase inhibition. Moreover, we showed that rat hearts exposed to effects of QCT were more resistant to ischemia/reperfusion injury. Effects of QCT on modulation of ischemic tolerance were linked to Akt kinase activation and connexin-43 up-regulation. Taken together, these results demonstrate that prolonged treatment with QCT prevented negative chronic effects of DOX on blood pressure, cellular damage, MMP-2 activation, and apoptosis induction. Moreover, QCT influenced myocardial responses to acute ischemic stress. These facts bring new insights into mechanisms of QCT action on rat hearts exposed to the chronic effects of DOX
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