Impact of high-frequency pumping on anomalous finite-size effects in three-dimensional topological insulators

Lowering of the thickness of a thin-film three-dimensional topological insulator down to a few nanometers results in the gap opening in the spectrum of topologically protected two-dimensional surface states. This phenomenon, which is referred to as the anomalous finite-size effect, originates from hybridization between the states propagating along the opposite boundaries. In this work, we consider a bismuth-based topological insulator and show how the coupling to an intense high-frequency linearly polarized pumping can further be used to manipulate the value of a gap. We address this effect within recently proposed Brillouin-Wigner perturbation theory that allows us to map a time-dependent problem into a stationary one. Our analysis reveals that both the gap and the components of the group velocity of the surface states can be tuned in a controllable fashion by adjusting the intensity of the driving field within an experimentally accessible range and demonstrate the effect of light-induced band inversion in the spectrum of the surface states for high enough values of the pump.Comment: 6 pages, 3 figure

Isospin dependence of nucleon effective mass in Dirac Brueckner-Hartree-Fock approach

The isospin dependence of the nucleon effective mass is investigated in the framework of the Dirac Brueckner-Hartree-Fock (DBHF) approach. The definition of nucleon scalar and vector effective masses in the relativistic approach is clarified. Only the vector effective mass is the quantity related to the empirical value extracted from the analysis in the nonrelatiistic shell and optical potentials. In the relativistic mean field theory, where the nucleon scalar and vector potentials are both energy independent, the neutron vector potential is stronger than that of proton in the neutron rich nuclear matter, which produces a smaller neutron vector effective mass than that of proton. It is pointed out that the energy dependence of nucleon potentials has to be considered in the analysis of the isospin dependence of the nucleon effective mass. In the DBHF the neutron vector effective mass is larger than that of proton once the energy dependence of nucleon potentials is considered. The results are consistent with the analysis of phenomenological isospin dependent optical potentials.Comment: 4 pages, 3 Postscript figure

Observation of Full-Parameter Jones Matrix in Bilayer Metasurface

Metasurfaces, artificial 2D structures, have been widely used for the design of various functionalities in optics. Jones matrix, a 2*2 matrix with eight parameters, provides the most complete characterization of the metasurface structures in linear optics, and the number of free parameters (i.e., degrees of freedom, DOFs) in the Jones matrix determines the limit to what functionalities we can realize. Great efforts have been made to continuously expand the number of DOFs, and a maximal number of six has been achieved recently. However, the realization of 'holy grail' goal with eight DOFs (full free parameters) has been proven as a great challenge so far. Here, we show that by cascading two layer metasurfaces and utilizing the gradient descent optimization algorithm, a spatially varying Jones matrix with eight DOFs is constructed and verified numerically and experimentally in optical frequencies. Such ultimate control unlocks new opportunities to design optical functionalities that are unattainable with previously known methodologies and may find wide potential applications in optical fields.Comment: 53 paegs, 4 figure

Inhibition of SREBP by a Small Molecule, Betulin, Improves Hyperlipidemia and Insulin Resistance and Reduces Atherosclerotic Plaques

SummarySterol regulatory element-binding proteins (SREBPs) are major transcription factors activating the expression of genes involved in biosynthesis of cholesterol, fatty acid and triglyceride. In this study, we identified a small molecule, betulin, that specifically inhibited the maturation of SREBP by inducing interaction of SREBP cleavage activating protein (SCAP) and Insig. Inhibition of SREBP by betulin decreased the biosynthesis of cholesterol and fatty acid. In vivo, betulin ameliorated diet-induced obesity, decreased the lipid contents in serum and tissues, and increased insulin sensitivity. Furthermore, betulin reduced the size and improved the stability of atherosclerotic plaques. Our study demonstrates that inhibition SREBP pathway can be employed as a therapeutic strategy to treat metabolic diseases including type II diabetes and atherosclerosis. Betulin, which is abundant in birch bark, could be a leading compound for development of drugs for hyperlipidemia

Elevation of Inducible Nitric Oxide Synthase and Cyclooxygenase-2 Expression in the Mouse Brain after Chronic Nonylphenol Exposure

The present study was performed to investigate the effects of chronic administration of nonylphenol (NP) on the expression of inflammation-related genes in the brains of mice. NP was given orally by gavages at 0, 50, 100, and 200 mg/kg/d. The expression of inflammatory enzymes, inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2), was evaluated by immunohistochemistry and immunoblotting assays. The nitric oxide (NO) level and nitric oxide synthase (NOS) activity were also measured by biochemical analyses. The results showed that NP at a high dose (200 mg/kg/d) significantly increased the expression of iNOS and COX-2 in both the hippocampus and cortex. In parallel with the increase in iNOS expression, the NO level was significantly greater at the dose of 200 mg/kg/d, compared to the control. The activity of NOS was also increased in the brain of mice at the dose of 100 and 200 mg/kg/d. These findings demonstrate that NP may have the potential to induce the chronic inflammation or cause neurotoxicity in the mouse brain

Slow cooling and efficient extraction of C-exciton hot carriers in MoS2 monolayer

In emerging optoelectronic applications, such as water photolysis, exciton fission and novel photovoltaics involving low-dimensional nanomaterials, hot-carrier relaxation and extraction mechanisms play an indispensable and intriguing role in their photo-electron conversion processes. Two-dimensional transition metal dichalcogenides have attracted much attention in above fields recently; however, insight into the relaxation mechanism of hot electron-hole pairs in the band nesting region denoted as C-excitons, remains elusive. Using MoS2 monolayers as a model two-dimensional transition metal dichalcogenide system, here we report a slower hot-carrier cooling for C-excitons, in comparison with band-edge excitons. We deduce that this effect arises from the favourable band alignment and transient excited-state Coulomb environment, rather than solely on quantum confinement in two-dimension systems. We identify the screening-sensitive bandgap renormalization for MoS2 monolayer/graphene heterostructures, and confirm the initial hot-carrier extraction for the C-exciton state with an unprecedented efficiency of 80%, accompanied by a twofold reduction in the exciton binding energy

DocAsRef: An Empirical Study on Repurposing Reference-Based Summary Quality Metrics Reference-Freely

Automated summary quality assessment falls into two categories: reference-based and reference-free. Reference-based metrics, historically deemed more accurate due to the additional information provided by human-written references, are limited by their reliance on human input. In this paper, we hypothesize that the comparison methodologies used by some reference-based metrics to evaluate a system summary against its corresponding reference can be effectively adapted to assess it against its source document, thereby transforming these metrics into reference-free ones. Experimental results support this hypothesis. After being repurposed reference-freely, the zero-shot BERTScore using the pretrained DeBERTa-large-MNLI model of <0.5B parameters consistently outperforms its original reference-based version across various aspects on the SummEval and Newsroom datasets. It also excels in comparison to most existing reference-free metrics and closely competes with zero-shot summary evaluators based on GPT-3.5.Comment: Accepted into Findings of EMNLP 202