2,088 research outputs found

    Change in high-risk behaviors during the first college year categorized by gender, first-generation status, and admission index demographics as measured by the CIRP and YFCY

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    Title from PDF of title page (University of Missouri--Columbia, viewed on Feb 26, 2010).The entire thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file; a non-technical public abstract appears in the public.pdf file.Dissertation advisor: Dr. Phillip Messner.Vita.Ed. D. University of Missouri--Columbia 2009.The purpose of this case study was to evaluate change in five high-risk behaviors among three demographic groups of first-year college students. The study utilized the CIRP and YFCY surveys to gain pre- and post-measurements of behavior for smoking cigarettes, drinking beer, drinking wine or liquor, feeling depressed, and feeling overwhelmed. This quantitative study measured the change in high-risk behaviors in one cohort of students at a moderately selective Midwestern, four-year public, Masters I University using previously collected, archival data. The independent variables were gender, first-generation status, and admission index. Data were analyzed using the following statistical analysis procedures: descriptive statistic analysis, independent t-tests, multivariate analysis of variance, and discriminant function analysis. Descriptive statistics were used to determine change in high-risk behavior from the beginning of the fall semester (CIRP) to the end of the first year (YFCY). All high-risk behaviors increased during the first-year of college for all independent variables. Independent t-Tests were utilized to evaluate significances among independent variables. A MANOVA was used to evaluate variance among and between independent variables. Significant differences were noted for several combinations of independent variables and high-risk behaviors. However, the measures of power and variance indicated low practicability of data. The discriminant analysis predicted membership using cigarette smoking as the high-risk variable. While the statistical significance was low, important realizations were noted. This research indicates that high-risk behaviors do increase during the first year of college for most students. However, these behaviors were present during the final year of high school. This understanding changes the dialogue of administrators who are charged with designing programs and services to acculturate students to campus life. It is not practical to prevent high-risk behaviors during the first year of college, rather the dialogue consider impacting previously existing behaviors.Includes bibliographical references

    Discrimination of prostate cancer cells and non-malignant cells using secondary ion mass spectrometry

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    This communication utilises Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS) combined with multivariate analysis to obtain spectra from the surfaces of three closely related cell lines allowing their discrimination based upon mass spectral ions

    Deubiquitylating enzymes and disease

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    Deubiquitylating enzymes (DUBs) can hydrolyze a peptide, amide, ester or thiolester bond at the C-terminus of UBIQ (ubiquitin), including the post-translationally formed branched peptide bonds in mono- or multi-ubiquitylated conjugates. DUBs thus have the potential to regulate any UBIQ-mediated cellular process, the two best characterized being proteolysis and protein trafficking. Mammals contain some 80–90 DUBs in five different subfamilies, only a handful of which have been characterized with respect to the proteins that they interact with and deubiquitylate. Several other DUBs have been implicated in various disease processes in which they are changed by mutation, have altered expression levels, and/or form part of regulatory complexes. Specific examples of DUB involvement in various diseases are presented. While no specific drugs targeting DUBs have yet been described, sufficient functional and structural information has accumulated in some cases to allow their rapid development

    Treatment of estrogen-induced dermatitis with omalizumab

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    In 1945, Drs Bernhard Zondek and Yehuda Bromberg demonstrated intradermal treatment with estrone and estradiol benzoate induced urticarial lesions in some patients.1 Fifty years later, Shelley et al,2 who introduced the concept of progesterone dermatitis several decades prior, defined estrogen dermatitis based on studies of 7 women with premenstrual flares of skin eruptions including papulovesicular, urticarial, or eczematous lesions or generalized pruritus. Previously described therapies for estrogen dermatitis include estrogen desensitization, tamoxifen, leuprolide, and oophorectomy.3 Here we report a case of estrogen-induced dermatitis successfully treated with omalizumab

    Technology Criticism for Technophiles

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    Matthew Baker is a recent graduate of the Simmons Graduate School of Library and Information Science. Here he makes the case for librarians to recognize both the strengths and limitations of technology, and to guide students toward that recognition as well

    Generalised Elliptic Functions

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    We consider multiply periodic functions, sometimes called Abelian functions, defined with respect to the period matrices associated with classes of algebraic curves. We realise them as generalisations of the Weierstras P-function using two different approaches. These functions arise naturally as solutions to some of the important equations of mathematical physics and their differential equations, addition formulae, and applications have all been recent topics of study. The first approach discussed sees the functions defined as logarithmic derivatives of the sigma-function, a modified Riemann theta-function. We can make use of known properties of the sigma function to derive power series expansions and in turn the properties mentioned above. This approach has been extended to a wide range of non hyperelliptic and higher genus curves and an overview of recent results is given. The second approach defines the functions algebraically, after first modifying the curve into its equivariant form. This approach allows the use of representation theory to derive a range of results at lower computational cost. We discuss the development of this theory for hyperelliptic curves and how it may be extended in the future.Comment: 16 page
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