Substrate Specificity of Peptide Adsorption: A Model Study

Applying the contact density chain-growth algorithm to lattice heteropolymers, we identify the conformational transitions of a nongrafted hydrophobic-polar heteropolymer with 103 residues in the vicinity of a polar, a hydrophobic, and a uniformly attractive substrate. Introducing only two system parameters, the numbers of surface contacts and intrinsic hydrophobic contacts, respectively, we obtain surprisingly complex temperature and solvent dependent, substrate-specific pseudo-phase diagrams.Comment: 5 pages, 2 figure

Study of ion feedback in multi-GEM structures

We study the feedback of positive ions in triple and quadruple Gas Electron Multiplier (GEM) detectors. The effects of GEM hole diameter, detector gain, applied voltages, number of GEMs and other parameters on ion feedback are investigated in detail. In particular, it was found that the ion feedback is independent of the gas mixture and the pressure. In the optimized multi-GEM structure, the ion feedback current can be suppressed down to 0.5% of the anode current, at a drift field of 0.1 kV/cm and gain of 10^4. A simple model of ion feedback in multi-GEM structures is suggested. The results obtained are relevant to the performance of time projection chambers and gas photomultipliers.Comment: 9 pages, 11 figures. Submitted to Nucl. Instr. and Meth.

Paediatric utilisation of a teaching hospital and a community health centre

No Abstract

Development of a triple GEM UV-photon detector operated in pure CF4 for the PHENIX experiment

Results obtained with a triple GEM detector operated in pure CF4 with and without a reflective CsI photocathode are presented. The detector operates in a stable mode at gains up to 10^4. A deviation from exponential growth starts to develop when the total charge exceeds ~ 4 10^6 e leading to gain saturation when the total charge is ~ 2 10^7 e and making the structure relatively robust against discharges. No aging effects are observed in the GEM foils after a total accumulated charge of ~ 10 mC/cm^2 at the anode. The ion back-flow current to the reflective photocathode is comparable to the electron current to the anode. However, no significant degradation of the CsI photocathode is observed for a total ion back-flow charge of ~ 7 mC/cm^2.Comment: 14 pages, 11 figures, Submitted to NIM

Mid-infrared sub-wavelength grating mirror design: tolerance and influence of technological constraints

High polarization selective Si/SiO2 mid-infrared sub-wavelength grating mirrors with large bandwidth adapted to VCSEL integration are compared. These mirrors have been automatically designed for operation at \lambda = 2.3 $\mu$m by an optimization algorithm which maximizes a specially defined quality factor. Several technological constraints in relation with the grating manufacturing process have been imposed within the optimization algorithm and their impact on the optical properties of the mirror have been evaluated. Furthermore, through the tolerance computation of the different dimensions of the structure, the robustness with respect to fabrication errors has been tested. Finally, it appears that the increase of the optical performances of the mirror imposes a less tolerant design with severer technological constraints resulting in a more stringent control of the manufacturing process.Comment: The final publication is available at http://iopscience.iop.org/2040-8986/13/12/125502

Light multi-GEM detector for high-resolution tracking systems

Controlled etching of copper electrodes in Gas Electron Multiplier foils allows a reduction of the material budget by more than a factor of two for a triple-GEM detector. Detectors making use of thinned foils provide performances similar to those obtained with standard devices: a gain above 10^4 for a double-GEM, with energy resolution of 27 % fwhm for 5.9 keV X-rays.Comment: Submitted to Nucl.Instr.& Meth.