Inhibition Effect of 6-bromo-3-nitro-2-phenylimidazol[1,2-α] pyridine on the Corrosion of C38 Steel in H2SO4 Solution

The inhibition effect of 6-bromo-3-nitro-2-phenylimidazol[1,2-α] pyridine (BNPP) on the corrosion of C38 steel in 0.5 M H2SO4 was studied by weight loss , electrochemical methods. The results showed that BNPP was a good inhibitor in 0.5 M H2SO4 and this adsorption obeyed the Langmuir adsorption isotherm. The results obtained from the different corrosion evaluation techniques are in good agreement. Polarization curves showed that BNPP acted as a mixed-type inhibitor in sulfuric acid. The effect of the temperature on the corrosion behavior with addition of 10-3M of the inhibitor was studied in the temperature range 298-328 K, and the thermodynamic parameters were determined and discussed. Quantum chemical approach, using the density functional theory (DFT), was applied in order to get better understanding about the relationship between the inhibition efficiency and molecular structure of BNPP. The theoretical results were found to be consistent with the experimental data

Assessment of Drug Related Problems and Pharmacist Interventions in Inpatients with Cardiovascular Disease

Aim. To identify and evaluate the nature and incidence of drug-related problems (DRPs) and to manifest the role of a pharmacist in ensuring safe and efficient use of medications with cardiovascular disease patients by using PCNE Classification to assess and report drug-related problems.Material and Methods. An Observational and Prospective study was conducted in a tertiary care hospital of medicine department of general and intensive/critical care units for a period of 6 months to identify and evaluate the nature and incidence of DRP’s and to manifest the role of a pharmacist in ensuring safe and efficient use of medications with cardiovascular disease patients by using PCNE Classification to assess and report drug-related problems.Results. Of 94 Patient profiles were evaluated out of which 78 (82.9%) patient profiles were identified with 208 DRPs. Among 208, 140 (67.3%) drug interactions, 15 (7.2%) untreated indication, 12 (5.8%) adverse drug reactions, 10 (4.8%) drug use without indication, 8 (3.8%) drug underused, 8 (3.8%) duration of treatment too short, 5 (2.4%) dose unclear, 4 (1.9%) inappropriate drug form, 3 (1.4%) duration of treatment too long, 2 (1.0%) too many drugs prescribed for an indication, 1 (0.5%) drug overused. For 208 DRPs identified and provided with 74 interventions which includes 30 (41.6%) drug discontinuation, 24 (33.3%) addition of a new drug, 4 (5.55%) change of dosage form, and 14 (19.4%) decrease the dose.Conclusion. The present study revealed that patients with cardiovascular diseases suffer from numerous DRPs that can be identified, resolved, or prevented to some extent by pharmacist intervention. Hence the study addresses the importance of clinical pharmacist in the management of DRPs among cardiovascular patients

Lemongrass essential oil gel as a local drug delivery agent for the treatment of periodontitis

Background: It has been long recognized that periodontal diseases are infections of the periodontium, comprising the bacterial etiology, an immune response, and tissue destruction. Treatment strategies aiming primarily at suppressing or eliminating specific periodontal pathogens include adjunct use of local and systemic antibiotics as part of nonsurgical periodontal therapy. Unwanted side effects and resistance of microorganisms toward antibiotics due to their widespread use have modified the general perception about their efficacy. Research in phytosciences has revealed various medicinal plants offering a new choice of optional antimicrobial therapy. Cymbopogon citratus, Stapf. (lemongrass) is a popular medicinal plant. At a concentration ≤2%, lemongrass essential oil inhibits the growth of several kinds of microorganisms including periodontal pathogens, especially the reference strains Actinomyces naeslundii and Porphyromonas gingivalis, which were resistant to tetracycline hydrochloride. Aims: To evaluate the efficacy of locally delivered 2% lemongrass essential oil in gel form as an adjunct to scaling and root planing, as compared to scaling and root planing alone for the treatment of chronic periodontitis. Materials and Methods: 2% Lemongrass essential oil gel was prepared and placed in moderate to deep periodontal pockets after scaling and root planing. Results: Statistically significant reduction in probing depth and gingival index and gain in relative attachment level were noted in the experimental group as compared to the control group at 1 and 3 months. Conclusion: Locally delivered 2% lemongrass essential oil gel offers a new choice of safe and effective adjunct to scaling and root planing in periodontal therapy

Prevalence of Post-operative Wound Infections in Rural area of Latur District

Background: Surgical site infection (SSI) continues to be a major source of morbidity following operative procedures. The modern surgeon cannot escape the responsibility of dealing with infections, having the knowledge for the appropriate use of aseptic and antiseptic technique, proper use of prophylactic and therapeutic antibiotics, and adequate monitoring and support with novel surgical and pharmacologic as well as nonpharmacologic aids. Objective: To study the most common organisms encountered in postoperative wound infections and to find out the most effective Antibiotics in case of Post Operative Wound Infections. Methodology: It is an Observational study done on 50 operated cases of post operative wounds. Results: Most common microorganism encountered in present series was E. coli in 13 cases (26%). Least common micro organism was Proteus (2%). E. coli was also encountered in mixed culture with Kleibsiella, Pseudomonas and Citrobacter. Most effective antibiotic in present series was Imipenem. Other common effective antibiotics were Amikacin, Netillin, Piperacillin, Tetracycline and Gentamycin. Least effective antibiotics were Penicillin, Cefotaxime, Cefuroxime and Cefoxitin. Conclusion: E. coli was the most common organism cultured. Imipenem and Amikacin were the most effective antibiotics

An Interesting Case of Perforated Meckel’s Diverticulum

Meckel’s diverticulum is one of the common congenital anomalies of the small intestine that occurs in approximately 2% of population, with equal incidence in both sexes. It is caused by an incomplete obliteration of omphalomesenteric duct. It is a true diverticulum, containing all the three layers; complications are known in 4% of cases in adults. Here, we present an interesting case of a gangrenous Meckel’s diverticulum simulating appendicular lump, which was treated with Oschner Sherren’s regime

A REVIEW OF STUDIES ON PHYTOREMEDIATION TECHNOLOGY TO UPGRADE DOMESTIC

The fast growing development in the waste water use leads to the drastic change in the environment which is the main challenge to scientist & the natural income. The Domestic waste water show an adverse effect on the water excellence parameter like as D.O., B.O.D., C.O.D., pH, Conductivity & temperature of the nearby aqua system. The irregular level of these parameters reason pollution in water bodies & even death of aqua life. though domestic waste water is found dangerous and it can come in in environment through various waste water channels, Phytoremediation system has been create possible to improve sewage quality to bulky amount without any secondary smog. The current explore focus on the different investigations perform on evidence of potential of selected aquatic fix like Aloe vera, Canna Indica, Taro etc. These plants are used for reducing above parameter in domestic waste water. The changes in the waste water quality parameters through the conduct of Phytoremediation which plants be proving occasionally to improving the waste water treatment process

Crystal structure of 1 `-ethylspirochroman-4,4 `-imidazolidine]-2 `,5 `-dione: a hydantoine derivative

The title compound, C13H13N2O3, a hydantoin derivative, crystallized with two molecules (A and B) in an asymmetric unit. In molecule A, the imidazolidine ring is twisted about the C -N bond involving the spiro C atom, while in molecule B this ring is flat (r.m.s. deviation = 0.010 angstrom). The pyran rings in both molecules have distorted half-chair conformations. The mean plane of the imidazolidine ring is inclined to the aromatic ring of the chroman unit by 79.71 (11) in molecule A and 82.83 (12) in molecule B. In the crystal, pairs of N-H center dot center dot center dot O hydrogen bonds link the individual molecules to form A-A and B-B inversion dimers. The dimers are linked via N-H center dot center dot center dot O and C-H center dot center dot center dot O hydrogen bonds, forming sheets lying parallel to the be plane, viz. (011). Within the sheets, the A and B molecules are linked by C-H center dot center dot center dot pi interactions

A Review of Studies on Phytoremediation Technology to Upgrade Domestic

The Fast growing development in the waste water use leads to the drastic change in the environment which is the main challenge to scientist & the natural income. The Domestic waste water show an adverse effect on the water excellence parameter like as D.O., B.O.D., C.O.D., pH, Conductivity & temperature of the nearby aqua system. The irregular level of these parameters reason pollution in water bodies & even death of aqua life. though domestic waste water is found dangerous and it can come in in environment through various waste water channels, Phytoremediation system has been create possible to improve sewage quality to bulky amount without any secondary smog. The current explore focus on the different investigations perform on evidence of potential of selected aquatic fix like Aloe vera, Canna Indica, Taro etc. These plants are used for reducing above parameter in domestic waste water. The changes in the waste water quality parameters through the conduct of Phytoremediation which plants be proving occasionally to improving the waste water treatment process

Methyl 2-(benzo­yl­oxy)benzoate

In the title compound, C\sb 15H\sb 12O\sb 4, the arene rings are inclined at an angle of 65.97(6)\circ. The pendant methyl ester substituent has an extended conformation. In the crystal, mol\-ecules are linked by C—-H⋅sπ inter\-actions, forming chains propagating along the \it b-axis direction. The chains are linked \it via offset π—π inter\-actions inter{\-}centroid distance = 3.640(1){\AA}, forming sheets parallel to (10-1)