10,017 research outputs found
Top quark physics at muon and other future colliders
The top quark will be extensively studied at future muon colliders. The
threshold cross section can be measured precisely, and the small beam energy
spread is especially effective at making the measurement useful. We report on
all the activities of the top quark working group, including talks on top quark
physics at other future colliders.Comment: 16 pages, 9 figures, Summary report of the Top Quark Working Group at
the Workshop on Physics at the First Muon Collider and at the Front End of a
Muon Collider, November 6-9, 1997, Fermi National Accelerator Laborator
The impact of chorionicity on pregnancy outcome and neurodevelopment at 2 years old among twins born preterm: the EPIPAGE-2 cohort study
OBJECTIVE
To compare the short‐ and mid‐term outcomes of preterm twins by chorionicity of pregnancy.
DESIGN
Prospective nationwide population‐based EPIPAGE‐2 cohort study.
SETTING
546 maternity units in France, between March and December 2011.
POPULATION
A total of 1700 twin neonates born between 24 and 34 weeks of gestation.
METHODS
The association of chorionicity with outcomes was analysed using multivariate regression models.
MAIN OUTCOME MEASURES
First, survival at 2‐year corrected age with or without neurosensory impairment, and second, perinatal, short‐, and mid‐term outcomes (survival at discharge, survival at discharge without severe morbidity) were described and compared by chorionicity.
RESULTS
In the EPIPAGE 2 cohort, 1700 preterm births were included (850 twin pregnancies). In all, 1220 (71.8%) were from dichorionic (DC) pregnancies and 480 from monochorionic (MC) pregnancies. MC pregnancies had three times more medical terminations than DC pregnancies (1.67 versus 0.51%, P < 0.001), whereas there were three times more stillbirths in MC than in DC pregnancies (10.09 versus 3.78%, P < 0.001). Both twins were alive at birth in 86.6% of DC pregnancies compared with 80.0% among MC pregnancies (P = 0.008). No significant difference according to chorionicity was found regarding neonatal deaths and morbidities. Likewise, for children born earlier than 32 weeks, the 2‐year follow‐up neurodevelopmental results were not significantly different between DC and MC twins.
CONCLUSIONS
This study confirms that MC pregnancies have a higher risk of adverse outcomes. However, the outcomes among preterm twins admitted to neonatal intensive care units are similar irrespective of chorionicity
Surveillance Mammography in Older Patients With Breast Cancer—Can We Ever Stop?: A Review
Approximately 4–5% of breast cancer survivors will develop a new ipsilateral or contralateral cancer (“in-breast event”) over the 5 years following diagnosis, and annual surveillance mammography is recommended for those with residual breast tissue. The risk for such in-breast events persists over time, though increasing age at cancer diagnosis and treatment with hormonal therapy are associated with lower risk, and most older breast cancer survivors will ultimately die from non-breast cancer related causes. Specific guidelines for surveillance strategies in older patients are limited. Prospective data on the benefits and harms of surveillance mammography in this population are lacking, and most of the evidence is derived from observational, retrospective data, often in the general population
Early Fermi Gamma-ray Space Telescope Observations of the Quasar 3C 454.3
This is the first report of Fermi Gamma-ray Space Telescope observations of
the quasar 3C 454.3, which has been undergoing pronounced long-term outbursts
since 2000. The data from the Large Area Telescope (LAT), covering 2008 July 7
- October 6, indicate strong, highly variable gamma-ray emission with an
average flux of ~3 x 10^{-6} photons cm^{-2} s^{-1}, for energies above 100
MeV. The gamma-ray flux is variable, with strong, distinct,
symmetrically-shaped flares for which the flux increases by a factor of several
on a time scale of about three days. This variability indicates a compact
emission region, and the requirement that the source is optically thin to
pair-production implies relativistic beaming with Doppler factor delta > 8,
consistent with the values inferred from VLBI observations of superluminal
expansion (delta ~ 25). The observed gamma-ray spectrum is not consistent with
a simple power-law, but instead steepens strongly above ~2 GeV, and is well
described by a broken power-law with photon indices of ~2.3 and ~3.5 below and
above the break, respectively. This is the first direct observation of a break
in the spectrum of a high luminosity blazar above 100 MeV, and it is likely
direct evidence for an intrinsic break in the energy distribution of the
radiating particles. Alternatively, the spectral softening above 2 GeV could be
due to gamma-ray absorption via photon-photon pair production on the soft X-ray
photon field of the host AGN, but such an interpretation would require the
dissipation region to be located very close (less than 100 gravitational radii)
to the black hole, which would be inconsistent with the X-ray spectrum of the
source.Comment: Accepted by the Astrophysical Journal; corresponding authors: Greg
Madejski ([email protected]) and Benoit Lott ([email protected]
Fermi Large Area Telescope Measurements of the Diffuse Gamma-Ray Emission at Intermediate Galactic Latitudes
The diffuse Galactic gamma-ray emission is produced by cosmic rays (CRs)
interacting with the interstellar gas and radiation field. Measurements by the
Energetic Gamma-Ray Experiment Telescope (EGRET) instrument on the Compton
Gamma-Ray Observatory indicated excess gamma-ray emission > 1 GeV relative to
diffuse Galactic gamma-ray emission models consistent with directly measured CR
spectra (the so-called ``EGRET GeV excess''). The excess emission was observed
in all directions on the sky, and a variety of explanations have been proposed,
including beyond-the-Standard-Model scenarios like annihilating or decaying
dark matter. The Large Area Telescope (LAT) instrument on the Fermi Gamma-ray
Space Telescope has measured the diffuse gamma-ray emission with improved
sensitivity and resolution compared to EGRET. We report on LAT measurements of
the diffuse gamma-ray emission for energies 100 MeV to 10 GeV and Galactic
latitudes 10 deg. <= |b| <= 20 deg. The LAT spectrum for this region of the sky
is well reproduced by a diffuse Galactic gamma-ray emission model that is
consistent with local CR spectra and inconsistent with the EGRET GeV excess.Comment: 2 figures, 1 table, accepted by Physical Review Letters, available
online Dec. 18th, 200
Fermi Large Area Telescope Observations of the Cosmic-Ray Induced gamma-ray Emission of the Earth's Atmosphere
We report on measurements of the cosmic-ray induced gamma-ray emission of
Earth's atmosphere by the Large Area Telescope onboard the Fermi Gamma-ray
Space Telescope. The LAT has observed the Earth during its commissioning phase
and with a dedicated Earth-limb following observation in September 2008. These
measurements yielded 6.4 x 10^6 photons with energies >100MeV and ~250hours
total livetime for the highest quality data selection. This allows the study of
the spatial and spectral distributions of these photons with unprecedented
detail. The spectrum of the emission - often referred to as Earth albedo
gamma-ray emission - has a power-law shape up to 500 GeV with spectral index
Gamma = 2.79+-0.06.Comment: Accepted for publication in PR
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