Lithospheric structure in the Pacific geoid

The high degree and order SEASAT geoid in the central Pacific correlates closely with the structure of the cooling lithosphere. Relative changes in plate age across major fracture zones in relatively young seafloor frame the east-west trending pattern formed by the geoid anomalies. The field removal in bathymetry corresponds to removal of some of the low degree and order geoidal components, the step like structure across fracture zones is also removed. The regional thermal subsidence was removed from the bathymetry by subtracting a mean subsidence surface from the observed bathymetry. This produces a residual bathymetry map analogous to the usual residual depth anomaly maps. The residual bathymetry obtained in this way contains shallow depths for young seafloor, and larger depths for older seafloor, thus retaining the structure of the lithosphere while removing the subsidence of the lithosphere

Reasonableness, Murder, and Modern Science

Originally titled “Is It Murder in Tennessee to Kill a Chimpanzee,” this article argues in some detail that typical legal definitions of “murder” as involving the intentional killing of “a reasonable being” would require classifying the intentional killing of chimpanzees as murder

Geologic applications of thermal inertia image using HCMM data

The author has identified the following significant results. Comparison of a simulated HCMM image of the Pisgah Crater, California test site obtained from aircraft data with an image generated from the preliminary satellite data tape of the area indicates that the HCMM satellite data appears much as predicted by the simulation

The Future is Now: the Formation of Single Low Mass White Dwarfs in the Solar Neighborhood

Low mass helium-core white dwarfs (M < 0.45 Msun) can be produced from interacting binary systems, and traditionally all of them have been attributed to this channel. However, a low mass white dwarf could also result from a single star that experiences severe mass loss on the first ascent giant branch. A large population of low mass He-core white dwarfs has been discovered in the old metal-rich cluster NGC 6791. There is therefore a mechanism in clusters to produce low mass white dwarfs without requiring binary star interactions, and we search for evidence of a similar population in field white dwarfs. We argue that there is a significant field population (of order half of the detected systems) that arises from old metal rich stars which truncate their evolution prior to the helium flash from severe mass loss. There is a consistent absence of evidence for nearby companions in a large fraction of low mass white dwarfs. The number of old metal-rich field dwarfs is also comparable with the apparently single low mass white dwarf population, and our revised estimate for the space density of low mass white dwarfs produced from binary interactions is also compatible with theoretical expectations. This indicates that this channel of stellar evolution, hitherto thought hypothetical only, has been in operation in our own Galaxy for many billions of years. One strong implication of our model is that single low mass white dwarfs should be good targets for planet searches because they are likely to arise from metal-rich progenitors. We also discuss other observational tests and implications, including the potential impact on SN Ia rates and the frequency of planetary nebulae.Comment: ApJ published versio

Problematic advice from suicide prevention experts

Based on a 10-year systematic review of suicide prevention strategies, 29 suicide prevention experts from 17 European countries recommend four allegedly evidence-based strategies to be included in national suicide prevention programs. One of the recommended strategies is pharmacological treatment of depression. This recommendation is deeply problematic for several reasons. First, it is based on a biased selection and interpretation of available evidence. Second, the authors have failed to take into consideration the widespread corruption in the research on antidepressants. Third, the many and serious side effects of antidepressants are not considered. Thus, the recommendation may have deleterious consequences for countless numbers of people, and, in fact, contribute to an increase in the suicide rate rather than a decrease

Acute lung injury in paediatric intensive care: course and outcome

Introduction: Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) carry a high morbidity and mortality (10-90%). ALI is characterised by non-cardiogenic pulmonary oedema and refractory hypoxaemia of multifactorial aetiology [1]. There is limited data about outcome particularly in children. Methods This retrospective cohort study of 85 randomly selected patients with respiratory failure recruited from a prospectively collected database represents 7.1% of 1187 admissions. They include those treated with High Frequency Oscillation Ventilation (HFOV). The patients were admitted between 1 November 1998 and 31 October 2000. Results: Of the 85, 49 developed acute lung injury and 47 had ARDS. There were 26 males and 23 females with a median age and weight of 7.7 months (range 1 day-12.8 years) and 8 kg (range 0.8-40 kg). There were 7 deaths giving a crude mortality of 14.3%, all of which fulfilled the Consensus I [1] criteria for ARDS. Pulmonary occlusion pressures were not routinely measured. The A-a gradient and PaO2/FiO2 ratio (median + [95% CI]) were 37.46 [31.82-43.1] kPa and 19.12 [15.26-22.98] kPa respectively. The non-survivors had a significantly lower PaO2/FiO2 ratio (13 [6.07-19.93] kPa) compared to survivors (23.85 [19.57-28.13] kPa) (P = 0.03) and had a higher A-a gradient (51.05 [35.68-66.42] kPa) compared to survivors (36.07 [30.2-41.94]) kPa though not significant (P = 0.06). Twenty-nine patients (59.2%) were oscillated (Sensormedics 3100A) including all 7 non-survivors. There was no difference in ventilation requirements for CMV prior to oscillation. Seventeen of the 49 (34.7%) were treated with Nitric Oxide including 5 out of 7 non-survivors (71.4%). The median (95% CI) number of failed organs was 3 (1.96-4.04) for non-survivors compared to 1 (0.62-1.62) for survivors (P = 0.03). There were 27 patients with isolated respiratory failure all of whom survived. Six (85.7%) of the non-survivors also required cardiovascular support.Conclusion: A crude mortality of 14.3% compares favourably to published data. The A-a gradient and PaO2/FiO2 ratio may be of help in morbidity scoring in paediatric ARDS. Use of Nitric Oxide and HFOV is associated with increased mortality, which probably relates to the severity of disease. Multiple organ failure particularly respiratory and cardiac disease is associated with increased mortality. ARDS with isolated respiratory failure carries a good prognosis in children

A Critical Review of Deep Learning-Based Multi-Sensor Fusion Techniques

In this review, we provide a detailed coverage of multi-sensor fusion techniques that use RGB stereo images and a sparse LiDAR-projected depth map as input data to output a dense depth map prediction. We cover state-of-the-art fusion techniques which, in recent years, have been deep learning-based methods that are end-to-end trainable. We then conduct a comparative evaluation of the state-of-the-art techniques and provide a detailed analysis of their strengths and limitations as well as the applications they are best suited for

Point-of-care measurement of blood lactate in children admitted with febrile illness to an African District Hospital.

BACKGROUND: Lactic acidosis is a consistent predictor of mortality owing to severe infectious disease, but its detection in low-income settings is limited to the clinical sign of "deep breathing" because of the lack of accessible technology for its measurement. We evaluated the use of a point-of-care (POC) diagnostic device for blood lactate measurement to assess the severity of illness in children admitted to a district hospital in Tanzania. METHODS: Children between the ages of 2 months and 13 years with a history of fever were enrolled in the study during a period of 1 year. A full clinical history and examination were undertaken, and blood was collected for culture, microscopy, complete blood cell count, and POC measurement of blood lactate and glucose. RESULTS: The study included 3248 children, of whom 164 (5.0%) died; 45 (27.4%) of these had raised levels of blood lactate (>5 mmol/L) but no deep breathing. Compared with mortality in children with lactate levels of ≤ 3 mmol/L, the unadjusted odds of dying were 1.6 (95% confidence interval [CI].8-3.0), 3.4 (95% CI, 1.5-7.5), and 8.9 (95% CI, 4.7-16.8) in children with blood lactate levels of 3.1-5.0, 5.1-8.0, or >8.0 mmol/L, respectively. The prevalence of raised lactate levels (>5 mmol/L) was greater in children with malaria than in children with nonmalarial febrile illness (P < .001) although the associated mortality was greater in slide-negative children. CONCLUSIONS: POC lactate measurement can contribute to the assessment of children admitted to hospital with febrile illness and can also create an opportunity for more hospitals in resource-poor settings to participate in clinical trials of interventions to reduce mortality associated with hyperlactatemia

Academic self-concept, gender and single-sex schooling

This paper assesses gender differences in academic self-concept for a cohort of children born in 1958 (the National Child Development Study). We address the question of whether attending single-sex or co-educational schools affected students’ perceptions of their own academic abilities (academic self-concept). Academic selfconcept was found to be highly gendered, even controlling for prior test scores. Boys had higher self-concepts in maths and science, and girls in English. Single-sex schooling reduced the gender gap in self-concept, while selective schooling was linked to lower academic self-concept overall